Barend Mons
Professor Biosemantics
- Name
- Prof.dr. B. Mons
- Telephone
- +31 71 526 9111
- b.mons@lumc.nl
- ORCID iD
- 0000-0003-3934-0072
Barend Mons is professor in Biosemantics at the LUMC and also a board member of the Leiden Centre of Data Science. He is one of the founders of the FAIR principles for Open Science and the concept of Data Stewardship. In 2015 he was the chair of the High Level Expert Group of the European Commission on the European Open Science Cloud. he is currently the scientific director of the international office of GO FAIR, situated in the ‘Poortgebouw’ building of the LUMC campus.
Barend Mons is professor in Biosemantics at the LUMC and also a board member of the Leiden Centre of Data Science. He is one of the founders of the FAIR principles for Open Science and the concept of Data Stewardship. In 2015 he was the chair of the High Level Expert Group of the European Commission on the European Open Science Cloud. he is currently the scientific director of the international office of GO FAIR, situated in the ‘Poortgebouw’ building of the LUMC campus.
Biosemantics
Biosemantics is a new approach characterised by computer-assisted knowledge discovery. With this approach machines can perform close to associative ‘thinking’ This line is now stongly routed in the Dutch National Science Agenda.
Academic career
Barend Mons did his PhD in Leiden (1986). His dissertation was on basic biology and genetics of malaria parasites. He continued this line of research for over a decade in Leiden and at TNO. After periods at the European Commission and in industry, Barend returned to Leiden, where his inaugural speech, accepting the chair in Bisoemantics was held at 25-02-2013. The title of his inaugural lecture was ‘Knowledge is like Love….it multiplies when shared’.
Prizes and honourable appointments
Barend received the Eyckman medal for his research in Malaria and is a member of numerous international scientific boards.
Global Open FAIR initiative
The Global Open FAIR initiative is a rapidly expanding international consortium, aimed at the Internet of FAIR data and Services, initially supported by the Dutch, the German and the French governments.
Professor Biosemantics
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Analytical Biosciences
Professor Biosemantics
- Faculteit Geneeskunde
- Divisie 4
- Humane Genetica
- César H. Bernabé, Lieze Thielemans, Rajaram Kaliyaperumal, Claudio Carta, Shuxin Zhang, Celia W.G. van Gelder, Nirupama Benis, Luiz Olavo Bonino da Silva Santos, Ronald Cornet, Bruna dos Santos Vieira, Nawel Lalout, Ines Henriques, Alberto Cámara Ballesteros, Kees Burger, Martijn G. Kersloot, Friederike Ehrhart, Esther van Enckevort, Chris T. Evelo, Alasdair J. G. Gray, Marc Hanauer, Kristina Hettne, Joep de Ligt, Arnaldo Pereira, Núria Queralt-Rosinach, Erik Schultes, Domenica Taruscio, Andra Waagmeester, Mark D. Wilkinson, Egon L. Willighagen, Mascha Jansen, Barend Mons, Marco Roos & Annika Jacobsen (2023), Building expertise on FAIR through evolving Bring Your Own Data (BYOD) workshops, Data Intelligence.
- Bernabé, C.H.; Queralt-Rosinach, N.; Souza, V.E.S.; Santos, L.O.B.D.; Mons, B.; Jacobsen, A. & Roos, M. (2023), The use of foundational ontologies in biomedical research, Journal of Biomedical Semantics 14(1).
- Schultes E., Roos M., Santos L.O.B.D., Guizzardi G., Bouwman J., Hankemeier T., Baak A. & Mons B. (2022), FAIR digital twins for data-intensive research, Frontiers in Big Data 5: 883341.
- Schultes, E.; Roos, M.; Santos, L.O.B.D.; Guizzardi, G.; Bouwman, J.; Hankemeier, T.; Baak, A. & Mons, B. (2022), FAIR Digital Twins for Data-Intensive Research, Frontiers in Big Data 5.
- Queralt-Rosinach, N.; Kaliyaperumal, R.; Bernabe, C.H.; Long, Q.Q.; Joosten, S.A.; Wijk, H.J. van der; Flikkenschild, E.L.A.; Burger, K.; Jacobsen, A.; Mons, B.; Roos, M.; BEAT COVID Grp & COVID-19 LUMC Grp (2022), Applying the FAIR principles to data in a hospital: challenges and opportunities in a pandemic, Journal of Biomedical Semantics 13(1).
