Universiteit Leiden

nl en

Edo de Kloet

Professor / guest

Name
Prof.dr. E.R. de Kloet
Telephone
+31 71 527 2727
E-mail
e.kloet@lacdr.leidenuniv.nl

Hormones are crucial for health and disease. In our research we focus on the action of hormones released after stress. These stress hormones program in early life brain circuits that underly emotion and cognition, they protect the brain and regulate the ageing process. Stress hormones determine vulnerability and resilience to depression and schizophrenia depending on genetic predisposition, and are of importance for the onset and progression of neurodegenerative processes. To understand how this enormous diversity in action of stress hormones occurs a unique integrated experimental approach from gene to behaviour is used.

The title of his inaugural lecture was 'Evenwicht in een veranderende wereld'.

De Kloet ER, Joëls M, Holsboer F (2005)  Stress and the brain: from adaptation to disease. Nature Rev Neurosci. 6: 463-475. 

Professor / guest

  • Wiskunde en Natuurwetenschappen
  • Leiden Academic Centre for Drug Research
  • LACDR/Algemeen
  • Galbally, M.; Rossum, E.F.C. van; Watson, S.J.; Kloet, E.R. de & Lewis, A.J. (2019), Trans-generational stress regulation: Mother-infant cortisol and maternal mental health across the perinatal period, Psychoneuroendocrinology 109.'refereed' artikel in een tijdschrift
  • Kumsta, R.; Kliegel, D.; Linden, M.; DeRijk, R. & Kloet, E.R. de (2019), Genetic variation of the mineralocorticoid receptor gene (MR, NR3C2) is associated with a conceptual endophenotype of "CRF-hypoactivity", Psychoneuroendocrinology 105: 79-85.'refereed' artikel in een tijdschrift
  • Molendijk, M.L. & Kloet, E.R. de (2019), Coping with the forced swim stressor: Current state-of-the-art, Behavioural Brain Research 364: 1-10.'non-refereed' artikel in een tijdschrift
  • Brocca, M.E.; Pietranera, L.; Kloet, E.R. de & Nicola, A.F. de (2019), Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy, Cellular and Molecular Neurobiology 39(4): 483-492.'non-refereed' artikel in een tijdschrift
  • Dalm, S.; Karssen, A.M.; Meijer, O.C.; Belanoff, J.K. & Kloet, E.R. de (2019), Resetting the Stress System with a Mifepristone Challenge, Cellular and Molecular Neurobiology 39(4): 503-522.'non-refereed' artikel in een tijdschrift
  • Kloet, E.R. de; Kloet, S.F. de; Kloet, C.S. de & Kloet, A.D. de (2019), Top-down and bottom-up control of stress-coping, Journal of Neuroendocrinology 31(3).'non-refereed' artikel in een tijdschrift
  • Meyer, M.; Lara, A.; Hunt, H.; Belanoff, J.; Kloet, E.R. de; Deniselle, M.C.G. & Nicola, A.F. de (2018), The Selective Glucocorticoid Receptor Modulator Cort 113176 Reduces Neurodegeneration and Neuroinflammation in Wobbler Mice Spinal Cord, Neuroscience 384: 384-396.'refereed' artikel in een tijdschrift
  • Borges-Aguiar, A.C.; Schauffer, L.Z.; Kloet, E.R. de & Schenberg, L.C. (2018), Daily maternal separations during stress hyporesponsive period decrease the thresholds of panic-like behaviors to electrical stimulation of the dorsal periaqueductal gray of the adult rat, Behavioural Brain Research 344: 132-144.'refereed' artikel in een tijdschrift
  • Kloet, E.R. de; Meijer, O.C.; Nicola, A.F. de; Rijk, R.H. de & Joels, M. (2018), Importance of the brain corticosteroid receptor balance in metaplasticity, cognitive performance and neuro-inflammation, Frontiers in Neuroendocrinology 49: 124-145.'non-refereed' artikel in een tijdschrift
  • Galbally, M.; Ryan, J.; IJzendoorn, M. van; Watson, S.J.; Spigset, O.; Lappas, M.; Saffery, R.; Kloet, R. de & Lewis, A.J. (2018), Maternal depression, antidepressant use and placental oxytocin receptor DNA methylation: Findings from the MPEWS study, Psychoneuroendocrinology 90: 1-8.'refereed' artikel in een tijdschrift
  • Hamstra, D.A.; Kloet, E.R. de; Rover, M. de & Does, W. van der (2017), Oral contraceptives positively affect mood in healthy PMS-free women: A longitudinal study, Journal of Psychosomatic Research 103: 119-126.'refereed' artikel in een tijdschrift
  • Kloet, E.R. de & Joels, M. (2017), Brain mineralocorticoid receptor function in control of salt balance and stress-adaptation, Physiology and Behavior 178: 13-20.'refereed' artikel in een tijdschrift
  • Brocca, M.E.; Pietranera, L.; Meyer, M.; Lima, A.; Roig, P.; Kloet, E.R. de & Nicola, A.F. de (2017), Mineralocorticoid receptor associates with pro-inflammatory bias in the hippocampus of spontaneously hypertensive rats, Journal of Neuroendocrinology 29(7).'refereed' artikel in een tijdschrift
  • Joels, M. & Kloet, E.R. de (2017), The brain mineralocorticoid receptor: a saga in three episodes, Journal of Endocrinology 234(1): T49-T66.'refereed' artikel in een tijdschrift
  • Weert, L.T.C.M. van; Buurstede, J.C.; Mahfouz, A.; Braakhuis, P.S.M.; Polman, J.A.E.; Sips, H.C.M.; Roozendaal, B.; Balog, J.; Kloet, E.R. de; Datson, N.A. & Meijer, O.C. (2017), NeuroD Factors Discriminate Mineralocorticoid From Glucocorticoid Receptor DNA Binding in the Male Rat Brain, Endocrinology 158(5): 1511-1522.'refereed' artikel in een tijdschrift
  • Meijer, O.C. & Kloet, E.R. de (2017), A Refill for the Brain Mineralocorticoid Receptor: The Benefit of Cortisol Add-On to Dexamethasone Therapy, Endocrinology 158(3): 448-454.'refereed' artikel in een tijdschrift
  • Hamstra, D.A.; Kloet, E.R. de; Quataert, I.; Jansen, M. & Does, W. van der (2017), Mineralocorticoid receptor haplotype, estradiol, progesterone and emotional information processing, Psychoneuroendocrinology 76: 162-173.'refereed' artikel in een tijdschrift
  • Oster, H.; Challet, E.; Ott, V.; Arvat, E.; Kloet, E.R. de; Dijk, D.J.; Lightman, S.; Vgontzas, A. & Cauter, E. van (2017), The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids, Endocrine Reviews 38(1): 3-45.'refereed' artikel in een tijdschrift
  • Hamstra D., De Kloet E., Quataert I., Jansen M. & Van der Does A.J.W. (2017), Mineralocorticoid receptor haplotype, estradiol, progesterone and emotional information processing., Psychoneuroendocrinology 76: 162–173.article in journal: refereed
  • Hamstra D., Kloet E. de, Rover M. de & Does A.J.W. van der (2017), Oral contraceptives positively affect mood in healthy PMS-free women: A longitudinal study, Journal of Psychosomatic Research 103: 119-126.article in journal: refereed
  • Kloet, E.R. de & Molendijk, M.L. (2016), Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism, Neural Plasticity.'refereed' artikel in een tijdschrift
  • Zalachoras, I.; Verhoeve, S.L.; Toonen, L.J.; Weert, L.T.C.M. van; Vlodrop, A.M. van; Mol, I.M.; Meelis, W.; Kloet, E.R. de & Meijer, O.C. (2016), Isoform switching of steroid receptor co-activator-1 attenuates glucocorticoid-induced anxiogenic amygdala CRH expression, Molecular Psychiatry 21(12): 1733-1739.'refereed' artikel in een tijdschrift
  • Hamstra, D.A.; Kloet, E.R. de; Tollenaar, M.; Verkuil, B.; Manai, M.; Putman, P. & Does, W. van der (2016), Mineralocorticoid receptor haplotype moderates the effects of oral contraceptives and menstrual cycle on emotional information processing, Journal of Psychopharmacology 30(10): 1054-1061.'refereed' artikel in een tijdschrift
  • Kloet, E.R. de; Otte, C.; Kumsta, R.; Kok, L.; Hillegers, M.H.J.; Hasselmann, H.; Kliegel, D. & Joels, M. (2016), Stress and Depression: a Crucial Role of the Mineralocorticoid Receptor, Journal of Neuroendocrinology 28(8).'refereed' artikel in een tijdschrift
  • Molendijk, M.L. & Kloet, E.R. de (2015), Immobility in the forced swim test is adaptive and does not reflect depression, Psychoneuroendocrinology 62: 389-391.'refereed' artikel in een tijdschrift
  • Kumsta, R.; Kliegel, D.; Kloet, E.R. de; Rijk, R.H. de; Linden, M. & Hellhammer, D.H. (2015), Evidence for an association between mineralocorticoid receptor gene haplotypes and psychobiological measures of atypical depression, Psychoneuroendocrinology 61: 14-14.'refereed' artikel in een tijdschrift
  • Daskalakis, N.P.; Kloet, E.R. de; Yehuda, R.; Malaspina, D. & Kranz, T.M. (2015), Early Life Stress Effects on Glucocorticoid-BDNF Interplay in the Hippocampus, Frontiers in Molecular Neuroscience 8.'refereed' artikel in een tijdschrift
  • Polyakova M., Schroeter M.L., Elzinga B.M., Holiga S., Schoenknecht P., De Kloet E.R. & Molendijk M.L. (2015), Brain-derived neurotrophic factor and antidepressive effect of electroconvulsive therapy: Systematic review and meta-analyses of the preclinical and clinical literature, PLoS ONE 3(10): e0141564.article in journal: refereed
  • Polyakova, M.; Schroeter, M.L.; Elzinga, B.M.; Holiga, S.; Schoenknecht, P.; Kloet, E.R. de & Molendijk, M.L. (2015), Brain-Derived Neurotrophic Factor and Antidepressive Effect of Electroconvulsive Therapy: Systematic Review and Meta-Analyses of the Preclinical and Clinical Literature.'refereed' artikel in een tijdschrift
