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Dr. Niki Antypa was born on the island of Chios, Greece. During the years 2000-2004 she studied Psychology at the American College of Greece where she obtained the degree Bachelor of Arts in Psychology with High Distinction. She then moved to the Netherlands to study clinical psychology and at the end of 2006 she obtained her MSc in Psychology (cum laude) from Leiden University. From 2007 till 2011 she worked at the department of Clinical Psychology as a PhD student and in June 2011 she obtained her PhD degree. Her dissertation focused on cognitive vulnerability to depression, including the influence of genetic, environmental and nutritional factors.
With a Rubicon grant awarded by N.W.O. (Dutch Scientific Organization) she carried out post-doctoral research at the Institute of Psychiatry, at the University of Bologna, in Italy. Since May 2014, she works as an Assistant Professor at the department of Clinical Psychology.
Her research focuses on the area of chronobiology of depression and suicide. She is particularly interested in the role of the circadian clock (a person’s chronotype) in interaction with other psychological and environmental influences that determine people’s vulnerability to depression and suicide (chronobiology of depression). Currently she is testing a pilot intervention program that aims to improve sleep and mood problems in a student population: the SMILE study.
Thesis supervision (bachelor and master); Clinical Internship supervision; Internal Practice Internship instructor and supervisor
Lecturer for Biological Underpinnings of Psychopathology, Frontiers of Science course (guest Lecturer LUMC)
Rubicon grant awarded by N.W.O. (Dutch Scientific Organization) – Principal Investigator - 2 years (2011-2013) post-doctoral research at the Institute of Psychiatry, at the University of Bologna, in Italy. Title: “Genetic and environmental pathways to personalized treatment in depression”
Onderzoekstalent Grant / Research Talent grant awarded by N.W.O. (Dutch Scientific Organization) – Principal Investigator – Leiden University (2019- 2023) “Title: 'Rise and fall: Daily fluctuations in suicidal ideation'” (link to the SAFE study)
Member of the Educational committee of the Dutch Association of Sleep-Wake Research (Nederlandse vereniging voor Slaap – Waak Onderzoek) https://www.nswo.nl/ .
- Kivelä L., Krause-Utz A., Mouthaan J., Schoorl M., Kleine R. de, Elzinga B., Eikelenboom M., Penninx B.W.J.H., Does W. van der & Antypa N. (2019), Longitudinal course of suicidal ideation and predictors of its persistence – A NESDA study, Journal of Affective Disorders 257: 365-375.
- Druiven S.J.M., Knapen S.E., Penninx B.W.J.H., Antypa N., Schoevers R.A. , Riese H. & Meesters Y. (2019), Can chronotype function as predictor of a persistent course of depressive and anxiety disorder?, Journal of Affective Disorders 242: 159-164.
- Van den Berg J.F., Kivelä L. & Antypa N. (2018), Chronotype and depressive symptoms in students: An investigation of possible mechanisms, Chronobiology International 35(9): 1248-1261.
- Kivelä L., Papadopoulos M. & Antypa N. (2018), Chronotype and Psychiatric Disorders, Current Sleep Medicine Reports 4(2): 94-103.
- Kerpershoek M.L., Antypa N. & Van den Berg J.F. (2018), Evening use of caffeine moderates the relationship between caffeine consumption and subjective sleep quality in students, Journal of Sleep Research 27(5): e12670.
- Knapen S.E., Riemersma-van der Lek R.F., Antypa N., Meesters Y., Penninx .B.W.J.H. & Schoevers R.A. (2018), Social jetlag and depression status: Results obtained from the Netherlands Study of Depression and Anxiety., Chronobiology International 35(1): 1-7.
- Antypa N., Verkuil B., Molendijk M.L., Schoevers R., Penninx B.W.J.H. & Van Der Does A.J.W. (2017), Associations between chronotypes and psychological vulnerability factors of depression, Chronobiology International 34(8): 1125-1135.
- Tollenaar M.S., Molendijk M.L., Penninx B.W., Milaneschi Y. & Antypa N. (2017), The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene, European Archives of Psychiatry and Clinical Neuroscience 267(6): 517–526.
- Balestri M., Crisafulli C., Donato L., Giegling I., Calati R, Antypa N., Schneider B., Marusic D., Tarozzi M.E., Marusic D, Paragi M., Hartmann A.M., Konte B., Marsano A., Serretti A. & Rujescu D.. (2017), Nine differentially expressed genes from a post mortem study and their association with suicidal status in a sample of suicide completers, attempters and controls, Journal of Psychiatric Research 91: 98-104.