- Mons, B. (2020), Invest 5% of research funds in ensuring data are reusable, Nature 578(7796): 491-491.
- Mons, B. (2020), The VODAN IN, European Journal of Human Genetics 28(6): 724-727.
- Wilkinson, M.D.; Dumontier, M.; Aalbersberg, I.J.; Appleton, G.; Axton, M.; Baak, A.; Blomberg, N.; Boiten, J.W.; Santos, L.B.D.; Bourne, P.E.; Bouwman, J.; Brookes, A.J.; Clark, T.; Crosas, M.; Dillo, I.; Dumon, O.; Edmunds, S.; Evelo, C.T.; Finkers, R.; Gonzalez-Beltran, A.; Gray, A.J.G.; Groth, P.; Goble, C.; Grethe, J.S.; Heringa, J.; Hoen, P.A.C.'.; Hooft, R.; Kuhn, T.; Kok, R.; Kok, J.; Lusher, S.J.; Martone, M.E.; Mons, A.; Packer, A.L.; Persson, B.; Rocca-Serra, P.; Roos, M.; Schaik, R. van; Sansone, S.A.; Schultes, E.; Sengstag, T.; Slater, T.; Strawn, G.; Swertz, M.A.; Thompson, M.; Lei, J. van der; Mulligen, E. van; Velterop, J.; Waagmeester, A.; Wittenburg, P.; Wolstencroft, K.; Zhao, J. & Mons, B. (2019), The FAIR Guiding Principles for scientific data management and stewardship (vol 15, 160018, 2016).
- Verhaart, I.E.C.; Hoen, P.A.C. 't; Roos, M.; Vroom, E.; Mons, B.; Isla, J.; Ludena, Y.; Goemans, N.; Campbell, C.; Niks, E.; Guglieri, M.; Evangelista, T.; Furlong, P.; Montolio, M.; Fegan, G.; Johnson, A.; Zito, I.; Athanasiou, D.; Franken, M.; Neven, F.K.; Bergsma, A.; Lamy, F.; Hofmeister, S.; Gumus, G.; Stoyanova, V.; Spitali, P.; Meijer-Krom, Y.; Godfrey, J.; Escalera, B.N.; Tournavitis, G.; Bakker, S.A.; Paliouras, G.; Delage, A.; Berrens, M.; Anderton, M.; Bergman, A. & Workshop Participants (2019), Meeting on data sharing for Duchenne 21-22 March 2019 Amsterdam, the Netherlands, Neuromuscular Disorders 29(10): 800-810.
- Gelder, C.W.G. van; Hooft, R.W.W.; Rijswijk, M.N. van; Berg, L. van den; Kok, R.G.; Reinders, M.; Mons, B. & Heringa, J. (2019), Bioinformatics in the Netherlands: the value of a nationwide community, Briefings in Bioinformatics 20(2): 375-383.
- Gool, A.J. van; Bietrix, F.; Caldenhoven, E.; Zatloukal, K.; Scherer, A.; Litton, J.E.; Meijer, G.; Blomberg, N.; Smith, A.; Mons, B.; Heringa, J.; Koot, W.J.; Smit, M.J.; Hajduch, M.; Rijnders, T. & Ussi, A. (2017), Bridging the translational innovation gap through good biomarker practice, Nature Reviews Drug Discovery 16(9): 587-+.
- Mina, E.; Roon-Mom, W. van; Hettne, K.; Zwet, E. van; Goeman, J.; Neri, C.; Hoen, P.A.C. 't; Mons, B. & Roos, M. (2016), Common disease signatures from gene expression analysis in Huntington's disease human blood and brain, Orphanet Journal of Rare Diseases 11.