  • Hamstra D.A., De Kloet E.R., Tollenaar M., Verkuil B., Manai M., Putman P. & Van der Does W. (2015), Mineralocorticoid receptor haplotype moderates the influence of female hormones and oral contraceptives on cognition. In: Biological Psychiatry, vol. 77, 9 Supplement. Biological Psychiatry.conference paper: refereed
  • Hamstra, D.A.; Kloet, E.R. de; Tollenaar, M.; Verkuil, B.; Manai, M.; Putman, P. & Does, W. van der (2015), Mineralocorticoid Receptor Haplotype Moderates the Influence of Female Hormones and Oral Contraceptives on Cognition, Biological Psychiatry 77(9).'refereed' artikel in een tijdschrift
  • Hamstra, D.A.; Kloet, E.R. de; Hemert, A.M. van; Rijk, R.H. de & Does, A.J.W. van der (2015), MINERALOCORTICOID RECEPTOR HAPLOTYPE, ORAL CONTRACEPTIVES AND EMOTIONAL INFORMATION PROCESSING, Neuroscience 286: 412-422.'refereed' artikel in een tijdschrift
  • Molendijk M.L. & De Kloet E.R. (2015), Immobility in the forced swim test is adaptive and does not reflect depression, Psychoneuroendocrinology 62: 389-391.article in journal: refereed
  • Hamstra D.A., De Kloet E.R., Van Hemert A.M., De Rijk R.H. & Van der Does A.J.W. (2015), Mineralocorticoid receptor haplotype, oral contraceptives and emotional information processing, Neuroscience 286: 412-422.article in journal: refereed
  • Judd, L.L.; Schettler, P.J.; Brown, E.S.; Wolkowitz, O.M.; Sternberg, E.M.; Bender, B.G.; Bulloch, K.; Cidlowski, J.A.; Kloet, E.R. de; Fardet, L.; Joels, M.; Leung, D.Y.M.; McEwen, B.S.; Roozendaal, B.; Rossum, E.F.C. van; Ahn, J.; Brown, D.W.; Plitt, A. & Singh, G. (2014), Adverse Consequences of Glucocorticoid Medication: Psychological, Cognitive, and Behavioral Effects, American Journal of Psychiatry 171(10): 1045-1051.'refereed' artikel in een tijdschrift
  • Meyer, M.; Deniselle, M.C.G.; Hunt, H.; Kloet, E.R. de & Nicola, A.F. de (2014), The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice, Journal of Steroid Biochemistry and Molecular Biology 143: 40-48.'refereed' artikel in een tijdschrift
  • Kloet, E.R. de (2014), From Receptor Balance to Rational Glucocorticoid Therapy, Endocrinology 155(8): 2754-2769.'refereed' artikel in een tijdschrift
  • Souza, R.R.; Bo, S. dal; Kloet, E.R. de; Oitzl, M.S. & Carobrez, A.P. (2014), Paradoxical mineralocorticoid receptor-mediated effect in fear memory encoding and expression of rats submitted to an olfactory fear conditioning task, Neuropharmacology 79: 201-211.'refereed' artikel in een tijdschrift
  • Groeneweg, F.L.; Royen, M.E. van; Fenz, S.; Keizer, V.I.P.; Geverts, B.; Prins, J.; Kloet, E.R. de; Houtsmuller, A.B.; Schmidt, T.S. & Schaaf, M.J.M. (2014), Quantitation of Glucocorticoid Receptor DNA-Binding Dynamics by Single-Molecule Microscopy and FRAP, PLoS ONE 9(3).'refereed' artikel in een tijdschrift
  • Horst, J.P. ter; Mark, M. van der; Kentrop, J.; Arp, M.; Veen, R. van der; Kloet, E.R. de & Oitzl, M.S. (2014), Deletion of the forebrain mineralocorticoid receptor impairs social discrimination and decision-making in male, but not in female mice, Frontiers in Behavioral Neuroscience 8.'refereed' artikel in een tijdschrift
  • Daskalakis, N.P.; Diamantopoulou, A.; Claessens, S.E.F.; Remmers, E.; Tjalve, M.; Oitzl, M.S.; Champagne, D.L. & Kloet, E.R. de (2014), Early experience of a novel-environment in isolation primes a fearful phenotype characterized by persistent amygdala activation, Psychoneuroendocrinology 39: 39-57.'refereed' artikel in een tijdschrift
  • Schumann, G.; Binder, E.B.; Holte, A.; Kloet, E.R. de; Oedegaard, K.J.; Robbins, T.W.; Walker-Tilley, T.R.; Bitter, I.; Brown, V.J.; Buitelaar, J.; Ciccocioppo, R.; Cools, R.; Escera, C.; Fleischhacker, W.; Flor, H.; Frith, C.D.; Heinz, A.; Johnsen, E.; Kirschbaum, C.; Klingberg, T.; Lesch, K.P.; Lewis, S.; Maier, W.; Mann, K.; Martinot, J.L.; Meyer-Lindenberg, A.; Muller, C.P.; Muller, W.E.; Nutt, D.J.; Persico, A.; Perugi, G.; Pessiglione, M.; Preuss, U.W.; Roiser, J.P.; Rossini, P.M.; Rybakowski, J.K.; Sandi, C.; Stephan, K.E.; Undurraga, J.; Vieta, E.; Wee, N. van der; Wykes, T.; Haro, J.M. & Wittchen, H.U. (2014), Stratified medicine for mental disorders, European Neuropsychopharmacology 24(1): 5-50.'refereed' artikel in een tijdschrift
  • Groeneweg F.L., Royen M.E. van, Fenz F.S., Keizer V.I.P., Geverts B., Prins J., Kloet E.R. de, Houtsmuller A.B., Schmidt T. & Schaaf M.J.M. (2014), Quantitation of Glucocorticoid Receptor DNA-Binding Dynamics by Single-Molecule Microscopy and FRAP, PLoS ONE 9(3): 90532.article in journal: refereed
  • Kloet, E.R. de (2013), Lifetime achievement from a brain-adrenal perspective: On the CRF-urocortin-glucocorticoid balance, Journal of Chemical Neuroanatomy 54: 42-49.'refereed' artikel in een tijdschrift
  • Kloet, E.R. de (2013), Functional profile of the binary brain corticosteroid receptor system: Mediating, multitasking, coordinating, integrating, European Journal of Pharmacology 719(1-3): 53-62.'refereed' artikel in een tijdschrift
  • Datson, N.A.; Oever, J.M.E. van den; Korobko, O.B.; Magarinos, A.M.; Kloet, E.R. de & McEwen, B.S. (2013), Previous History of Chronic Stress Changes the Transcriptional Response to Glucocorticoid Challenge in the Dentate Gyrus Region of the Male Rat Hippocampus, Endocrinology 154(9): 3261-3272.'refereed' artikel in een tijdschrift
  • Harris, A.P.; Holmes, M.C.; Kloet, E.R. de; Chapman, K.E. & Seckl, J.R. (2013), Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour, Psychoneuroendocrinology 38(5): 648-658.'refereed' artikel in een tijdschrift
  • Zalachoras, I.; Houtman, R.; Atucha, E.; Devos, R.; Tijssen, A.M.I.; Hu, P.; Lockey, P.M.; Datson, N.A.; Belanoff, J.K.; Lucassen, P.J.; Joels, M.; Kloet, E.R. de; Roozendaal, B.; Hunt, H. & Meijer, O.C. (2013), Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator, Proceedings of the National Academy of Sciences 110(19): 7910-7915.'refereed' artikel in een tijdschrift
  • Klok M.D., Giltay E.J., Does A.J.W. van der, Geleijnse J.M., Antypa N., Penninx B.W.J.H., Geus E.J.C. de, Willemsen F., Boomsma D.I., Leeuwen N. van, Zitman F.G., Kloet E.R. de & Rijk R.H. de (2011), A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females, Translational Psychiatry 1: e62.article in journal: refereed
  • Kloet E.R. de (5 March 2010), Tussenbalans (Lecture). Leiden.other
  • Kloet E.R. de (5 March 2010), Tussenbalans (Lecture). Leiden.other
  • Oitzl M.S., Champagne D.L., Veen R. van der & Kloet E.R. de (2010), Brain development under stress: hypotheses of glucocorticoid actions revisited, NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 34(6): 853-866.article in journal: refereed
  • Brittijn S.A., Duivesteijn S.J., Belmamoune M., Bertens L.M.F., Bitter W., de Bruijn J. D., Champagne D. L., Cuppen E., Flik G., Van den Broucke-Grauls C. M., Janssen R., de Jong I. E. M., De Kloet E. R., Kros A., Meijer A., Metz J. R., van der Sar A. M., Schaaf M. J., Schulte-Merker S., Spaink H. P., Tak P. P., Verbeek F.J., Vervoordeldonk M.J., Vonk F., Witte F., Yuan H. & Richardson M.K. (2009), Zebrafish development and regeneration: new tools for biomedical research, International Journal of Developmental Biology 53(5-6): 835-850.article in journal: refereed
  • Sarabdjitsingh R.A., Meijer O.C., Schaaf M.J.M. & Kloet E.R. de (2009), Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus., Brain Res. 1249: 43-53.article in journal: refereed
  • Enthoven L, Oitzl MS, Koning N, van der Mark M & de Kloet ER (2008), Hypothalamic-Pituitary-Adrenal Axis Activity of Newborn Mice Rapidly Desensitizes to Repeated Maternal Absence but Becomes Highly Responsive to Novelty, Endocrinology 149(12).'refereed' artikel in een tijdschrift
  • van der Laan S, Sarabdjitsingh RA, Van Batenburg MF, Lachize SB, Li HL, Dijkmans TF, Vreugdenhil E, de Kloet ER & Meijer OC (2008), Chromatin immunoprecipitation scanning identifies glucocorticoid receptor binding regions in the proximal promoter of a ubiquitously expressed glucocorticoid target gene in brain, Journal of Neurochemistry 106(6).'refereed' artikel in een tijdschrift
  • Revsin Y, Van Wijk D, Saravia FE, Oitzl MS, De Nicola AF & De Kloet ER (2008), Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice, Endocrinology 149(7).'refereed' artikel in een tijdschrift
  • de Kloet ER (2008), About stress hormones and resilience to psychopathology, Journal of Neuroendocrinology 20(6).'non-refereed' artikel in een tijdschrift
  • Dijkmans TF, van Hooijdonk LWA, Schouten TG, Kamphorst JT, Vellinga ACA, Meerman JHN, Fitzsimons CP, de Kloet ER & Vreugdenhil E (2008), Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation, Journal of Neurochemistry 105(6).'refereed' artikel in een tijdschrift
  • Enthoven L, de Kloet ER & Oitzl MS (2008), Differential development of stress system (re)activity at weaning dependent on time of disruption of maternal care, Brain Research 1217.'refereed' artikel in een tijdschrift
