Xinyu Di
Guest researcher
- Name
- Dr. X. Di
- Telephone
- +31 71 527 2727
- x.di@lic.leidenuniv.nl
Guest researcher
- Science
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Molecular Physiology
- Di X., Martinez-Tellez B., Krekels E.H.J., Jurado-Fasoli L., Osuna-Prieto F.J., Ortiz-Alvarez L., Hankemeier T., Rensen P.C.N., Ruiz J.R. & Kohler I. (2024), Higher plasma levels of endocannabinoids and analogues correlate with a worse cardiometabolic profile in young adults, Journal of Clinical Endocrinology and Metabolism : 1-10 (dgad668).
- Jiang M., Huizenga M.C.W., Wirth J.L., Paloczi J., Amedi A., Berg R.J.B.H.N. van den, Benz J., Collin L., Deng H., Di X., Driver W.F., Florea B.I., Grether U., Janssen A.P.A., Hankemeier T., Heitman L.H., Lam T.W., Mohr F., Pavlovic A., Ruf I., Hurk H. van den, Stevens A.F., Vliet D. van der, Wel T. van der, Wittwer M.B., Boeckel C.A.A. van, Pacher P., Hohmann A.G. & Stelt M. van der (2023), A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence, Nature Communications 14(1): 8039.
- Di X. (7 February 2023), Exploration of the endocannabinoid system using metabolomics (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Hankemeier T., Kohler I. & Krekels E.H.J.
- He B.S., Di X., Gulded F., Harder A.V.E., Maagdenberg A.M.J.M. van den, Terwindt G.M., Krekels E.H.J., Kohler I., Harms A.C., Ramautar R. & Hankemeier T. (2022), Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method, Analytica Chimica Acta 1210: 339888.
- Jurado-Fasoli L., Di X., Sanchez-Delgado G., Yang W., Osuna-Prieto F.J., Ortiz-Alvarez L., Krekels E., Harms A.C., Hankemeier T., Schonke C., Aguilera C.M., Llamas-Elvira J.M., Kohler I., Rensen P.C.N., Ruiz J.R. & Martinez-Tellez B. (2022), Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trial, EBioMedicine 85: 104313.
- Ortiz-Alvarez L., Xu H., Di X., Kohler I., Osuna-Prieto F.J., Acosta F.M., Vilchez-Vargas R., Link A., Plaza-Díaz J., Stelt M. van der, Hankemeier T., Clemente-Postigo M., Tinahones F.J., Gil A., Rensen P.C.N., Ruiz J.R. & Martinez-Tellez B. (2022), Plasma levels of endocannabinoids and their analogues are related to specific fecal bacterial genera in young adults: role in gut barrier integrity, Nutrients 14(10): 2143.
- Jurado-Fasoli L., Di X.Y., Kohler I., Osuna-Prieto F.J., Hankemeier T., Krekels E.H.J., Harms A.C., Yang W., Garcia-Lario J.V., Fernandez-Veledo S., Ruiz J.R., Rensen P.C.N. & Martinez-Tellez B. (2022), Omega-6 and omega-3 oxylipins as potential markers of cardiometabolic risk in young adults, Obesity 30(1): 50-61.
- Osuna-Prieto F.J., Martinez-Tellez B., Ortiz-Alvarez L., Di X.Y., Jurado-Fasoli L., Xu H.W., Ceperuelo-Mallafre V., Nunez-Roa C., Kohler I., Segura-Carretero A., Garcia-Lario J.W., Gil A., Aguilera C.M., Llamas-Elvira J.M., Rensen P.C.N., Vendrell J., Ruiz J.R. & Fernández-Veledo S. (2021), Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults, Cardiovascular Diabetology 20(1): 151.
- Osuna-Prieto F.J., Martinez-Tellez B., Ortiz-Alvarez L., Di X.Y., Jurado-Fasoli L., Xu H.W., Ceperuelo-Mallafre V., Nunez-Roa C., Kohler I., Segura-Carretero A., Garcia-Lario J.W., Gil A., Aguilera C.M., Llamas-Elvira J.M., Rensen P.C.N., Vendrell J., Ruiz J.R. & Fernández-Veledo S. (2021), Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults, Cardiovascular Diabetology 20(1): 151.
- Zhou J., Mock E.D., Al Ayed K., Di X., Kantae V., Burggraaff L., Stevens A.F., Martella A., Mohr F., Jiang M., Wel T. van der, Wendel T.J., Ofman T.P., Tran Y., Koster N. de, Westen G.J.P. van, Hankemeier T. & Stelt M. van der (2020), Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family, Journal of Medicinal Chemistry 63(17): 9340-9359.
- Mock E.D., Mustafa M., Gunduz-Cinar O., Cinar R., Petrie G.N., Kantae V., Di X., Ogasawara D., Varga Z.V., Paloczi J., Miliano C., Donvito G., Esbroeck A.C.M. van, Gracht A.M.F. van der, Kotsogianni I., Park J.K., Martella A., Wel T. van der, Soethoudt M., Jiang M., Wendel T.J., Janssen A.P.A., Bakker A.T., Donovan C.M., Castillo L.I., Florea B.I., Wat J., Hurk H. van den, Wittwer M., Grether U., Holmes A., Boeckel C.A.A. van, Hankemeier T., Cravatt B.F., Buczynski M.W., Hill M.N., Pacher P., Lichtman A.H. & Stelt M. van der (2020), Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nature Chemical Biology 16(6): 667-675.
- Esbroeck A.C.M. van, Varga Z.V., Di X., Rooden E.J. van, Tóth V.E., Onódi Z., Kuśmierczyk M., Leszek P., Ferdinandy P., Hankemeier T., Stelt M. van der & Pacher P. (2019), Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system, Pharmacological Research 151: 104578.
- Esbroeck A.C.M. van, Kantae V., Di X., Wel T. van der, Dulk J. den, Stevens A.F., Singh S., Bakker A.T., Florea B.I., Stella N., Overkleeft H.S., Hankemeier T. & Stelt M. van der (2019), Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells, Frontiers in Molecular Neuroscience 12: 286.
- Esbroeck A.C.M. van, Kantae V., Di X., Wel T. van der, Dulk J. den, Stevens A.F., Singh S., Bakker A.T., Florea B.I., Stella N., Overkleeft H.S., Hankemeier T. & Stelt M. van der (2019), Identification of α,β-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells, Frontiers in Molecular Neuroscience 12: 286.