- Solis E., Antypa N., Conijn J.M., Kelderman H. & Does A.J.W. van der (2017), Psychometric Properties of the Leiden Index of Depression Sensitivity (LEIDS), Psychological Assessment 29(2): 158-171.
- Antypa N., Souery D., Tomasini M., Albani D., Fusco F., Mendlewicz J. & Serretti A. (2016), Clinical and genetic factors associated with suicide in mood disorder patients, European Archives of Psychiatry and Clinical Neuroscience 266(2): 181–193.
- Drago A., Winding T.N. & Antypa N. (2016), Videoconferencing in psychiatry, a meta-analysis of assessment and treatment, European Psychiatry: the journal of the association of European Psychiatrists 36: 29-37.
- Antypa N., Vogelzangs N., Meesters Y., Schoevers R. & Penninx B.W. (2016), Chronotype associations with depression and anxiety disorders in a large cohort study., Depression and Anxiety 33(1): 75-83.
- Antypa N., Calati R. & Serretti A. (2014), The neuropsychological hypothesis of antidepressant drug action revisited. CNS Neurol Disord Drug Targets, CNS & Neurological Disorders - Drug Targets 13(10): 1722-1739.
- Antypa N., Drago A. & Serretti A. (2013), The role of COMT gene variants in depression: Bridging neuropsychological, behavioral and clinical phenotypes, NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 37(8): 1597-1610.
- Antypa N., Smelt A.H.M., Strengholt A. & Does A.J.W. van der (2012), Effects of omega-3 fatty acid supplementation on mood and emotional information processing in recovered depressed individuals, Journal of Psychopharmacology 26(5): 738-743.
- Drost J., Does A.J.W. van der, Antypa N., Zitman F.G., Dyck R. van & Spinhoven P. (2012), General, Specific and Unique Cognitive Factors Involved in Anxiety and Depressive Disorders, Cognitive Therapy and Research 36(6): 621-633.
- Antypa N., Mandelli L., Nearchou F.A., Vaiopoulos C., Stefanis C.N., Serretti A. & Stefanis N.C. (2012), The 3111T/C polymorphism interacts with stressful life events to influence patterns of sleep in females, Chronobiology International 29(7): 891-897.
- Verhoeven F.E.A., Booij L., Kruijt A.-W., Cerit H., Antypa N. & Does A.J.W. van der (2012), The effects of MAOA genotype, childhood trauma, and sex on trait and state-dependent aggression, Brain and Behavior 2(6): 806-813.
- Mandelli F., Antypa N., Nearchou F.A., Valopoulos C., Stefanis C.N., Serretti A. & Stefanis N.C. (2012), The role of serotonergic genes and environmental stress on the development of depressive symptoms and neuroticism, Journal of Affective Disorders 142(1-3): 82-89.
- Antypa N. (21 June 2011), Cognitive vulnerability to depression : genetic and environmental influences (PhD thesis. Psychology, Faculty of Social and Behavioural Sciences, Leiden University). Supervisor(s): Does A.J.W. van der.
- Klok M.D., Giltay E.J., Does A.J.W. van der, Geleijnse J.M., Antypa N., Penninx B.W.J.H., Geus E.J.C. de, Willemsen F., Boomsma D.I., Leeuwen N. van, Zitman F.G., Kloet E.R. de & Rijk R.H. de (2011), A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females, Translational Psychiatry 1: e62.
- Antypa N., Cerit H., Kruijt A.-W., Verhoeven F.E.A. & Van der Does A.J.W. (2011), Relationships among 5-HTT genotype, life events and gender in the recognition of facial emotions, Neuroscience 172(1): 303-313.
- Antypa N., Does A.J.W. van der & Penninx B.W. (2010), Cognitive reactivity: Investigation of a potentially treatable marker of suicide risk in depression., Journal of Affective Disorders 122: 46-52.
- Putman P., Antypa N., Crysovergi P. & Does A.J.W. van der (2010), Exogenous cortisol acutely influences motivated decision making in healthy young men, 208: 257-263.
- Antypa N. & Does A.J.W. van der (2010), Serotonin transporter gene, childhood emotional abuse and cognitive vulnerability to depression, Genes Brain and Behavior 9: 615-620.
- Antypa N., Does A.J.W. van der, Smelt A.H.M. & Rogers R.D. (2009), Omega-3 fatty acids (fish-oil) and depression-related cognition in healthy volunteers, Journal of Psychopharmacology 23: 831-840.