Gijs Ruijgrok
Postdoc
- Name
- Dr. G. Ruijgrok
- Telephone
- 071 5272727
- g.ruijgrok@lic.leidenuniv.nl
- ORCID iD
- 0000-0001-9032-4970
Postdoc
- Faculty of Science
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Bio-organic Synthesis
- Ruijgrok G., Offen W.A., Pickles I.B., Raju D., Patsos T., Boer C. de, Ofman T.P., Rompa J., Oord D. van, Dodson E.J., Beekers A., Voskuilen T., Ferrari M., Wu L., Janssen A.P.A., Codee J.D.C., Howell P.L., Davies G.J. & Overkleeft H.S. (2025), Bespoke activity-based probes reveal that the pseudomonas aeruginosa endoglycosidase, PslG, Is an Endo-β-glucanase, Journal of the American Chemical Society 147(10): 8578-8586.
- Ruijgrok G., Wu D., Overkleeft H.S. & Codee J.D.C. (2024), Synthesis and application of bacterial exopolysaccharides, Current Opinion in Chemical Biology 78: 102418.
- Ruijgrok G. (12 September 2024), Inhibitors and probes targeting PslG (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Supervisor(s): Overkleeft H.S. & Codée J.D.C.
- Ofman T.P., Heming J.J.A., Nin-Hill A., Küllmer F., Moran E., Bennett M., Steneker R., Klein A.M., Ruijgrok G., Kok K., Armstrong Z.W.B., Aerts J.M.F.G., Marel G.A. van der, Rovira C., Davies G.J., Artola M.E., Codée J.D.C. & Overkleeft H.S. (2024), Conformational and electronic variations in 1,2‐ and 1,5a‐Cyclophellitols and their impact on retaining α‐glucosidase inhibition, Chemistry: a European Journal 30(31): e202400723.
- Thaler M., Ofman T.P., Kok K., Heming J.J.A., Moran E., Pickles I., Leijs A.A., Nieuwendijk A.M.C.H. van den, Berg R.J.B.H.N. van den, Ruijgrok G., Armstrong Z.W.B., Salgado-Benvindo C., Ninaber D.K., Snijder E.J., Boeckel C.A.A. van, Artola Perez de Azanza M.E., Davies G.J., Overkleeft H.S. & Hemert M.J. van (2024), Epi-Cyclophellitol cyclosulfate, a mechanism-based endoplasmic reticulum α-Glucosidase II inhibitor, blocks replication of SARS-CoV-2 and other coronaviruses, ACS Central Science 10(8): 1594-1608.
- Boer C. de, Armstrong Z.W.B, Lit V.A.J., Barash U., Ruijgrok G., Boyango I., Weitzenberg M.M., Schröder S.P., Sarris A.J.C., Meeuwenoord N.J., Bule P., Kayal Y., Ilan N., Codee J.D.C., Vlodavsky I., Overkleeft H.S., Davies G.J. & Wu L. (2022), Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo, Proceedings of the National Academy of Sciences 119(31): e2203167119.
- Hansen T., Ofman T.P., Vlaming J.G.C., Gagarinov I.A., Beek J. van, Goté T.A., Tichem J.M., Ruijgrok G., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Reactivity-stereoselectivity mapping for the assembly of Mycobacterium marinum lipooligosaccharides, Angewandte Chemie (International Edition) 60(2): 937-945.