  • Champagne DL, Bagot RC, van Hasselt F, Ramakers G, Meaney MJ, de Kloet ER, Joels M & Krugers H (2008), Maternal care and hippocampal plasticity: Evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress, Journal of Neuroscience 28(23).'refereed' artikel in een tijdschrift
  • de Kloet ER, Karst H & Joels M (2008), Corticosteroid hormones in the central stress response: Quick-and-slow, Frontiers in Neuroendocrinology 29(2).'non-refereed' artikel in een tijdschrift
  • Olijslagers JE, de Kloet ER, Elgersma Y, van Woerden GM, Joels M & Karst H (2008), Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors, European Journal of Neuroscience 27(10).'refereed' artikel in een tijdschrift
  • Dalm S, Brinks V, van der Mark MH, de Kloet ER & Oitzl MS (2008), Non-invasive stress-free application of glucocorticoid ligands in mice, Journal of Neuroscience Methods 170(1).'refereed' artikel in een tijdschrift
  • De Jong IEM, Steenbergen PJ & De Kloet ER (2008), Strain differences in the effects of adrenalectomy on the mibrain dopamine system: Implication for behavioral sensitization to cocaine, Neuroscience 153(3).'refereed' artikel in een tijdschrift
  • de Kloet ER, de Jong IEM & Oitzi MS (2008), Neuropharmacology of glucocorticoids: Focus on emotion, cognition and cocaine, European Journal of Pharmacology 585(2-3).'non-refereed' artikel in een tijdschrift
  • de Kloet ER, Han F & Meijer OC (2008), From the stalk to down under about brain glucocorticoid receptors, stress and development, Neurochemical Research 33(4).'refereed' artikel in een tijdschrift
  • Datson NA, Morsink MC, Meijer OC & de Kloet ER (2008), Central corticosteroid actions: Search for gene targets, European Journal of Pharmacology 583(2-3).'non-refereed' artikel in een tijdschrift
  • DeRijk RH & de Kloet ER (2008), Corticosteroid receptor polymorphisms: Determinants of vulnerability and resilience, European Journal of Pharmacology 583(2-3).'non-refereed' artikel in een tijdschrift
  • van der Veen R, Abrous DN, de Kloet ER, Piazza PV & Koehl M (2008), Impact of intra- and interstrain cross-fostering on mouse maternal care, Genes, Brain and Behavior 7(2).'refereed' artikel in een tijdschrift
  • van der Laan S, Lachize SB, Vreugdenhil E, De Kloet ER & Meijer OC (2008), Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene, Endocrinology 149(2).'refereed' artikel in een tijdschrift
  • Fitzsimons CP, Ahmed S, Wittevrongel CFW, Schouten TG, Dijkmans TF, Scheenen WJJM, Schaaf MJM, De Kloet ER & Vreugdenhil E (2008), The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells, Molecular Endocrinology -Baltimore- 22(2).'refereed' artikel in een tijdschrift
  • Enthoven L, de Kloet ER & Oitzl MS (2008), Effects of maternal deprivation of CD1 mice on performance in the water maze and swim stress, Behavioural Brain Research 187(1).'refereed' artikel in een tijdschrift
  • Joels M, Karst H, DeRijk R & de Kloet ER (2008), The coming out of the brain mineralocorticoid receptor, Trends in Neurosciences 31(1).'non-refereed' artikel in een tijdschrift
  • Kloet E.R. de (2008), About Stress Hormones and Resilience to Psychopathology, Journal of Neuroendocrinology 20(6): 885-892.article in journal: refereed
  • Revsin Y., Wijk D. van, Saravia F., Oitzl M.S., Nicola A.F. de & Kloet E.R. de (2008), Adrenal hypersensitivity precedes chronic hypercorticism in Streptozotocin-induced diabetes mice, Endocrinology 149(7): 3531-3539.article in journal: refereed
  • Kloet E.R. de, Datson N.A., Revsin Y., Champagne D. & Oitzl M.S. (2008), Brain Corticosteroid Receptor Function in Response to Psychosocial Stressors. In: D.W.Pfaff, C. Kordon, P. Chanson, & Y. Christen (Eds.) Hormones and Social Behaviour. New York; Paris; Tokyo: Springer. 131-150.book chapter
  • Kloet E.R. de, Datson N.A., Revsin Y., Champagne D. & Oitzl M.S. (2008), Brain Corticosteroid Receptor Function in Response to Psychosocial Stressors. In: D.W.Pfaff, C. Kordon, P. Chanson, & Y. Christen (Eds.) Hormones and Social Behaviour. New York; Paris; Tokyo: Springer. 131-150.book chapter
  • Datson N.A., Morsink M.C., Meijer O.C. & Kloet E.R. de (2008), Central corticosteroid actions: Search for gene targets, European Journal of Pharmacology 583(2-3): 272-289.article in journal: refereed
  • Kloet E.R. de (2008), Commentary: neuroendocrine basis, Progress in Brain Research 167: 53-62.article in journal: refereed
  • Meijer O.C. & Kloet E.R. de (2008), Coregulators in CNS Function and Disease. In: R.Kumar & B. W. O'Malley (Ed.) Receptor Coregulators and Human Diseases.: World Scientific Publishing.book chapter
  • Kloet E.R. de, Karst H. & Joels M. (2008), Corticosteroid hormones in the central stress response: quick-and-slow, Frontiers in Neuroendocrinology 29(2): 268-272.article in journal: refereed
  • Rijk R.H. de & Kloet E.R. de (2008), Corticosteroid receptor polymorphisms: determinants of vulnerability and resilience, European Journal of Pharmacology 583(2-3): 303-311.article in journal: refereed
  • Berry A., Greco A., Giorgio M., Pelicci P.G., Kloet E.R. de, Alleva E. & et al .... (2008), Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice, Experimental Gerontology 43(3): 200-208.article in journal: refereed
  • Enthoven L., Kloet E.R. de & Oitzl M.S. (2008), Differential development of stress system (re)activity at weaning dependent on time of disruption of maternal care, Brain Research 1217: 62-69.article in journal: refereed
  • Enthoven L., Kloet E.R. de & Oitzl M.S. (2008), Effects of maternal deprivation of CD1 mice on performance in the water maze and swim stress, The Behavioral and Brain Sciences 187: 195-199.article in journal: refereed
  • Kloet E.R. de & Sarabdjitsingh R.A. (2008), Everything has rhythm: focus on glucocorticoid pulsatility, Endocrinology 149(7): 3241-3243.article in journal: refereed
  • Kloet E.R. de, Han F. & Meijer O.C. (2008), From the stalk to down under about brain glucocorticoid receptors, stress and development, Neurochemical Research 33(4): 637-642.article in journal: refereed
  • Revsin Y., Rekers N.V., Louwe M., Saravia F., Nicola A.F. de, Kloet E.R. de & et al .... (2008), Glucocorticoid Receptor Blockade Normalizes Hippocampal Alterations and Cognitive Impairment in Streptozotocin-Induced Type 1 Diabetes Mice, Neuropsychopharmacology 10(1038): 136.article in journal: refereed
  • Enthoven L., Oitzl M.S., Koning N. de, Mark M. van der & Kloet E.R. de (2008), HPA axis activity of newborn mice rapidly desensitizes to repeated maternal absence, but becomes highly responsive to novelty, Endocrinology 149(12): 6366-6377.article in journal: refereed
  • Veen R. van der, Abrous D.N., Kloet E.R. de, Piazza P.V. & Koehl M. (2008), Impact of intra- and interstrain cross-fostering on mouse maternal care, Genes Brain and Behavior 7(2): 184-192.article in journal: refereed
  • Champagne D., Bagot R.C., Hasselt F. van, Ramakers G., Meaney M.J., Kloet E.R. de & et al .... (2008), Maternal care and hippocampal plasticity: evidence for experience-dependent structural plasticity, altered synaptic functioning, and differential responsiveness to glucocorticoids and stress, Journal of Neuroscience 28(23): 6037-6045.article in journal: refereed
  • Veen R. van der, Koehl M., Abrous D.N., Kloet E.R. de, Piazza P.V. & Roche-Gamonet V. (2008), Maternal environment influences cocaine intake in adulthood in a genotype-dependent manner, PLoS ONE 3(5): 2245.article in journal: refereed
  • Kloet E.R. de, Jong I.E.M. de & Oitzl M.S. (2008), Neuropharmacology of glucocorticoids: Focus on emotion, cognition and cocaine, European Journal of Pharmacology 585(2-3): 473-482.article in journal: refereed
  • Dalm S., Brinks V., Mark M. van der, Kloet E.R. de & Oitzl M.S. (2008), Non-invasive stress-free application of glucocorticoid ligands in mice, Journal of Neuroscience Methods 170(1): 77-84.article in journal: refereed
  • Laan S. van der, Lachize S.B., Vreugdenhil E., Kloet E.R. de & Meijer O.C. (2008), Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene, Endocrinology 149(2): 725-732.article in journal: refereed
  • Olijslagers J.E., Kloet E.R. de, Elgersma Y., Woerden G.M. van, Joels M. & Karst H. (2008), Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors, European Journal of Neuroscience 27(10): 2542-2550.article in journal: refereed
  • Jong I.E.M. de, Steenbergen P.J. & Kloet E.R. de (2008), Strain differences in the effects of adrenalectomy on the midbrain dopamine system: Implication for behavioral sensitization to cocaine, Neuroscience 153(3): 594-604.article in journal: refereed
  • Brinks V., Kloet E.R. de & Oitzl M.S. (2008), Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice, Progress in Brain Research 167: 257-261.article in journal: refereed
  • Kloet E.R. de, Oitzl M.S. & Vermetten E. (2008), Stress hormones and post traumatic stress disorder basic studies and clinical perspectives Amsterdam: Elsevier.book
  • Kloet E.R. de, Oitzl M.S. & Vermetten E. (2008), Stress hormones and post traumatic stress disorder basic studies and clinical perspectives. Amsterdam: Elsevier.book
