Education and Research Staff Member
I work as a Facility Manager Bioinformatics, representing the new Bioinformatic facility at the IBL, together with Roxane Boyer. I facilitate bioinformatic analyses within the institute by organizing the infrastructure and providing guidance on the implementation and execution of specific tasks. This includes for instance help with access to servers, help with scripting or the analysis itself.
With a background in biology (PhD in phylogenetics) my bioinformatics expertise started with comparative genomics and systematics, but later also included more general omics analysis, including transcriptomics, metagenomics and genome-scale models. Currently I am also interested in expanding this to motif searching, phylogenetic footprinting and more in general visualization and representation of results, for instance using R.
Griffen AL, Beall CJ, Firestone ND, Gross EL, Difranco JM, Hardman JH, Vriesendorp B, Faust RA, Janies DA, Leys EJ. CORE: a phylogenetically-curated 16S rDNA database of the core oral microbiome. PLoS One. 2011 Apr 22;6(4):e19051. doi: 10.1371/journal.pone.0019051. PMID: 21544197; PMCID: PMC3081323.
van der Pol E, Springer J, Vriesendorp B, Weusthuis R, Eggink G. Precultivation of Bacillus coagulans DSM2314 in the presence of furfural decreases inhibitory effects of lignocellulosic by-products during L(+)-lactic acid fermentation. Appl Microbiol Biotechnol. 2016 Dec;100(24):10307-10319. doi: 10.1007/s00253-016-7725-z. Epub 2016 Jul 27. PMID: 27464829; PMCID: PMC5119848.
My background is in biosystematics and bioinformatics and worked mainly with plants and industrial food bacteria. Prior to this position she worked as a bioinformatician within biotech company Corbion, mainly focusing on lactic-acid producing bacteria and fungi. She has also experience in teaching, at secondary schools and at the Marine institute of Quelimane, Mozambique, where she taught classes on phycology and biosystematics. Bastienne obtained her PhD in phylogenetics from Wageningen University and did a postdoc in Columbus, Ohio at the Dentistry Department of the Ohio State University, linking oral bacteria to diseases.
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