Universiteit Leiden

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Research project

Reconstruction and Computational Modelling for Inherited Metabolic Diseases

Accelerating the diagnosis and personalising the management of inherited metabolic diseases.

2023 - 2027
Amy Harms

Key features of Recon4IMD

  • Overall objectives: Accelerate diagnosis and personalise management of inherited metabolic diseases.

  • Primary output: Clinically validated decision support tools enabling accelerated diagnosis and personalised management of inherited metabolic diseases, based on genomic, proteomic, and metabolomic data-driven computational models.

  • Sustainability: Development of academic technology to meet medical regulatory standards and a roadmap for exploitation within a European foundation to aid personalised diagnosis and management of inherited metabolic diseases.

  • Implemented by: A group of world-class scientists and clinicians from a diversity of disciplines who have collaborated multiple times and have a track record of leading key national and EU-funded initiatives to deliver high-impact results.


Recon4IMD is co-funded by the European Union's Horizon Europe Framework Programme (grant number 101080997), the Swiss State Secretariat for Education, Research and Innovation, and by United Kingdom Research and Innovation.

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