  • Sarabdjitsingh R.A., Meijer O.C., Schaaf M. & Kloet E.R. de (2008), Subregion-specific differences in translocation patterns of mineralocorticoid and glucocorticoid receptors in rat hippocampus, Brain Research .article in journal: refereed
  • Joels M., Karst H., Rijk R.H. de & Kloet E.R. de (2008), The coming out of the brain mineralocorticoid receptor, Trends in Neurosciences 31(1): 1-7.article in journal: refereed
  • Fitzsimons C.P., Ahmed S., Wittevrongel C., Schouten T.G., Dijkmans T.F., Scheenen W.J., Schaaf M.J.M., Kloet E.R. de & Vreugdenhil E. (2008), The microtubule associated protein Doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells, Molecular Endocrinology 22: 248-262.article in journal: refereed
  • de Kloet ER (2008), Commentary: neuroendocrine basis, Progress in Brain Research 167.'non-refereed' artikel in een tijdschrift
  • Brinks V, de Kloet ER & Oitzl MS (2008), Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice, Progress in Brain Research 167.'non-refereed' artikel in een tijdschrift
  • Schenk GJ, Engels B, Zhang YP, Fitzsimons CP, Schouten T, Kruidering M, de Kloet ER & Vreugdenhil E (2007), A potential role for calcium/calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence, European Journal of Neuroscience 26(12).'refereed' artikel in een tijdschrift
  • Oomen CA, Mayer JL, de Kloet ER, Joels M & Lucassen PJ (2007), Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress, European Journal of Neuroscience 26(12).'refereed' artikel in een tijdschrift
  • Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER & Lightman SL (2007), Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone, Endocrinology 148(11).'refereed' artikel in een tijdschrift
  • Schmidt MV, Oitzl M, Steenbergen P, Lachize S, Wurst W, Muller MB, de Kloet ER & Meijer OC (2007), Ontogeny of steroid receptor coactivators in thehippocampus and their role in regulating postnatal HPA axis function, Brain Research 1174.'refereed' artikel in een tijdschrift
  • Veenema AH, de Kloet ER, de Wilde MC, Roelofs AJ, Kawata M, Buwalda B, Neumann ID, Koolhaas JM & Lucassen PJ (2007), Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice, Journal of Neuroendocrinology 19(7).'refereed' artikel in een tijdschrift
  • Schoonman GG, Evers DJ, Ballieux BE, de Geus EJ, de Kloet ER, Terwindt GM, van Dijk JG & Ferrari MD (2007), Is stress a trigger factor for migraine?, Psychoneuroendocrinology 32(5).'refereed' artikel in een tijdschrift
  • Datson NA, Morsink MC, Atanasova S, Armstrong VW, Zischler H, Schlumbohm C, Dutilh BE, Huynen MA, Waegele B, Ruepp A, de Kloet ER & Fuchs E (2007), Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate, BMC Genomics 8.'refereed' artikel in een tijdschrift
  • Morsink MC, Van Gemert NG, Steenbergen PJ, Joels M, De Kloet ER & Datson NA (2007), Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes, Brain Research 1150.'refereed' artikel in een tijdschrift
  • Han F, Ozawa H, Matsuda KI, Lu H, De Kloet ER & Kawata M (2007), Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy, Journal of Neuroendocrinology 19(4).'refereed' artikel in een tijdschrift
  • Berry A, Capone F, Giorgio M, Pelicci PG, de Kloet ER, Alleva E, Minghetti L & Cirulli F (2007), Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice, Experimental Gerontology 42(1-2).'refereed' artikel in een tijdschrift
  • de Jong IEM, Oitzl MS & de Kloet ER (2007), Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner.'refereed' artikel in een tijdschrift
  • Sibug RM, Datson N, Tijssen AMI, Morsink M, de Koning J, de Kloet ER & Helmerhorst FM (2007), Effects of urinary and recombinant gonadotrophins on gene expression profiles during the murine peri-implantation period, Human Reproduction 22(1).'refereed' artikel in een tijdschrift
  • Jong I.E.M. de, Oitzl M.S. & Kloet E.R. de (2007), Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner, Behavioural Brain Research 177: 329-339.article in journal: refereed
  • Han F., Ozawa H., Matsuda K.I., Lu H., Kloet E.R. de & Kawata M. (2007), Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy, Journal of Neuroendocrinology 19: 229-238.article in journal: refereed
  • Kloet E.R. de (2007), Commentary: Neuroendocribe basis, Progress in Brain Research 167: 53-62.article in journal: refereed
  • Meijer O.C., Kloet E.R. de & McEwen B.S. (2007), Corticosteroid Receptors. In: Fink, G. (Eds.) Encyclopedia of Stress, 2nd edition.: Elsevier Inc., Academic Press. 594-605.book chapter
  • Berry A., Capone F., Giorgio M., Pelicci P.G., Kloet E.R. de, Alleva E., Minghetti L. & Cirulli F. (2007), Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice, Experimental Gerontology 42: 37-45.article in journal: refereed
  • Datson N.A., Morsink M.C., Atanasova A., Armstrong V.W., Zischler H., Schlumbohm C., Dutilh B.E., Huynen M.A., Waegele B., Ruepp A., Kloet E.R. de & Fuchs E. (2007), Development of the first marmoset-specific DNA microarray (EUMAMA): a new genetic tool for large-scale expression profiling in a non-human primate, BMC Genomics 25: 190.article in journal: refereed
  • Veenema A.H., Kloet E.R. de, Wilde M.C. de, Roelofs A.J., Kawata M., Buwalda B., Neumann I.D., Koolhaas J.M. & Lucassen P.J. (2007), Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice, Journal of Neuroendocrinology 19: 489-498.article in journal: refereed
  • Sibug R., Datson N.A., Tijsssen A.M., Morsink M.C., Koning J. de, Kloet E.R. de & Helmerhorst F.M. (2007), Effects of urinary and recombinant gonadotrophins on gene expression profiles during the murine peri-implantation period, Human Reproduction 22(1): 75-82.article in journal: refereed
  • Schoonman G.G., Evers D.J., Ballieux BE, Geus E.J. de, Kloet E.R. de, Terwindt G.M., Dijk J.G. van & Ferrari M.D. (2007), Is stress a trigger factor for migraine?, Psychoneuroendocrinology 32(5): 532-538.article in journal: refereed
  • Schoonman G.G., Evers D.J., Ballieux B.E.P.B., Geus E.J. de, Kloet E.R. de & Terwindt G.M. (2007), Is stress a trigger factor for migraine?, Psychoneuroendocrinology 32(5): 532-538.article in journal: refereed
  • Rijk R.H. de & Kloet E.R. de (2007), Mineralocorticoid Receptor Polymorphisms. In: George F (Ed.) Encyclopedia of Stress.: Academic Press. 744-748.book chapter
  • Schmidt M., Oitzl M.S., Steenbergen P.J., Lachize S.B., Wurst W., Müller M.B., Kloet E.R. de & Meijer O.C. (2007), Ontogeny of steroid receptor co-activators in the hippocampus and their role in regulating postnatal HPA axis function, Brain Research 12: 1-6.article in journal: refereed
  • Kloet E.R. de, Oitzl M.S. & Vermetten E. (2007), Preface, Progress in Brain Research 167: ix-xi.article in journal: refereed
  • Conway-Campbell B.L., McKenna M.A., Wiles C.C., Atkinson H.C., Kloet E.R. de & Lightman S.L. (2007), Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone, Endocrinology 148: 5470-5477.article in journal: refereed
  • Morsink M.C., Gemert N.G., Steenbergen P.J., Joëls M., Kloet E.R. de & Datson N.A. (2007), Rapid glucocorticoid effects on the expression of hippocampal neurotransmission-related genes, Brain Research 30: 14-20.article in journal: refereed
  • Helmerhorst F.M., Siburg R.M. & Kloet E.R. de (2007), Stress Effect of Assisted Reproduction. In: Fink, G. (Eds.) Encyclopedia of Stress.: Elsevier Inc./Academic Press. 596-598.book chapter
  • Kloet E.R. de (2007), Stress Hormones and Post Traumatic Stress Disorders. In: E.R. de Kloet, M.S. Oitzl, E. Vermetten (Eds.) Basic Studies and Clinical Perspectives.: Elsvier B.V.book chapter
  • Kloet E.R. de (2007), Stress System Balance Hypothesis. In: Fink. G. (Ed.) Encyclopedia of Stress.: Elsevier Inc./Academic Press. 646-650.book chapter
  • Joels M., Karst H., Rijk R.H. de & Kloet E.R. de (2007), The coming out of the brain mineralocorticoid, Trends in Neurosciences .article in journal: refereed
  • Kloet E.R. de, Rijk R.H. de & Meijer O.C. (2007), Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?, Nature Clinical Practice Endocrinology & Metabolism 3: 168-179.article in journal: refereed
  • DeRijk RH, Wust S, Meijer OC, Zennaro MC, Federenko IS, Hellhammer DH, Giacchetti G, Vreugdenhil E, Zitman FG & de Kloet ER (2006), A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness, Journal of Clinical Endocrinology and Metabolism 91(12).'refereed' artikel in een tijdschrift
  • Schmidt MV, Levine S, Alam S, Harbich D, Sterlemann V, Ganea K, de Kloet ER, Holsboer F & Muller MB (2006), Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse, Journal of Neuroendocrinology 18(11).'refereed' artikel in een tijdschrift
  • Morsink MC, Joels M, Sarabdjitsingh RA, Meijer OC, De Kloet ER & Datson NA (2006), The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells, Journal of Neurochemistry 99(4).'refereed' artikel in een tijdschrift
