Luthfi Nurhidayat
PhD candidate / guest
- Name
- L. Nurhidayat MSc
- Telephone
- +31 71 527 4021
- l.nurhidayat@biology.leidenuniv.nl
- ORCID iD
- 0000-0002-0625-2984
I am a Ph.D. student working on gecko’s tail regeneration. My research is focused on investigating the genes involved in tail regeneration of the adult tokay gecko (G. gecko), and compare them with those expressed in normal embryonic tail development.
More information about Luthfi Nurhidayat
Supervisor(s)
Research
Regeneration is the ability of an organism to grow a new tissue or organ that can act as a functional replacement for lost or damaged tissue. Invertebrates, such as Hydra sp. and Planarians, show a remarkable regenerative capacity, not only at the tissue level but also at the whole-body level. Regeneration in the vertebrates is more limited, but some taxa (zebra fish, salamander, frogs, and lizards) show impressive regeneration capacity. Lizards (Scincidae, Gekkonidae, Lacertidae) are a common animal model in regeneration studies, and are able to fully regrow their tail after accidental amputation or self-amputation (autotomy). Tail regeneration in lizards includes blastema formation, tail growth and differentiation, and tail maturation resulting a new regenerated tail which shows small differences from the original tail. Regeneration has some similarities with embryonic development, but these similarities are not well understood. In my research, I would like to make a comprehensive characterization of the cellular and molecular mechanisms underlying tail development and regeneration. I am sure that my research, together with other research on lizard tail regeneration, have potential applications in regenerative medicine in the future.
PhD candidate / guest
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
- Alamsyah F., Firdausi N., Nugraheni S.E.D., Fadhlurrahman A.G., Nurhidayat L., Pratiwi R. & Taruno W.P. (2023), Effects of non-contact electric fields on kidney and liver histology in tumour-induced rats, F1000Research 12: 117.
- Retnoaji B., Nurhidayat L., Pratama S.F., Anshori K., Hananya A., Sofyantoro F. & Bessho Y. (2023), Embryonic development of Indonesian native fish yellow rasbora (Rasbora lateristriata), Journal of King Saud University - Science 35(7): 102810.
- Wang M., Rücklin M., Poelmann R.E., Mooij C.L. de, Fokkema M., Lamers G.E.M., Bakker M.A.G. de, Chin E., Bakos L.J., Marone F., Wisse B.J., Ruiter M.C. de, Cheng S., Nurhidayat L., Vijver M.G. & Richardson M.K. (2023), Nanoplastics causes extensive congenital malformations during embryonic development by passively targeting neural crest cells, Environment International 173: 107865.
- Nurhidayat L., Fajar I., Yati A., Prinanda H.H., Irfan M., Afina D., Fadlurrahman A.G., Antara N.Y., Alamsyah F., Taruno W.P. & Pratiwi R. (2022), Evaluation of static electric field exposure on histopathological structure and function of kidney and liver in DMBA- Induced RAT (Rattus norvegicus Berkenhout, 1769), Malaysian Journal of Fundamental and Applied Sciences 18(6): 703-713.
- Alamsyah F., Pratiwi R., Firdausi N., Pello J.I.M., Nugraheni S.E.D., Fadhlurrahman A.G. Nurhidayat L. & Taruno W.P. (2021), Cytotoxic T cells response with decreased CD4/CD8 ratio during mammary tumors inhibition in rats induced by non-contact electric fields, F1000Research 10: 35.
- Nuriliani A., Lukmawati D., Aemeliya V.F. & Nurhidayat L. (2020), Histopathological effects of ethanolic extract of Gaharu’s (Aquilaria malaccensis Lamk.) leaves on liver and kidney of mice (Mus musculus L.) infected by Plasmodium berghei. Trisakti Saragih H., Ilmi M., Nopitasari S., Audinah L., Widyasari A., Arum Sari M., Masri M., Palilu P.T., Prabowo B.H., Soleha S., Solikhah A. & Fitriana N. (Eds.), AIP Conference Proceedings . THE 6TH INTERNATIONAL CONFERENCE ON BIOLOGICAL SCIENCE ICBS 2019: “Biodiversity as a Cornerstone for Embracing Future Humanity” 10 October 2019 - 11 October 2019 no. 2260: AIP Publishing. 040008 .
- Nurhidayat L., Kurniawan Pratama D., Devi N.A. & Rohmah Z. (2020), The development of integument and muscle in regenerated tail of Tokay gecko (Gekko gecko Linnaeus, 1758). Trisakti Saragih H., Ilmi M., Nopitasari S., Audinah L., Widyasari A., Arum Sari M., Masri M., Toban Palilu P., Prabowo B.P., Soleha S., Solikhah A. & Fitriana N. (Eds.), AIP Conference Proceedings . THE 6TH INTERNATIONAL CONFERENCE ON BIOLOGICAL SCIENCE ICBS 2019: “Biodiversity as a Cornerstone for Embracing Future Humanity” 10 October 2019 - 11 October 2019 no. 2260: AIP Publishing. 030009.
- Pratiwi R., Nyoman Y.A., Fadliansyah L.G., Ardiansyah S.A., Nurhidayat L., Sholikhah E.N., Sunarti S., Widyarini S., Fadhlurrahman A.G., Fatmasari H., Tunjung W.A.S., Haryana S.M., Alamsyah F. & Taruno W.P. (2020), CCL2 and IL18 expressions may associate with the anti-proliferative effect of noncontact electro capacitive cancer therapy in vivo [version 2; peer review: 2 approved, 1 approved with reservations], F1000Research 8: 1770.
- Nurhidayat L., Devi N.A. & Fadhillah D. (2020), Histological structure of nerve fiber and blood vessels in regenerated tail of Tokay gecko (Gekko gecko (Linnaeus, 1758). Saragih H.T., Ilmi M., Nopitasari S., Audinah L., Widyasari A., Sari M.A., Masri M., Palilu P.T., Prabowo B.H., Soleha A., Solikhah A. & Fitriana N. (Eds.), AIP Conference Proceedings. THE 6TH INTERNATIONAL CONFERENCE ON BIOLOGICAL SCIENCE ICBS 2019: “Biodiversity as a Cornerstone for Embracing Future Humanity” 10 October 2019 - 11 October 2019 no. 2260: AIP Publishing. 030010.
- Setiawan P.G.M., Tunjung W.A.S & Nurhidayat L. (2016), Effect of diazepam on kidney function and histological structure of white rat's kidney, Berkala Penelitian Hayati = Journal of Biological Researches 22(1): 1-6.
- Retnoaji B., Wulandari R., Nurhidayat L. & Daryono B. (2016), Osteogenesis study of hybrids of Indonesia’s native chicken pelung (Gallus gallus domesticus) with broiler (Gallus gallus domesticus), Asian Journal of Animal and Veterinary Advances 11(8): 498-504.
- Nurhidayat L., Soesilo N. & Sarto M. (2016), Diving strategy of Amyda cartilaginea (Boddaert, 1770) and Cuora amboinensis (Daudin, 1802) in the perspective of respiratory structure and function, AIP Conference Proceedings 1744(1): 020036.