Rawi Ramautar
Director of Education / Associate Professor
- Name
- Dr. R. Ramautar
- Telephone
- +31 71 527 4509
- r.ramautar@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0002-1673-4848
More information about Rawi Ramautar
News
Former PhD Candidates
- H-index (April 2019): 33
- Total number of citations (April 2019): 2414
- Total number of scientific publications (April 2019): 70
- Editor of Microchemical Journal (Elsevier)
- Editor of book Capillary Electrophoresis-Mass Spectrometry for Metabolomics (Royal Society of Chemistry, 2018)
- NWO Veni laureate (2013)
- NWO Vidi laureate (2016)
- Main scientific achievement: Development of a low-flow capillary electrophoresis-mass spectrometry platform for ultrasensitive profiling of metabolites in low amounts of biological sample.
- Main teaching achievement: Training MSc students in grant writing (Veni level) in context of analytical method development in drug discovery and metabolomics
Director of Education / Associate Professor
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Analytical Biosciences
- Mever M. van, Mamani-Huanca M., Faught L.E., Lopez-Gonzalvez A., Hankemeier T., Barbas C., Schaaf M.J.M. & Ramautar R. (2024), Application of a capillary electrophoresis-mass spectrometry metabolomics workflow in zebrafish larvae reveals new effects of cortisol, Electrophoresis 45(5-6): 380-391.
- Wevers D., Ramautar R., Clark C.P., Hankemeier T. & Ali A.M.A.M. (2023), Opportunities and challenges for sample preparation and enrichment in mass spectrometry for single‐cell metabolomics, Electrophoresis 44(24): 2000-2024.
- He Y., Mever M. van, Yang W., Huang L.: Ramautar R., Rijksen Y., Vermeij W.P., Hoeijmakers J.H.J., Harms A.C., Lindenburg P.W. & Hankemeier T. (2022), A sample preparation method for the simultaneous profiling of signaling lipids and polar metabolites in small quantities of muscle tissues from a mouse model for sarcopenia, Metabolites 12(8): 742.
- Mever M. van, Fabjanowicz M., Mamani-Huanca M., Lopez-Gonzalvez A., Plotka-Wasylka J. & Ramautar R. (2022), Profiling of polar ionogenic metabolites in Polish wines by capillary electrophoresis-mass spectrometry, Electrophoresis 43(18-19): 1814-1821.
- He B.S., Di X., Gulded F., Harder A.V.E., Maagdenberg A.M.J.M. van den, Terwindt G.M., Krekels E.H.J., Kohler I., Harms A.C., Ramautar R. & Hankemeier T. (2022), Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method, Analytica Chimica Acta 1210: 339888.
- Mever M. van, Segers K., Mangelings D., Hankemeier T., Heyden Y. vander, Eeckhaut A. van & Ramautar R. (2021), Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: actual status and the way forward, Trends in Analytical Chemistry 143: 116365.
- He B.S., Zhang W., Guled F., Harms A.C., Ramautar R. & Hankemeier T. (2021), Analytical techniques for biomass-restricted metabolomics: an overview of the state-of-the-art, Microchemical Journal 171: 106794.
- Mever M. van, Willacey C.C.W., Zhang W., Drouin N.F.P., Christina A.E., Lindenburg P.W., Veldhoven J.P. D. van, Es D. van der, Harms A.C., Hankemeier T. & Ramautar R. (2021), Profiling acidic metabolites by capillary electrophoresis‐mass spectrometry in low numbers of mammalian cells using a novel chemical derivatization approach, Analytical Science Advances 3(1-2): 3-13.
- Segers K.R.H., Zhang W., Aourz N., Bongaerts J., Declerck S., Mangelings D., Hankemeier T., Bundel D. de, Heyden Y. van der, Smolders I., Ramautar R. & Eeckhaut A. van (2020), CE-MS metabolic profiling of volume-restricted plasma samples from an acute mouse model for epileptic seizures to discover potentially involved metabolomic features, Talanta 217: 121107.
- Mever M. van, Segers K.R.H., Drouin N.F.P., Guled F., Vander Heyden Y., Van Eeckhaut A., Hankemeier T. & Ramautar R. (2020), Direct profiling of endogenous metabolites in rat brain microdialysis samples by capillary electrophoresis-mass spectrometry with on-line preconcentration, Microchemical Journal 156: 104949.
- Zhang W., Guled F., Hankemeier T. & Ramautar R. (2020), Profiling nucleotides in low numbers of mammalian cells by sheathless CE-MS in positive ion mode: Circumventing corona discharge, Electrophoresis 41(5-6): 360-369.
