Hanneke Leegwater
- Name
- H. Leegwater MSc
- ORCID iD
- 0000-0001-6003-1544
Hanneke Leegwater is a PhD candidate and junior lecturer at the Division of Drug Discovery and Safety. Her PhD focuses on breast cancer metabolism, using a variety of mechanistic and statistical modeling approaches. She is co-coordinator of the bachelor course Functional Genomics.
- Leegwater H. (19 May 2026), Data-driven approaches to study breast cancer metabolism [Data-gedreven aanpak voor onderzoek naar borstkankermetabolisme] (Dissertatie. LACDR, Faculteit der Wiskunde en Natuurwetenschappen, Leiden University): Ridderprint. Supervisor(s) and Co-supervisor(s): Danen E.H.J. & Water B. van de, Le Dévédec S.E.
- Huang X., Di X., Zuiderwijk M.C., Zhang L., Leegwater H., Davidse S., Kindt A., Harms A.C., Hankemeier T., Le Dévédec S.E. & Ali A. (2025), Lipidomic profiling of triple-negative breast cancer cells reveals distinct metabolic signatures associated with EpCAM expression, Talanta 283: 127127.
- Leegwater H., Zhang Z., Zhang X., Hankemeier T., Harms A.C., Zweemer A.J.M., Le Dévédec S.E. & Kindt A.S.D. (2025), Normalization strategies for lipidome data in cell line panels, Journal of Chemometrics 39(1): e3636.
- Leegwater H., Zhang Z., Zhang X., Wang X., Hankemeier T., Zweemer J.M., Water B. van de, Danen E.H.J., Hoekstra M., Harms A.C., Kindt A.S.D. & Le Dévédec S.E. (2025), Distinct lipidomic profiles in breast cancer cell lines relate to proliferation and EMT phenotypes, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1870(7): 159679.
- Liu Q., Stel W. van der, Noord V.E. van der, Leegwater H., Coban B., Elbertse K., Pruijs J.T.M., Béquignon O.J.M., Westen G.J.P. van, Dévédec S.E. le & Danen E.H.J. (2022), Hypoxia triggers TAZ phosphorylation in basal a triple negative breast cancer cells, International Journal of Molecular Sciences 23(17): 10119.