  • Schmidt MV, Deussing JM, Oitzl MS, Ohl F, Levine S, Wurst W, Holsboer F, Muller MB & de Kloet ER (2006), Differential disinhibition of the neonatal hypothalamic-pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice, European Journal of Neuroscience 24(8).'refereed' artikel in een tijdschrift
  • Mayer JL, Klumpers L, Maslam S, de Kloet ER, Joels M & Lucassen PJ (2006), Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis, Journal of Neuroendocrinology 18(8).'refereed' artikel in een tijdschrift
  • Saravia FE, Beauquis J, Revsin Y, Homo-Delarche F, de Kloet ER & De Nicola AF (2006), Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment, Cellular and Molecular Neurobiology 26(4-6).'refereed' artikel in een tijdschrift
  • Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B & Seckl JR (2006), Do corticosteroids damage the brain?, Journal of Neuroendocrinology 18(6).'refereed' artikel in een tijdschrift
  • Feldker DEM, Morsink MC, Veenema AH, Datson NA, Proutski V, Lathouwers D, de Kloet ER & Vreugdenhil E (2006), The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates, Brain Research 1089.'refereed' artikel in een tijdschrift
  • Morsink MC, Steenbergen PJ, Vos JB, Karst H, Joels M, Kloet ER & Datson NA (2006), Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time, Journal of Neuroendocrinology 18(4).'refereed' artikel in een tijdschrift
  • de Kloet ER (2006), From punch to profile, Neurochemical Research 31(2).'refereed' artikel in een tijdschrift
  • Rijk R.H. de, Wüst S., Meijer O.C., Zennaro M.C., Federenko I.S., Hellhammer D.H., Giacchetti G., Vreugdenhil E., Zitman F.G. & Kloet E.R. de (2006), A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness, The Journal of Clinical Endocrinology & Metabolism 91: 5083-5089.article in journal: refereed
  • Morsink M.C., Steenbergen P.J., Vos J.B., Karst H., Joëls M., Kloet E.R. de & Datson N.A. (2006), Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time, Journal of Neuroendocrinology 18: 239-252.article in journal: refereed
  • Mayer J.L., Klumpers L., Maslam S., Kloet E.R. de, Joëls M. & Lucassen P.J. (2006), Brief treatment with the glucocorticoid receptor antagonist Mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis, Journal of Neuroendocrinology 18: 629-631.article in journal: refereed
  • Kloet E.R. de & Oitzl M.S. (2006), Cortisol and PTSD: animal experiments and clinical perspectives. In: PTSD Brain Mechanisms and Clinical Implications. Tokyo: Springer Verlag. 13-27.book chapter
  • Schmidt M.V., Deussing J.M., Oitzl M.S., Ohl F., Levine S., Wurst W., Holsboer F., Müller M.B. & Kloet E.R. de (2006), Differential disinhibition of the neonatal hypothalamic-pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice, European Journal of Neuroscience 24: 2291-2298.article in journal: refereed
  • Herbert J.M., Goodyer I.M., Grossman A.B., Hastings M.H., Kloet E.R. de, Lightman S.L., Lupien S.J., Roozendaal B. & Seckl J.R. (2006), Do corticosteroids damage the brain?, Journal of Neuroendocrinology 18: 393-411.article in journal: refereed
  • Kloet E.R. de (2006), From Punch to Profile, Neurochemical Research 31: 131-135.article in journal: refereed
  • Saravia F., Beauquis J., Revsin Y., Homo-Delarche F., Kloet E.R. de & Nicola A.F. de (2006), Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment, Cellular and Molecular Neurobiology 26: 941-955.article in journal: refereed
  • Schmidt M.V., Levine S., Alam S., Harbich D., Sterlemann V., Ganea K., Kloet E.R. de, Holsboer F. & Müller M.B. (2006), Metabolic signals modulate hypothalamic-pituitary-adrenal axis activation during maternal separation of the neonatal mouse, Journal of Neuroendocrinology 18: 865-874.article in journal: refereed
  • Meijer O.C., Laan S. van der, Lachize S.B., Steenbergen P.J. & Kloet E.R. de (2006), Steroid receptor coregulator diversity: what can it mean for the stressed brain?, Neuroscience 138: 891-899.article in journal: refereed
  • Lucassen P.J., Heine V.M., Muller M.B., Beek E.M. van der, Wiegant V.M., Kloet E.R. de, Fuchs E., Swaab D.F. & Czeh B. (2006), Stress, depression and hippocampal apoptosis, CNS and Neurological Disorders - Drug Targets 5: 531-546.article in journal: refereed
  • Morsink M.C., Joëls M., Sarabdjitsingh R.A., Meijer O.C., Kloet E.R. de & Datson N.A. (2006), The dynamic pattern of glucocorticoid receptor-mediated transcriptional responses in neuronal PC12 cells, Journal of Neurochemistry 99: 1282-1298.article in journal: refereed
  • Feldker D.E.M., Morsink M.C., Veenema A.H., Datson N.A., Proutski V., Lathouwers D., Kloet E.R. de & Vreugdenhil E. (2006), The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates, Brain Research 1089: 10-20.article in journal: refereed
  • Meijer OC, van der Laan S, Lachize S, Steenbergen PJ & de Kloet ER (2006), Steroid receptor coregulator diversity: What can it mean for the stressed brain?, Neuroscience 138(3).'refereed' artikel in een tijdschrift
  • Karssen AM, Meijer OC, Berry A, Pinol RS & de Kloet ER (2005), Low doses of dexamethasone can produce a hypocorticosteroid state in the brain, Endocrinology 146(12).'refereed' artikel in een tijdschrift
  • van der Laan S, Lachize SB, Schouten TG, Vreugdenhil E, de Kloet ER & Meijer OC (2005), Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain, Brain Research 1059(2).'refereed' artikel in een tijdschrift
  • Veenema AH, Sijtsma B, Koolhaas JM & De Kloet ER (2005), The stress response to sensory contact in mice: genotype effect of the stimulus animal, Psychoneuroendocrinology 30(6).'refereed' artikel in een tijdschrift
  • de Kloet ER, Joels M & Holsboer F (2005), Stress and the brain: From adaptation to disease, Nature Reviews Neuroscience 6(6).'non-refereed' artikel in een tijdschrift
  • de Kloet ER, Sibug RM, Helmerhorst FM & Schmidt M (2005), Stress, genes and the mechanism of programming the brain for later life, Neuroscience and Biobehavioral Reviews 29(2).'refereed' artikel in een tijdschrift
  • Schmidt M, Levine S, Oitzl MS, van der Mark M, Muller MB, Holsboer F & de Kloet ER (2005), Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse, Endocrinology 146(3).'refereed' artikel in een tijdschrift
  • Meijer OC, Kalkhoven E, van der Laan S, Steenbergen PJ, Houtman SH, Dijkmans TF, Pearce D & de Kloet ER (2005), Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling, Endocrinology 146(3).'refereed' artikel in een tijdschrift
  • Sibug RM, de Koning J, Tijssen AMI, de Ruiter MC, de Kloet ER & Helmerhorst FM (2005), Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF(120) and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period, Human Reproduction 20(3).'refereed' artikel in een tijdschrift
  • Revsin Y, Saravia F, Roig P, Lima A, de Kloet ER, Homo-Delarche F & De Nicola AF (2005), Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes, Brain Research 1038(1).'refereed' artikel in een tijdschrift
  • Dalm S., Enthoven L., Mark M. van der, Karssen A.M., Meijer O.C., Kloet E.R. de & Oitzl M.S. (2005), Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice., Neuroendocrinology 81: 372-380.article in journal: refereed
  • Rijk R.H. de & Kloet E.R. de (2005), Corticosteroid Receptor Genetic Polymorphism and Stress Responsivity, Endocrine 28.article in journal: refereed
  • Rijk R.H. de & Kloet E.R. de (2005), Corticosteroid receptor genetic polymorphisms and stress responsivity., Endocrine 28(3): 263-270.article in journal: refereed
  • Kloet E.R. de, Schmidt M. & Meijer O.C. (2005), Corticosteroid receptors and HPA-axis regulation.. In: Steckler T., Kalin N.H., Reul J.M.H.M. (Eds.) Handbook of Stress and the Brain. Amsterdam: Elsevier. 265-294.book chapter
  • Karssen A.M., Meijer O.C. & Kloet E.R. de (2005), Corticosteroids and the blood-brain barrier.. In: Steckler T., Kalin N.H., Reul J.M.H.M. (Eds.) Handbook of Stress and the Brain. Amsterdam: Elsevier. 329-340.book chapter
  • Kruk M.R. & Kloet E.R. de (2005), Genen, glucocorticoïden en geweld.. In: Blokland A.A.J., Bijleveld C.C.J.H., Donker A.G., Thienpont K. (Eds.) Tijdschrift voor Criminologie - Biosociale perspectieven in de criminologie.. Tijdschrift voor Criminologie: Boom Juridische Uitgevers. 136-141.book chapter
  • Schmidt M., Levine S., Oitzl M.S., Mark M. van der, Müller M.B., Holsboer F. & Kloet E.R. de (2005), Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse., Endocrinology 146: 1458-1464.article in journal: refereed
  • Karssen A.M., Meijer O.C., Berry A., Sanjuan Piñol R. & Kloet E.R. de (2005), Low doses of dexamethasone can produce a hypocorticosteroid state in the brain., Endocrinology 146(12): 5587-5595.article in journal: refereed
  • Laan S. van der, Lachize S.B., Schouten T.G., Vreugdenhil E., Kloet E.R. de & Meijer O.C. (2005), Neuroanatomical distribution and colocalisation of nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid receptors (SMRT) in rat brain., Brain Research 1059: 113-121.article in journal: refereed