- Wilkinson, M.D.; Dumontier, M.; Aalbersberg, I.J.; Appleton, G.; Axton, M.; Baak, A.; Blomberg, N.; Boiten, J.W.; Santos, L.B.D.; Bourne, P.E.; Bouwman, J.; Brookes, A.J.; Clark, T.; Crosas, M.; Dillo, I.; Dumon, O.; Edmunds, S.; Evelo, C.T.; Finkers, R.; Gonzalez-Beltran, A.; Gray, A.J.G.; Groth, P.; Goble, C.; Grethe, J.S.; Heringa, J.; Hoen, P.A.C. 't; Hooft, R.; Kuhn, T.; Kok, R.; Kok, J.; Lusher, S.J.; Martone, M.E.; Mons, A.; Packer, A.L.; Persson, B.; Rocca-Serra, P.; Roos, M.; Schaik, R. van; Sansone, S.A.; Schultes, E.; Sengstag, T.; Slater, T.; Strawn, G.; Swertz, M.A.; Thompson, M.; Lei, J. van der; Mulligen, E. van; Velterop, J.; Waagmeester, A.; Wittenburg, P.; Wolstencroft, K.; Zhao, J. & Mons, B. (2016), Comment: The FAIR Guiding Principles for scientific data management and stewardship, Scientific Data 3.
- Hettne, K.M.; Thompson, M.; Haagen, H.H.H.B.M. van; Horst, E. van der; Kaliyaperumal, R.; Mina, E.; Tatum, Z.; Laros, J.F.J.; Mulligen, E.M. van; Schuemie, M.; Aten, E.; Li, T.S.; Bruskiewich, R.; Good, B.M.; Su, A.I.; Kors, J.A.; Dunnen, J. den; Ommen, G.J.B. van; Roos, M.; Hoen, P.A. 't; Mons, B. & Schultes, E.A. (2016), The Implicitome: A Resource for Rationalizing Gene-Disease Associations, PLoS ONE 11(2).
- Mina, E.; Thompson, M.; Kaliyaperumal, R.; Zhao, J.; Horst, E. van der; Tatum, Z.; Hettne, K.M.; Schultes, E.A.; Mons, B. & Roos, M. (2015), Nanopublications for exposing experimental data in the life-sciences: a Huntington's Disease case study, Journal of Biomedical Semantics 6.
- Marti-Solano, M.; Birney, E.; Bril, A.; Pasqua, O. della; Kitano, H.; Mons, B.; Xenarios, I. & Sanz, F. (2014), Integrative knowledge management to enhance pharmaceutical R&D, Nature Reviews Drug Discovery 13(4): 239-240.
- Masseroli, M.; Mons, B.; Bongcam-Rudloff, E.; Ceri, S.; Kel, A.; Rechenmann, F.; Lisacek, F. & Romano, P. (2014), Integrated Bio-Search: challenges and trends for the integration, search and comprehensive processing of biological information, BMC Bioinformatics 15.
- Oetting, W.S.; Robinson, P.N.; Greenblatt, M.S.; Cotton, R.G.; Beck, T.; Carey, J.C.; Doelken, S.C.; Girdea, M.; Groza, T.; Hamilton, C.M.; Hamosh, A.; Kerner, B.; MacArthur, J.A.L.; Maglott, D.R.; Mons, B.; Rehm, H.L.; Schofield, P.N.; Searle, B.A.; Smedley, D.; Smith, C.L.; Bernstein, I.T.; Zankl, A. & Zhao, E.Y. (2013), Getting Ready for the Human Phenome Project: The 2012 Forum of the Human Variome Project, Human Mutation 34(4): 661-666.
- Haagen, H.H.H.B.M. van; Hoen, P.A.C. 't; Mons, B. & Schultes, E.A. (2013), Generic Information Can Retrieve Known Biological Associations: Implications for Biomedical Knowledge Discovery, PLoS ONE 8(11).
- Cases, M.; Furlong, L.I.; Albanell, J.; Altman, R.B.; Bellazzi, R.; Boyer, S.; Brand, A.; Brookes, A.J.; Brunak, S.; Clark, T.W.; Gea, J.; Ghazal, P.; Graf, N.; Guigo, R.; Klein, T.E.; Lopez-Bigas, N.; Maojo, V.; Mons, B.; Musen, M.; Oliveira, J.L.; Rowe, A.; Ruch, P.; Shabo, A.; Shortliffe, E.H.; Valencia, A.; Lei, J. van der; Mayer, M.A. & Sanz, F. (2013), Improving data and knowledge management to better integrate health care and research, Journal of Internal Medicine 274(4): 321-328.
