Daniel Rozen
Associate professor
- Name
- Dr. D.E. Rozen
- Telephone
- +31 71 527 7990
- d.e.rozen@biology.leidenuniv.nl
- ORCID iD
- 0000-0002-7772-0239
My laboratory uses bacteria in laboratory evolution experiments to study the ecology and genetics of adaptation. We currently have three main research themes. The specific topics addressed are the evolution of bacterial transformation and competence, the causes and consequences of within population phenotypic heterogeneity, and the evolution and ecology of bacteriocins. In addition to our bacterial work, we also study the evolution and ecology of insect-bacterial interactions in the burying beetle Nicrophorus vespilloides.
Postdocs
News
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Healthy soil for a healthy gut -
Collaborating bacteria sacrifice themselves for the greater good -
Researchers tackle antibiotic-resistant bacteria -
Altruism in bacteria: colonies divide the work -
IBL-research interview: Daniel Rozen -
Discoverer of the Year, Best Dissertation and Education prize 2015 -
New insights into the production of antibiotics by bacteria
Associate professor
- Science
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Kasteren S.I. van & Rozen D.E. (2023), Using click chemistry to study microbial ecology and evolution, ISME Communications 3: 9.
- Anonymous (2022), Genome sequence and characterization of Streptomyces phage Pablito, representing a new species within the genus Janusvirus [Genoom sequentie en karakterisatie van streptomyces faag pablito, een nieuwe soort in de genus Janusvirus] (translation: Ongenae V.M.A., Azeredo J., Kropinski A.M., Rozen D.E., Briegel A. & Claessen D. ), Scientific Reports 12: 17785.
- Shitut S.S., Shen M., Claushuis B., Derks R.J.E., Giera M., Rozen D.E., Claessen D. & Kros A. (2022), Generating heterokaryotic cells via bacterial cell-cell fusion, Microbiology Spectrum 10(4): e0169322.
- Ongenae V.M.A., Sidi Mabrouk A., Crooijmans M.E., Rozen D.E., Briegel A. & Claessen D. (2022), Reversible bacteriophage resistance by shedding the bacterial cell wall, Open Biology 12(6): 210379.
- Liakopoulos A., Aulin L.B.S., Buffoni M., Fragkiskou E., Hasselt J.G.C. van & Rozen D.E. (2022), Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution, Proceedings of the National Academy of Sciences 119(18): e2121768119.
- Aulin L.B.S., Liakopoulos A., Graaf P.H. van der, Rozen D.E. & Hasselt J.G.C. (2021), Design principles of collateral sensitivity-based dosing strategies, Nature Communications 12.
- Shitut S., Bergman G.Ö., Kros A., Rozen D.E. & Claessen D. (2020), Use of permanent wall-deficient cells as a system for the discovery of new-to-nature metabolites, Microorganisms 8(12): 1897.
- Westhoff S., Kloosterman A., Hoesel S.F.A. van, Wezel G.P. van & Rozen D.E. (2021), Competition sensing alters antibiotic production in streptomyces, mBio 12.
- Zhang Z., Du C., De Barsy F., Liem M., Liakopoulos A., Wezel G.P. van, Choi Y.H., Claessen D. & Rozen D.E. (2020), Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation, Science Advances 6(3): eaay5781.
- Westhoff S., Otto S.B., Swinkels A., Bode B., Wezel G.P. van & Rozen D.E. (2020), Spatial structure increases the benefits of antibiotic production in Streptomyces, Evolution 74(1): 179-187.
- Wang Y. & Rozen D.E. (2017), Gut Microbiota Colonization and Transmission in the Burying Beetle Nicrophorus vespilloides throughout Development, Applied and Environmental Microbiology 83(9): e03250.
- Westhoff S., Leeuwe T.M. van, Qachach O., Zhang Z., Wezel G.P. van & Rozen D.E. (2017), The evolution of no-cost resistance at sub-MIC concentrations of streptomycin in Streptomyces coelicolor, The ISME journal 11(5): 1168-1178.
- Westhoff S., Wezel G.P. van & Rozen D.E. (2017), Distance-dependent danger responses in bacteria, Current Opinion in Microbiology 36: 95-101.
- Lugtenberg E.J.J., Rozen D.E. & Kamilova F. (2017), Wars between microbes on roots and fruits, F1000Research 6: 343.
- Zhang Z., Claessen D. & Rozen D.E. (2016), Understanding Microbial Divisions of Labor, FRONTIERS IN MICROBIOLOGY 7: 2070.
- Abrudan M.I., Smakman F., Gimbergen A., Westhoff S., Miller E.L., Wezel G.P. van & Rozen D.E. (2015), Socially mediated induction and suppression of antibiosis during bacterial coexistence, Proceedings of the National Academy of Sciences of the United States of America 112(35): 11054–11059.
- Rozen D.E. (2015), A head for sex, Journal of Experimental Biology 218(19): 2984-2985.
- Wolf J.B., Howie J.A., Parkinson K., Gruenheit N., Melo D., Rozen D.E. & Thompson C.R.L. (2015), Fitness trade-offs result in the illusion of social success, CURRENT BIOLOGY 25(8): 1086-1090.
- Rozen D.E. (2015), The dubious motives of generous men, Journal of Experimental Biology 218(13): 1980.
- Rozen D.E. (2015), The invisibility cloak of filefish, Journal of Experimental Biology 218(7): 966-966.
- Jacobs C.G.C., Wang Y., Vogel H., Vilcinskas A., Zee M. van der & Rozen D.E. (2014), Egg survival is reduced by grave-soil microbes in the carrion beetle, Nicrophorus vespilloides, BMC Evolutionary Biology 14: 208.
- Claessen D., Rozen D.E., Kuipers O.P., Søgaard-Andersen L. & Wezel G.P. van (2014), Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies, Nature Reviews Microbiology 12(2): 115-124.
- Rozen D.E. (2013), A mother's secret password, Journal of Experimental Biology 216 (7): v-v.
- Arce A.N., Smiseth P.T. & Rozen D.E. (2013), Antimicrobial secretions and social immunity in larval burying beetles, Nicrophorus vespilloides, Animal Behaviour 86 (4): 741-745.
- Rozen D.E. (2013), Birds' digestion cleanses passing seeds, Journal of Experimental Biology 216 (19): v-vi.
- Engelmoer D.J.P., Donaldson I. & Rozen D.E. (2013), Conservative Sex and the Benefits of Transformation in Streptococcus pneumoniae, PLOS PATHOGENS 9 (11), e10037581.
- Rozen D.E. (2013), Parasites and the great divide, Journal of Experimental Biology 216 (2): vi-vi.
- Evans B.A. & Rozen D.E. (2013), Significant variation in transformation frequency in Streptococcus pneumoniae, ISME Journal 7 (4): 791-799.
- Rozen D.E. (2013), The electrifying buzz of bees, Journal of Experimental Biology 216 (12): iv-iv.
No relevant ancillary activities