  • Revsin Y., Saravia F., Roig P., Lima A., Kloet E.R. de, Homo-Delarche F. & DeNicola A.F. (2005), Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes., Brain Research 1038: 22-31.article in journal: refereed
  • Rijk R.H. de & Kloet E.R. de (2005), Nutrition, Stress and Medical Disorders. Totowa: The Human Pres Inc..book
  • Meijer O.C., Kalkhoven E., Laan S. van der, Steenbergen P.J., Houtman S.H., Dijkmans T.F., Pearce D. & Kloet E.R. de (2005), Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signaling, Endocrinology 146: 1438-1448.article in journal
  • Meijer O.C., Kalkhoven E., Laan S. van der, Steenbergen P.J., Houtman S.H., Dijkmans T.F., Pearce D. & Kloet E.R. de (2005), Steroid receptor coactivator-1 splice variants differentially affect corticosteroid receptor signalling., Endocrinology 146: 1438-1448.article in journal: refereed
  • Kloet E.R. de, Joëls M. & Holsboer F. (2005), Stress and the Brain: from adaptation to disease., Nature Reviews/Neuroscience 6: 463-475.article in journal: refereed
  • Kloet E.R. de, Sibug R., Helmerhorst F.M. & Schmidt M. (2005), Stress, genes and the mechanism of programming the brain for later life., Behavioral Neuroscience 29: 271-81.article in journal: refereed
  • Kloet E.R. de, Sibug R.M., Helmerhorst F.M. & Schmidt M. (2005), Stress, genes and the mechanism of programming the brain for later life., NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 29: 271-281.article in journal: refereed
  • Kloet E.R. de, Siburg R.M., Helmerhorst F.M. & Schmidt M. (2005), Stress, genes and the mechanism of programming the brain for later life, NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 29: 271-281.article in journal
  • Rijk R.H. de & Kloet E.R. de (2005), Stress, glucocorticoids, and the brain.. In: Yehuda S., Mostofsky D.I. (Eds.) Nutrients, Stress, and Medical Disorders.. Totowa, NJ, USA: Humana Press. 111-135.book chapter
  • Veenema A.H., Sijtsma B., Koolhaas J.M. & Kloet E.R. de (2005), The stress response to sensory contact in mice: genotype effect of the stimulus animal., Psychoneuroendocrinology 30: 550-557.article in journal: refereed
  • Sibug R., Koning de J, Ruiter de M.C., Kloet E.R. de & Helmerhorst F.M. (2005), Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period., Human Reproduction 20: 649-656.article in journal: refereed
  • Sibug R.M., Koning J. de, Tijssen A.M.I., Ruiter M.C. de, Kloet E.R. de & Helmerhorst F.M. (2005), Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period., Human Reproduction 20: 649-656.article in journal: refereed
  • Sibug R.M., Koning J. de, Tijssen A.M.I., Ruiter M.C. de, Kloet E.R. de & Helmerhorst F.M. (2005), Urinary gonadotropins but not recombinant gonadotropins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period, Human Reproduction 20: 649-656.article in journal: refereed
  • Dalm S, Enthoven L, Meijer OC, van der Mark MH, Karssen AM, de Kloet ER & Oitzl MS (2005), Age-related changes in hypothalamic-pituitary-adrenal axis activity of male C57BL/6J mice, Neuroendocrinology 81(6).'refereed' artikel in een tijdschrift
  • Datson NA, Meijer L, Steenbergen PJ, Morsink MC, van der Laan S, Meijer OC & de Kloet ER (2004), Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression, European Journal of Neuroscience 20(10).'refereed' artikel in een tijdschrift
  • Enthoven L, Dalm S, de Kloet ER & Oitzl MS (2004), Swim posture of mice does not affect performance in the water maze, Brain Research 1003(1-2).'refereed' artikel in een tijdschrift
  • Schmidt M, Enthoven L, van Woezik JHG, Levine S, de Kloet ER & Oitzl MS (2004), The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation, Journal of Neuroendocrinology 16(1).'refereed' artikel in een tijdschrift
  • Grootendorst J, Enthoven L, Dalm S, de Kloet ER & Oitzl MS (2004), Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice, Behavioural Brain Research 148(1-2).'refereed' artikel in een tijdschrift
  • Veenema A.H., Koolhaas J.M. & Kloet E.R. de (2004), Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines., Annals of the New York Academy of Sciences 1018: 255-265.article in journal: refereed
  • Datson N.A., Meijer L., Steenbergen P.J., Morsink M.C., Laan S. van der, Meijer O.C. & Kloet E.R. de (2004), Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression, European Journal of Neuroscience 20: 2541-2554.article in journal: refereed
  • Datson N.A., Meijer L., Steenbergen P.J., Morsink M.C., Laan S. van der, Meijer O.C. & Kloet E.R. de (2004), Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregions-specific differences in expression., European Journal of Neuroscience 20: 2541-2554.article in journal: refereed
  • Jong I.E.M. & Kloet E.R. de (2004), Glucocorticoids and vulnerability to psychostimulant drugs: toward substrate and mechanism, Annals of the New York Academy of Sciences 1018: 192-198.article in journal: refereed
  • Fauser B.C.J.M., Kloet E.R. de, Lips P., Michels R.P.J., Wiersinga W.M., Sitsen J.M.A. & Wimersma Greidanus Tj.B. van (2004), Hormonen. In: Sitsen J.M.A., Smits J.F.M., Smits P., Cohen A.F., Bortel L.M. van (Eds.) Farmacologie. Maarssen: Elsevier gezondheidszorg. 195-224.book chapter
  • Kloet E.R. de (2004), Hormones and the stressed brain, Annals of the New York Academy of Sciences 1018: 1-15.article in journal: refereed
  • Grootendorst J., Enthoven L., Dalm S., Kloet E.R. de & Oitzl M.S. (2004), Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice., Behavioural Brain Research 148: 167-177.article in journal: refereed
  • Kloet E.R. de (2004), In Honour of David de Wied - Obituary, Psychoneuroendocrinology 29: 823-824.article in magazine/newspaper
  • Karssen A.M., Meijer O.C., Pons D. & Kloet E.R. de (2004), Localization of mRNA expression of p-glycoprotein ar the blood-brain barrier and in the hippocampus., Annals of the New York Academy of Sciences 1032: 308-311.article in journal: refereed
  • Karssen A.M., Meijer O.C., Pons D. & Kloet E.R. de (2004), Localization of mRNA expression of p-glycoprotein at the blood-brain barrier and in the hippocampus., Annals of the New York Academy of Sciences 1032: 308-311.article in journal: refereed
  • Mulder M.T., Jansen P.J., Janssen B.J.A., Berg W.D.J. van de, Boom H., Havekes L.M., Kloet E.R. de, Ramaekers F.C.S. & Blokland A (2004), Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus., Neurobiology of Disease 16: 212-219.article in journal: refereed
  • Rijk R.H. de, Zitman F.G. & Kloet E.R. de (2004), Neuro-endocrinologie van de stress respons, hoofdstuk 3. In: Hovens H, Timmermans L, Loonen AJ (Eds.) Handboek neurobiologische psychiatrie. Utrecht: De Tijdstroom. 65-85.book chapter
  • Rijk R.H. de, Zitman F.G. & Kloet E.R. de (2004), Neurologie van de stress respons.. In: Hovens J.E., Timmermans L., Loonen A.J.M. (Eds.) Handboek neurobiologische psychiatrie. Utrecht: De Tijdstroom. 65-85.book chapter
  • Beek E.M. van der, Wiegant V.M., Schouten W.G., Eerdenburg F.J., Loijens L.W., Plas C. van der, Benning M.A., Vries H. de, Kloet E.R. de & Lucassen P.J. (2004), Neuronal number, volume, and apoptosis of the left dentate gyrus of chronically stressed pigs correlate negatively with basal saliva cortisol levels, Hippocampus 14: 688-700.article in journal: refereed
  • Kloet E.R. de & Rijk R.H. de (2004), Signaling pathways in brain involved in predisposition and pathogenesis of stress-related disease. Genetic and kinetic factors affecting the MR/GR balance., Annals of the New York Academy of Sciences 1032: 14-34.article in journal: refereed
  • Kloet E.R. de & Rijk R.H. de (2004), Signaling pathways in brain involved in predisposition and pathogenesis of stress-related disease. Genetic and kinetic factors affecting the MR/GR balance., Annals of the New York Academy of Sciences 1032: 14-34.article in journal: refereed
  • Kloet E.R. de & Rijk R.H. de (2004), Signaling Pathways in Brain Involved in Predisposition and Pathogenesis of Stress-Related Disease. Genetic and Kinetic Factors Affecting the MR/GR Balance., Annals of the New York Academy of Sciences (1032): 14-34.article in journal: refereed
  • Praag H.M. van, Kloet E.R. de & Os J. van (2004), Stress, the Brain and Depression. Cambridge: Cambridge University Press.book
  • Enthoven L., Dalm S., Kloet E.R. de & Oitzl M.S. (2004), Swim posture of mice does not affect performance in the water maze, Brain Research 1003: 36-41.article in journal: refereed
  • Schmidt M., Enthoven L., Woezik J.H.G. van, Levine S., Kloet E.R. de & Oitzl M.S. (2004), The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation., Journal of Neuroendocrinology 16: 52-57.article in journal: refereed
  • Veenema AH, Koolhaas JM & De Kloet ER (2004), Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines, Annals of the New York Academy of Sciences 1018.'refereed' artikel in een tijdschrift
  • De Jong IEM & De Kloet ER (2004), Glucocorticoids and vulnerability to psychostimulant drugs: Toward substrate and mechanism, Annals of the New York Academy of Sciences 1018.'refereed' artikel in een tijdschrift