- Drouin N.F.P., Mever M. van, Zhang W., Tobolkina E., Ferre S., Servais A.C., Gou M.J., Nyssen L., Fillet M., Lageveen-Kammeijer G.S.M., Nouta J., Chetwynd A.J., Lynch I., Thorn J.A., Meixner J., Lossner C., Taverna M., Liu S., Tran N.T., Francois Y., Lechner A., Nehm R., Banni G.A.D., Nasreddine R., Colas C., Lindner H.H., Faserl K., Neususs C., Nelke M., Lammerer S., Perrin C., Bich-Muracciole C., Barbas C., Lopez Gonzalvez A., Guttman A., Szigeti M., Britz-McKibbin P., Kroezen Z., Shanmuganathan M., Nemes P., Portero E.P., Hankemeier T., Codesido S., Gonzalez-Ruiz V., Rudaz S. & Ramautar R. (2020), Capillary electrophoresis-mass spectrometry at trial by Metabo-Ring: Effective electrophoretic mobility for reproducible and robust compound annotation, Analytical Chemistry 92(20): 14103-14112.
- Zhang W., Guled F., Hankemeier T. & Ramautar R. (2019), Utility of sheathless capillary electrophoresis-mass spectrometry for metabolic profiling of limited sample amounts, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1105: 10-14.
- Zhang W., Segers K.R.H., Mangelings D., Eeckhaut A. van, Hankemeier T., Heyden Y. van der & Ramautar R. (2019), Assessing the suitability of capillary electrophoresis-mass spectrometry for biomarker discovery in plasma-based metabolomics, Electrophoresis 40(18-19): 2309-2320.
- Mever M. van, Hankemeier T. & Ramautar R. (2019), CE-MS for anionic metabolic profiling: An overview of methodological developments, Electrophoresis 40(18-19): 2349-2359.
- Rossetto Burgos R.C., Ramautar R., Wijk E.P.A. van, Hankemeier T., Greef J. van der & Mashaghi Tabari A. (2018), Pharmacological targeting of ROS reaction network in myeloid leukemia cells monitored by ultra-weak photon emission, OncoTarget 9(2): 2028-2034.
- Rossetto Burgos R.C., Schoeman J.C., Van Winden L.J., Červinková K., Ramautar R., Van Wijk E.P.A., Cifra M., Berger R., Hankemeier T. & Van der Greef J. (2017), Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism, Scientific Reports 7: 1229.
- Rossetto Burgos R.C., Zhang W., Wijk E.P.A. van., Hankemeier T., Ramautar R. & Greef J. van der (2017), Cellular glutathione levels in HL-60 cells during respiratory burst are not correlated with ultra-weak photon emission, Journal of Photochemistry and Photobiology B: Biology 175: 291-296.
- Zhang W., Hankemeier T. & Ramautar R. (2016), Next-generation capillary electrophoresis-mass spectrometry approaches in metabolomics, Current Opinion in Biotechnology 43: 1-7.
- Gulersonmez M.C., Lock S., Hankemeier T. & Ramautar R. (2016), Sheathless capillary electrophoresis-mass spectrometry for anionic metabolic profiling, Electrophoresis 37(7-8): 1007-1014.
- Oedit A., Ramautar R., Hankemeier T. & Lindenburg P.W. (2016), Electroextraction and electromembrane extraction: Advances in hyphenation to analytical techniques, Electrophoresis 37(9): 1170-1186.
- Rossetto-Burgoss R.C., Cervinkova K., Laan T. van der, Ramautar R., Wijk E.P.A., Cifra M., Koval V.V., Berger R., Hankemeier T. & Greef J. van der (2016), Tracking biochemical changes correlated with ultra-weak photon emission using metabolomics, Journal of Photochemistry and Photobiology B: Biology 163: 237-245.
- Zhang Wei, Can Gulersonmez M., Hankemeier Thomas & Ramautar Rawi (2016), Sheathless Capillary Electrophoresis–Mass Spectrometry for Metabolic Profiling of Biological Samples, Journal of visualized experiments (116): e54535.
- Oedit A., Vulto P., Ramautar R., Lindenburg P.W. & Hankemeier T. (2015), Lab-on-a-Chip hyphenation with mass spectrometry: strategies for bioanalytical applications, Current Opinion in Biotechnology 31: 79-85.
- Raterink R., Witkam Y., Vreeken R., Ramautar R. & Hankemeier T. (2014), Gas pressure assisted microliquid-liquid extraction coupled online to direct infusion mass spectrometry: a new automated screening platform for bioanalysis, Analytical Chemistry 86(20): 10323-10330.