Dissertation
Applications for DNA-encapsulated silver clusters in physics, biology and medicine
We use DNA strands to stabilize few-atom silver clusters, which show unique optical and chemical properties. This thesis involves the study of these constructs for various applications.
- Author
- D. de Bruin
- Date
- 29 October 2024
- Links
- Thesis in Leiden Repository
We analyze the structures as optical emitters, finding uses for them in biosensing, including performing measurements on live cell interiors, and analysis of DNA hybridization dynamics. Secondly, we use the metal to create short range interaction schemes for the purpose of measuring distances on the nanometer scale. Finally, we find applications for DNA-metal hybrids in therapeutics, introducing a novel method to kill cancer cells which shows a unique potential for precision treatments.