  • De Kloet ER (2004), Hormones and the stressed brain, Annals of the New York Academy of Sciences 1018.'refereed' artikel in een tijdschrift
  • Karssen AM, Meijer OC, Pons D & De Kloet ER (2004), Localization of mRNA expression of P-glycoprotein at the blood-brain barrier and in the hippocampus, Annals of the New York Academy of Sciences 1032.'refereed' artikel in een tijdschrift
  • De Kloet ER & Derijk R (2004), Signaling pathways in brain involved in predisposition and pathogenesis of stress-related disease - Genetic and kinetic factors affecting the MR/GR balance, Annals of the New York Academy of Sciences 1032.'refereed' artikel in een tijdschrift
  • Feldker DEM, Datson NA, Veenema AH, Proutski V, Lathouwers D, de Kloet ER & Vreugdenhil E (2003), GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: Technical and biological implications, Journal of Neuroscience Research 74(5).'refereed' artikel in een tijdschrift
  • Feldker DEM, de Kloet ER, Kruk MR & Datson NA (2003), Large-scale gene expression profiling of discrete brain regions: Potential, limitations, and application in genetics of aggressive behavior, Behavior Genetics 33(5).'refereed' artikel in een tijdschrift
  • DeRijk RH, Schaaf M, Stam FJ, de Jong IEM, Swaab DF, Ravid R, Vreugdenhil E, Cidlowski JA, de Kloet ER & Lucassen PJ (2003), Very low levels of the glucocorticoid receptor beta isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry, Molecular Brain Research 116(1-2).'refereed' artikel in een tijdschrift
  • Meijer OC, Karssen AM & de Kloet ER (2003), Cell- and tissue-specific effects of corticosteroids in relation to glucocorticoid resistance: examples from the brain, Journal of Endocrinology 178(1).'refereed' artikel in een tijdschrift
  • Schmidt M, Enthoven L, van der Mark M, Levine S, de Kloet ER & Oitzl MS (2003), The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse, International Journal of Developmental Neuroscience 21(3).'refereed' artikel in een tijdschrift
  • Veenema AH, Meijer OC, de Kloet ER & Koolhaas JM (2003), Genetic selection for coping style predicts stressor susceptibility, Journal of Neuroendocrinology 15(3).'refereed' artikel in een tijdschrift
  • Veenema AH, Meijer OC, de Kloet ER, Koolhaas JM & Bohus BG (2003), Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression, Hormones and Behavior 43(1).'refereed' artikel in een tijdschrift
  • Rinne T, de Kloet ER, Wouters L, Goekoop JG, de Rijk RH & van den Brink W (2003), Fluvoxamine reduces responsiveness of HPA axis in adult female BPD patients with a history of sustained childhood abuse, Neuropsychopharmacology 28(1).'refereed' artikel in een tijdschrift
  • Feldker DEM, Datson NA, Veenema AH, Meulmeester E, de Kloet ER & Vreugdenhil E (2003), Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice, European Journal of Neuroscience 17(2).'refereed' artikel in een tijdschrift
  • Veenema A.H., Meijer O.C., Kloet E.R. de, Koolhaas J.M. & Bohus B.G.J. (2003), Differences in basal and stress-induced HPS regulation of wild house mice selected for high and low aggression., Hormones and Behavior 43: 197-204.article in journal: refereed
  • Kloet E.R. de, Oitzl M.S. & et al .... (2003), Discussion to: “Prenatal stress and cognitive development and temperament in infants” by Kan K. Buitelaar et al. and “Who cares for a stressed brain? The mother, the kid or both?” by E. Ronald de Kloet and Melly S. Oitzl, Neurobiology of Aging 24: S67-S68.article in journal: refereed
  • Rinne Th., Kloet E.R. de, Wouters L, Goekoop J.G., Rijk R.H. de & Brink W. van den (2003), Fuvoxamine reduces hyperresponsiveness of HPA-axis in adult female BPD patients with a history of sustained childhood abuse, Neuropsychopharmacology 28: 126-132.article in journal: refereed
  • Feldker D.E.M., Datson N.A., Veenema A.H., Proutski V., Lathouwers D., Kloet E.R. de & Vreugdenhil E. (2003), GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications., Journal of Neuroscience Research 74: 701-716.article in journal: refereed
  • Veenema A.H., Meijer O.C., Kloet E.R. de & Koolhaas J.M. (2003), Genetic selection for coping style predicts stressor susceptibility., Journal of Neuroendocrinology 15: 256-267.article in journal: refereed
  • Kloet E.R. de (2003), Hormones, Brain and Stress, Endocrine Regulations 37: 51-68.article in journal
  • Feldker D.E.M., Kloet E.R. de, Kruk M.R. & Datson N.A. (2003), Large-scale gene expression profiling of discrete brain regions: potential, limitations, and application in genetics of aggressive behavior., Behavior Genetics 33: 537548.article in journal: refereed
  • Meijer O.C., Karssen A.M. & Kloet E.R. de (2003), MECHANISMS OF STEROID ACTION AND RESISTANCE IN INFLAMMATION. Cell- and tissue-specific effects of corticosteroids in relation to glucocorticoid resistance: examples from the brain., Journal of Endocrinology 178: 13-18.article in journal: refereed
  • Kloet E.R. de (2003), Neurosteroiden, Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde 28(4): 179-182.article in journal
  • Kloet E.R. de (2003), Neurosteroïden, Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde 28: 179-182.article in journal: refereed
  • Schmidt M., Oitzl M.S., Muller B., Ohl F., Wurst W., Holsboer F., Levine S. & Kloet E.R. de (2003), Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice., Neuroscience 119: 589-595.article in journal: refereed
  • Feldker D.E.M., Datson N.A., Veenema A.H., Meulmeester E., Kloet E.R. de & Vreugdenhil E. (2003), Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice., European Journal of Neuroscience 17: 379-387.article in journal: refereed
  • Schmidt M., Enthoven L., Mark M. van der, Levine S., Kloet E.R. de & Oitzl M.S. (2003), The postnatal development of the hypothalamic-pituitary-adrenal axis in the mouse., International Journal of Developmetnal Neuroscience 21: 125-132.article in journal: refereed
  • Rijk R.H. de, Schaaf M.J.M., Stam F.J., Jong I.E.M., Swaab D.F., Ravid R., Vreugdenhil E., Cidlowski J.A., Kloet E.R. de & Lucassen P.J. (2003), Very low levels of the glucocorticoid receptor beta isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry., Molecular Brain Research 116: 17-26.article in journal: refereed
  • Rijk R.H. de, Schaaf M.J.M., Stam F.J., Jong I.E.M., Swaab D.F., Ravid R., Vreugdenhil E., Cidlowski J.A., Kloet E.R. de & Lucassen P.J. (2003), Very low levels of the glucocorticoid receptor beta-isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry., Molecular Brain Research 116: 17-26.article in journal: refereed
  • Rijk R.H. de, Schaaf M.J.M., Stam F.J., Jong I.E.M., Swaab D.F., Ravid R., Vreugdenhil E., Kloet E.R. de & Lucassen P.J. (2003), Very low levels of the glucocorticoid receptor B isoform in the human hippocampus as shown by Tagman RT-PCR and immunocytochemistry, Molecular Brain Research 116: 17-26.article in journal: refereed
  • Rijk R.H. de, Schaaf M., Stam F.J., Jong I.E.M. de, Swaab D.F., Ravid R., Vreugdenhil E., Cilowski J.A., Kloet E.R. de & Lucassen P.J. (2003), Very low levels of the glucocorticoid receptor ß-isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry, Molecular Brain Research 116: 17-26.article in journal: refereed
  • Kloet E.R. de & Oitzl M.S. (2003), Who cares for a stressed brain? The mother, the kid or both?, Neurobiology of Aging 24: S61-S65.article in journal: refereed
  • Kloet E.R. de & Oitzl M.S. (2003), Who cares for a stressed brain? Ther mother, the kid, or both?, Neurobiology of Aging 24: S61-S65.article in journal: refereed
  • Schmidt M, Oitzl MS, Muller MB, Ohl F, Wurst W, Holsboer F, Levine S & De Kloet ER (2003), Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice, Neuroscience 119(2).'refereed' artikel in een tijdschrift
  • Van Kampen NA, De Kloet ER, Flugge G & Fuchs E (2002), Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews, European Journal of Pharmacology 457(2-3).'refereed' artikel in een tijdschrift
  • Rinne T, de Kloet ER, Wouters L, Goekoop JG, DeRijk RH & van den Brink W (2002), Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse, Biological Psychiatry 52(11).'refereed' artikel in een tijdschrift
  • de Kloet ER, Grootendorst J, Karssen AA & Oitzl MS (2002), Gene x environment interaction and cognitive performance: Animal studies on the role of corticosterone, Neurobiology of Learning and Memory 78(3).'refereed' artikel in een tijdschrift
  • Sibug RM, Helmerhorst FM, Tijssen AMI, de Kloet ER & de Koning J (2002), Estrogen reduces vascular endothelial growth factor(164) expression in the mouse nucleus paraventricularis of the hypothalamus, Neuroscience Letters 333(3).'refereed' artikel in een tijdschrift
  • Schmidt M, Oitzl MS, Levine S & de Kloet ER (2002), The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation, Developmental Brain Research 139(1).'refereed' artikel in een tijdschrift
