Martijn van der Lienden
Postdoc
- Name
- Dr. M.J.C. van der Lienden
- Telephone
- 071 5272727
- m.j.c.van.der.lienden@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-6458-1479
Postdoc
- Faculty of Science
- LIC
- Chemistry for Human Health
- Macromolecular Biochemistry
- Louwerse G.A.M., Bila K., Lienden M.J.C. van der, Beaufort A.J.M. de, Boot R.G., Artola Perez de Azanza M.E., Eijk M.C. van & Aerts J.M.F.G. (2025), Cultured macrophage models for the investigation of lysosomal Glucocerebrosidase and Gaucher Disease, International Journal of Molecular Sciences 26(6): 2726.
- Eskes E.C.B., Dussen L. van, Aerts J.M.F.G., Lienden M.J.C. van der, Maas M., Akkerman E.M., Kuilenburg A.B.P. van, Sjouke B. & Hollak C.E.M. (2024), Acid sphingomyelinase deficiency and Gaucher disease in adults: Similarities and differences in two macrophage storage disorders, JIMD Reports 65(5): 330-340.
- Eskes E.C.B, Lienden M.J.C. van der, Sjouke B., Vliet L. van, Brands M.M.M.G., Hollak C.E.M. & Aerts J.M.F.G. (2023), Glycoprotein non-metastatic protein B (GPNMB) plasma values in patients with chronic visceral acid sphingomyelinase deficiency, Molecular Genetics and Metabolism 139(4): 107631.
- Cabasso O., Kuppuramalingam A., Lelieveld L.T., Lienden M.J.C. van der, Boot R.G., Aerts J.M.F.G. & Horowitz M. (2023), Animal models for the study of Gaucher disease, International Journal of Molecular Sciences 24(22): 16035.
- Lienden M.J.C. van der, Aten J., Boot R.G., Eijk M.C. van, Aarts J.M.F.G. & Kuo C.L. (2022), HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity, Journal of Cellular Biochemistry 123(5): 893-905.
- Lienden M.J.C. van der (18 March 2021), Investigations on the role of impaired lysosomes of macrophages in disease (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Aerts J.M.F.G., Eijk M. van.
- Lienden M.J.C. van der, Aten J., Marques A.R.A., Waas I.S.E., Larsen P.W.B., Claessen N., Wel N.N. van der, Ottenhoff R., Eijk M.C. van & Aerts J.M.F.G. (2021), GCase and LIMP2 abnormalities in the liver of Niemann Pick type C mice, International Journal of Molecular Sciences 22(5): 2532.
- Eskes E.C.B., Lienden M.J.C. van der, Roelofs J.J.T.H., Vogt L., Aerts J.M.F.G., Aten J. & Hollak C.E.M. (2021), Renal involvement in a patient with the chronic visceral subtype of acid sphingomyelinase deficiency resembles Fabry disease, Journal of Inherited Metabolic Disease Reports 62(1): 15-21.
- Bakkum T., Heemskerk M.T., Bos E., Groenewold G.J.M., Oikonomeas-Koppasis N., Walburg K.V., Veen S. van, Lienden M.J.C. van der, Leeuwen T. van, Haks M.C., Ottenhoff T.H.M., Koster A.J. & Kasteren S.I. van (2020), Bioorthogonal correlative light-electron microscopy of mycobacterium tuberculosis in macrophages reveals the effect of antituberculosis drugs on subcellular bacterial distribution, ACS Central Science 6(11): 1997-2007.
- Meel E. van, Bos E., Lienden M.J.C. van der, Overkleeft H.S., Kasteren S.I. van, Koster A.J. & Aerts J.M.F.G. (2019), Localization of Active Endogenous and Exogenous GBA by Correlative Light-Electron Microscopy in Human Fibroblasts, Traffic 20(5): 346-356.
- Aerts J.M.F.G., Kuo C.L., Lelieveld L.T., Boer D.E.C., Lienden M.J.C. van der, Overkleeft H.S. & Artola M. (2019), Glycosphingolipids and lysosomal storage disorders as illustrated by gaucher disease, Current Opinion in Chemical Biology 53: 204-215.
- Tol M.J., Lienden M.J.C. van der, Gabriel T.L., Hagen J.J., Scheij S., Veenendaal T., Klumperman J., Donker-Koopman W.E., Verhoeven A.J., Overkleeft H.S., Aerts J.M.F.G., Argmann C.A. & Eijk M.C. van (2018), HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution, Autophagy 14(3): 437-449.
- Artola M., Kuo C.L., McMahon S.A., Oehler V., Hansen T., Lienden M.J.C. van der, He X., Elst H. van den, Florea B.I., Kermode A.R., Marel G.A. van der, Gloster T.M., Codée J.D.C., Overkleeft H.S. & Aerts J.M.F.G. (2018), New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes, Chemistry: a European Journal 24(71): 19081-19088.
- Lienden M.J.C. van der, Gaspar P., Boot R.G., Aerts J.M.F.G. & Eijk M.C. van (2018), Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages, International Journal of Molecular Sciences 20(1): 66.
- Aerts J.M.F.G., Guimaraes da Lomba Ferraz M.J., Mirzaian M., Gaspar P., Oussoren S.V., Wisse P., Kuo C.L., Lelieveld L.T., Kytidou K., Hazeu M.D., Boer D.E.C., Meijer R., Lienden M.J.C. van der, Herrera D., Gabriel T.L., Aten J., Overkleeft H.S., Eijk M.C. van, Boot R.G. & Rosa Alcalde Marques A. (2017), Lysosomal Storage Diseases. For Better or Worse: Adapting to Defective Lysosomal Glycosphingolipid Breakdown. In: , eLS. eLS: John Wiley & Sons, Ltd.. 1-13.