Yi Ding
PhD candidate / guest
- Name
- Dr. Y. Ding
- Telephone
- +31 71 527 2727
- y.ding@biology.leidenuniv.nl
Yi Ding’s research focuses on understanding how transcriptomics and metabolomics are affected by an obese gene called leptin and mycobacterial infection which results in tuberculosis. For this, zebrafish, as an animal model, and multidisciplinary approaches from biology, chemistry and bioinformatics are used.
Publications
Ding, Y., Raterink, R., Marín-Juez, R. et al. Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae. Sci Rep 10, 11635 (2020). https://doi.org/10.1038/s41598-020-68443-y
PhD candidate / guest
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
Postdoc
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
- Eeza M.N.H., Singer R., Ding Y., He J., Zuberi Z., Baelde H.J., Groot H.J.M. de, Matysik J., Spaink H.P. & Alia A. (2023), Probing microstructural changes in muscles of leptin-deficient zebrafish by non-invasive ex-vivo magnetic resonance microimaging, PLoS ONE 18(4): e0284215.
- Hu W., Liu L., Forn-Cuní G., Ding Y., Alia A. & Spaink H.P. (2023), Transcriptomic and metabolomic studies reveal that toll-like receptor 2 has a role in glucose-related metabolism in unchallenged zebrafish larvae (Danio rerio), Biology 12(2): 323.
- Ding Y., Haks M.C., Eeden S.J.F. van den, Ottehoff T.H.M., Harms A.C., Hankemeier T., Eeza M.N.H., Matysik J., Alia A. & Spaink H.P. (2022), Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome, Metabolomics 18(8): 67.
- Ding Y. (7 December 2021), Functions of leptin in tuberculosis and diabetes: multi-omics studies across species (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Supervisor(s): Spaink H.P. & Alia A.
- Ding Y., Haks M.C., Forn Cuní G., He J., Nowik N., Harms A.C., Hankemeier T., Eeza M.N.H., Matysik J., Alia A. & Spaink H.P. (2021), Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathways, Cell & Bioscience 11(1): 126.
- He J., Ding Y., Nowik N., Jager C., Eeza M.N.H., Alia A., Baelde H.J. & Spaink H.P. (2021), Leptin deficiency affects glucose homeostasis and results in adiposity in zebrafish, Journal of Endocrinology 249(2): 125-134.
- Ding Y. Raterink R. Marín‑Juez R. Veneman W.J. Egbers K. Eeden S. van den Haks M.C. Joosten S.A. Ottenhof T.H.M. Harms A.C. Alia A. Hankemeier T. Spaink H.P. (2020), Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria‑infected mice and zebrafish larvae, Scientific Reports 10: 11635.
No relevant ancillary activities