Steven Kunnen
Postdoc
- Name
- Dr.ir. S.J. Kunnen Ph.D.
- Telephone
- +31 71 527 2727
- s.j.kunnen@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0001-9549-1719
Postdoc
- Faculty of Science
- Leiden Academic Centre for Drug Research
- LACDR/Toxicology
- Wijaya L.S., Kunnen S.J., Trairatphisan P., Fisher C.P., Crosby M.E., Schaefer K., Bodié K., Vaughan E.E., Breidenbach L., Reich T., Clausznitzer D., Bonnet S.A., Zheng S., Pont C.M., Stevens J.L., Le Dévédec S.E. & Water B. van de (2025), Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage, and regeneration response after cisplatin, Cell Biology and Toxicology 41(1): 49.
- Meijer T., Braak S.J. ter, Wolters L., Kunnen S.J., Islam B., Suciu I., Gardner I., Hatley O., Currie R., Hardy B., Leist M., Water B. van de, Jennings P. & Wilmes A. (2025), Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models, Toxicology In Vitro 104: 106010.
- Kunnen S.J., Callegaro G., Sutherland J.J., Trairatphisan P., Kessel H.W. van, Wijaya L.S., Chung G., Pye K., Goldstein K.M., Teague C.R., Fisher C.P., Saez-Rodriguez J., Brown C., Elmore S.A., Heinz-Taheny K.M., Stevens J.L. & Water B. van de (2025), Utilizing rat kidney gene co-expression networks to enhance safety assessment biomarker identification and human translation, iScience 28(7): 112978.
- Kunnen S.J., Arnesdotter E., Willenbockel C.T., Vinken M. & Water B. van de (2024), Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment, ALTEX - Alternatives to Animal Experimentation 41(2): 213-232.
- Callegaro G., Schimming J.P., Piñero González J., Kunnen S.J., Wijaya L.S., Trairatphisan P., Berk L. van den, Beetsma K., Furlong L.I., Sutherland J.J., Mollon J., Stevens J.L. & Water B. van de (2023), Identifying multiscale translational safety biomarkers using a network-based systems approach, iScience 26(3): 106094.
- Vrijenhoek N.G., Wehr M.M., Kunnen S.J., Wijaya L.S., Callegaro G., Moné M.J., Escher S.E. & Water B. van de (2022), Application of high-throughput transcriptomics for mechanism-based biological read-across of short-chain carboxylic acid analogues of valproic acid, ALTEX - Alternatives to Animal Experimentation : .
- Callegaro G., Kunnen S.J., Trairatphisan P., Grosdidier S., Niemeijer M., Hollander W. den, Guney E., Piñero Gonzalez J., Furlong L., Webster Y.W., Saez-Rodriguez J., Sutherland J.J., Mollon J., Stevens J.L. & Water B. van de (2021), The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment, Archives of Toxicology 95(12): 3745-3775.
- Kunnen S.J. (27 September 2018), Shear stress regulated signaling in renal epithelial cells and polycystic kidney disease (Dissertatie, Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University). Supervisor(s): Peters D.J.M.