- Dalgleish, R.; Molero, E.; Kidd, R.; Jansen, M.; Past, D.; Robl, A.; Mons, B.; Diaz, C.; Mons, A. & Brookes, A.J. (2012), Solving Bottlenecks in Data Sharing in the Life Sciences, Human Mutation 33(10): 1494-1496.
- Patrinos, G.P.; Cooper, D.N.; Mulligen, E. van; Gkantouna, V.; Tzimas, G.; Tatum, Z.; Schultes, E.; Roos, M. & Mons, B. (2012), Microattribution and nanopublication as means to incentivize the placement of human genome variation data into the public domain, Human Mutation 33(11): 1503-1512.
- Williams, A.J.; Harland, L.; Groth, P.; Pettifer, S.; Chichester, C.; Willighagen, E.L.; Evelo, C.T.; Blomberg, N.; Ecker, G.; Goble, C. & Mons, B. (2012), Open PHACTS: semantic interoperability for drug discovery, Drug Discovery Today 17(21-22): 1188-1198.
- Harmelen, F. van; Kampis, G.; Borner, K.; Besselaar, P. van den; Schultes, E.; Goble, C.; Groth, P.; Mons, B.; Anderson, S.; Decker, S.; Hayes, C.; Buecheler, T. & Helbing, D. (2012), Theoretical and technological building blocks for an innovation accelerator, European Physical Journal - Special Topics 214(1): 183-214.
- Mons, B.; Haagen, H. van; Chichester, C.; Hoen, P.B. 't; Dunnen, J.T. den; Ommen, G. van; Mulligen, E. van; Singh, B.; Hooft, R.; Roos, M.; Hammond, J.; Kiesel, B.; Giardine, B.; Velterop, J.; Groth, P. & Schultes, E. (2011), The value of data, Nature Genetics 43(4): 281-283.
- Haagen, H.H.H.B.M. van; Hoen, P.A.C. 't; Morree, A. de; Roon-Mom, W.M.C. van; Peters, D.J.M.; Roos, M.; Mons, B.; Ommen, G.J. van & Schuemie, M.J. (2011), In silico discovery and experimental validation of new protein-protein interactions., Proteomics 11(5): 843-53.
- van Haagen H & Mons B (2011), In silico knowledge and content tracking., Methods in Molecular Biology 760: 129-40.
- van Haagen HHHBM, 't Hoen PAC, Bovo AB, de Morree A, van Mulligen EM, Chichester C, Kors JA, den Dunnen JT, van Ommen GJB, van der Maarel SM, Kern VM, Mons B & Schuemie MJ (2009), Novel Protein-Protein Interactions Inferred from Literature Context, PLoS ONE 4(11).
- van Haagen HH, 't Hoen PA, Botelho Bovo A, de Morrée A, van Mulligen EM, Chichester C, Kors JA, den Dunnen JT, van Ommen GJ, van der Maarel SM, Kern VM, Mons B & Schuemie MJ (2009), Novel protein-protein interactions inferred from literature context., PLoS ONE 4(11): e7894.
- Mons B, Ashburner M, Chichester C, van Mulligen E, Weeber M, den Dunnen J, van Ommen GJ, Musen M, Cockerill M, Hermjakob H, Mons A, Packer A, Pacheco R, Lewis S, Berkeley A, Melton W, Barris N, Wales J, Meijssen G, Moeller E, Roes PJ, Borner K & Bairoch A (2008), Calling on a million minds for community annotation in WikiProteins, Genome Biology 9(5).
- Jelier R, 't Hoen PAC, Sterrenburg E, den Dunnen JT, van Ommen GJB, Kors JA & Mons B (2008), Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease, BMC Bioinformatics 9.
- Schuemie M, Chichester C, Lisacek F, Coute Y, Roes PJ, Sanchez JC, Kors J & Mons B (2007), Assignment of protein function and discovery of novel nucleolar proteins based on automatic analysis of MEDLINE, Proteomics 7(6).
- Voorzitter (1 dag/wk buiten LUMC/UL aanstelling)