Universiteit Leiden

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Khaled Essa

PhD candidate

Name
K.T.S.E.M. Essa MSc
Telephone
+31 71 527 2727
E-mail
k.t.s.e.m.essa@lacdr.leidenuniv.nl

My passion for science began when I was in high school. So, I pursued this passion by following the bachelor of pharmaceutical sciences at Utrecht University in 2015. During the bachelor, I narrowed down my scientific interests to medicinal chemistry and pharmacology. Thus, my first bachelor internship was at the pharmacology department at Utrecht University where I investigated the pathophysiological pathways in cystinosis. During my erasmus master of innovative medicine I switched my focus to medicinal chemistry. My first master internship was performed at the department of drug design in the group of Professor Alexander domling where I synthesized proteolysis targeting chimeras for various targets involved in cancer. I also performed a medicinal chemistry internship at Bayer AG in Germany where I got acquainted with medicinal chemistry research in industry. I performed my master thesis at the drug discovery and safety department (DDS) at the LACDR where I focused on the synthesis of novel modulators of CCR2. After obtaining my master’s degree in 2020, I was employed by the DDS as a supervisor for the master students where I supervised five during their nine months internship in the medicinal chemistry lab. Afterards I decided to continue my research career by starting a PhD at the DDS department under the supervision of Professor Laura Heitman and dr. Daan van der Es. During my PhD I will be focusing on the design, synthesis and evaluation of novel chemical modalities for targeting chemokine receptors (CCRs). Such novel modalities will unravel new insights into successffuly drugging the chemokine receptors as well as expand our current knowledge on their complex binding kinetics. During my PhD I will also be involved in supervising Master and bachelor students during their research projects as well as participate in the supervision of medicinal chemistry lab courses within the bachelor and master programs at the LACDR.

PhD candidate

  • Science
  • Leiden Academic Centre for Drug Research
  • LACDR/Medicinal Chemistry

Work address

Gorlaeus Building
Einsteinweg 55
2333 CC Leiden

Contact

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