  • Karssen AM, Meijer OC, van der Sandt ICJ, De Boer AG, De Lange ECM & De Kloet ER (2002), The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone, Journal of Endocrinology 175(1).'refereed' artikel in een tijdschrift
  • Grootendorst J, Kempes MM, Lucassen PJ, Dalm S, de Kloet ER & Oitzl MS (2002), Differential effect of corticosterone on spatial learning abilities in apolipoprotein E knockout and C57BL/6J mice, Brain Research 953(1-2).'refereed' artikel in een tijdschrift
  • Evans SJ, Datson NA, Kabbaj M, Thompson RC, Vreugdenhil E, De Kloet ER, Watson SJ & Akil H (2002), Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis, European Journal of Neuroscience 16(3).'refereed' artikel in een tijdschrift
  • de Kloet E (2002), Stress in the brain: implications for treatment of depression, Acta Neuropsychiatrica 14(4).'refereed' artikel in een tijdschrift
  • DeRijk RH, Schaaf M & de Kloet ER (2002), Glucocorticoid receptor variants: clinical implications, Journal of Steroid Biochemistry and Molecular Biology 81(2).'non-refereed' artikel in een tijdschrift
  • Sibug RM, Helmerhorst FM, Tijssen AMI, de Kloet ER & de Koning J (2002), Gonadotrophin stimulation reduces VEGF(120) expression in the mouse uterus during the peri-implantation period, Human Reproduction 17(6).'refereed' artikel in een tijdschrift
  • Rahmouni K, Sibug RM, De Kloet ER, Barthelmebs M, Grima M, Imbs JL & De Jong W (2002), Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension, European Journal of Pharmacology 436(3).'refereed' artikel in een tijdschrift
  • van den Buuse M, van Acker SABE, Fluttert MFJ & de Kloet ER (2002), Involvement of corticosterone in cardiovascular responses to an open-field novelty stressor in freely moving rats, Physiology and Behavior 75(1-2).'refereed' artikel in een tijdschrift
  • van Acker SABE, Oitzl MS, Fluttert MFJ & de Kloet ER (2002), Centrally regulated blood pressure response to vasoactive peptides is modulated by corticosterone, Journal of Neuroendocrinology 14(1).'refereed' artikel in een tijdschrift
  • Kampen M. van, Kloet E.R. de, Flügge G & Fuchs E. (2002), Blockade of glucocorticoid receptors with ORG 34116 does not normalize stress-induced symptoms in male tree shrews., European Journal of Pharmacology 457: 207-216.article in journal: refereed
  • Acker S.A.B.E. van, Oitzl M.S., Fluttert M.F.J. & Kloet E.R. de (2002), Centrally regulated blood pressure response to vasoactive peptides is modulated by corticosterone., Journal of Neuroendocrinology 14: 56-63.article in journal: refereed
  • Joels M., Krugers H.J. & Kloet E.R. de (2002), Corticosteroid actions on electrical activity in the brain.. In: Pfaff D.W., Arnold A.P., Etgen A.M., Fahrbach S.E., Rubin R.T. (Eds.) Hormones, Brain and Behavior. San Diego: Academic Press/Elsevier Science. 601-626.book chapter
  • Joëls M., Krugers H.J. & Kloet E.R. de (2002), Corticosteroid actions on electrical activity in the brain. In: Pfaff, D.W., Arnold, A.P., Etgen, A.M., Fahrbach, S.E., Rubin, R.T. (Eds.) Hormones, Brain and Behavior. San Diego, CA, USA: Academic Press/Elsevier-Science. 601-626.book chapter
  • Grootendorst J., Kempes MM, Lucassen P.J., Dalm S., Kloet E.R. de & Oitzl M.S. (2002), Differential effect of corticosterone on spatial learning abilities in apolipoprotein E knockout and C57BL/6J mice., Brain Research 953: 281-285.article in journal: refereed
  • Rahmouni K., Sibug R.M., Kloet E.R. de, Barthelmebs M., Grima M., Imbs J-L & Jong W de (2002), Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension., European Journal of Pharmacology 436: 207-216.article in journal: refereed
  • Sibug R.M., Helmerhorst F.M., Tijssen A.M.I., Kloet E.R. de & Koning J. de (2002), Estrogen reduces vascular endothelial growth factor 164 expression in the mouse nucleaus paraventricularis of the hypothalamus, Neuroscience Letters 333: 199-202.article in journal: refereed
  • Sibug R.M., Helmerhorst F.M., Tijssen A.M.I., Kloet E.R. de & Koning J. de (2002), Estrogen reduces vascular endothelial growth factor164 expression in the mouse nucleus paraventricularis of the hypothalamus., Neuroscience Letters 333: 199-202.article in journal: refereed
  • Evans S.J., Datson N.A., Kabbaj M., Thompson R.C., Vreugdenhil E., Kloet E.R. de, Watson S.J. & Akil H. (2002), Evaluation of Affymetrix Gene Chip sensitivity in rat hippocampal tissue using SAGE analysis., European Journal of Neuroscience 16: 409-413.article in journal: refereed
  • Rinne Th., Kloet E.R. de, Wouters L, Goekoop J.G. & Brink W. van den (2002), Fluvoxamine reduces responsiveness of HPA axis in adult female BPD patients with a history of sustained childhood abuse., Neuropsychopharmacology 28: 126-132.article in journal: refereed
  • Rinne Th., Kloet E.R. de, Wouters L, Goekoop J.G. & Brink W. van den (2002), Fluvoxamine reduces responsiveness of HPA axis in adult female BPD patients with a history of sustained childhood abuse., Neuropsychopharmacology 28: 126-132.article in journal: refereed
  • Kloet E.R. de, Grootendorst J., Karssen A.M. & Oitzl M.S. (2002), Gene X environment interaction and cognitive performance: animal studies on the role of corticosterone, Neurobiology of Learning and Memory 78: 570-577.article in journal: refereed
  • Kloet E.R. de, Grootendorst J., Karssen A.M. & Oitzl M.S. (2002), Gene X environment interaction and cognitive performance: aninal studies on the role of corticosterone., Neurobiology of Learning and Memory 78: 570-577.article in journal: refereed
  • Rijk R.H. de, Schaaf M.J.M. & Kloet E.R. de (2002), Glucocorticoid receptor variants: clinical implications., Journal of Steroid Biochemistry & Molecular Biology 81: 103-122.article in journal: refereed
  • Sibug R.M., Helmerhorst F.M., Tijssen A.M.I., Kloet E.R. de & Koning J. de (2002), Gonadotrophin stimulation reduces VEGF120 expression in the mouse uterus during the peri-implantation period, Human Reproduction 17: 1643-1648.article in journal: refereed
  • Sibug R.M., Helmerhorst F.M., Tijssen A.M.I., Kloet E.R. de & Koning J. de (2002), Gonadotrophin stimulation reduces VEGF120 expression in the mouse uterus during the peri-implantation period., Human Reproduction 17: 1643-1648.article in journal: refereed
  • Lucassen P.J., Muller M.B., Holsboer F., Holtrop A., Wouda J., Hoogendijk W.J., Kloet E.R. de & Swaab D.F. (2002), Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure., American Journal of Pathology 158: 453-468.article in journal: refereed
  • Rinne Th., Kloet E.R. de, Wouters L, Goekoop J.G., Rijk R.H. de & Brink W. van den (2002), Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse., Biological Psychiatry (52): 1102-1112.article in journal: refereed
  • Rinne Th., Kloet E.R. de, Wouters L, Goekoop J.G., Rijk R.H. de & Brink W. van den (2002), Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse., Biological Psychiatry 52: 1102-1112.article in journal: refereed
  • Buuse M. van den, Acker S.A.B.E. van, Fluttert M.F.J. & Kloet E.R. de (2002), Involvement of corticosterone in cardiovascular responses to an open-field novelty stressor in freely moving rats., Physiology and Behavior 75: 207-215.article in journal: refereed
  • Buusse M van den, Acker S.A.B.E. van, Fluttert M.F.J. & Kloet E.R. de (2002), Involvement of corticosterone in cardiovascular responses to an open-fiels novelty stressor in freely moving rats, Physiology and Behavior 75: 207-215.article in journal: refereed
  • Buuse M. van den, Acker S.A.B.E. van, Fluttert M.F.J. & Kloet E.R. de (2002), Involvement of corticosterone in cardiovascular response to an open-field novelty stressor in freely moving rats., Physiology and Behavior 75: 207-215.article in journal: refereed
  • Kloet E.R. de (2002), Stress in the brain: implications for treatment of depression., Acta Neuropsychiatrica 14(4): 155-166.article in journal: refereed
  • Schmidt M., Oitzl M.S., Levine S. & Kloet E.R. de (2002), The HPA system during the postnatal development of CD1 mice and the effects of maternal deprivation., Developmental Brain Research 139: 39-49.article in journal: refereed
  • Karssen A.M., Meijer O.C., Sandt I.C.J. van der, Boer A.G. de, Lange E. de & Kloet E.R. de (2002), The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone., Journal of Endocrinology 175: 251-260.article in journal: refereed
  • Vreugdenhil E, de Kloet ER, Schaaf M & Datson NA (2001), Genetic dissection of corticosterone receptor function in the rat hippocampus, European Neuropsychopharmacology 11(6).'refereed' artikel in een tijdschrift
  • Derijk RH, Schaaf MJM, Turner G, Datson NA, Vreugdenhil E, Cidlowski J, De Kloet ER, Emery P, Sternberg EM & Detera-Wadleigh SD (2001), A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis, Journal of Rheumatology 28(11).'refereed' artikel in een tijdschrift
  • Grootendorst J, Oitzl MS, Dalm S, Enthoven L, Schachner M, de Kloet ER & Sandi C (2001), Stress alleviates reduced expression of cell adhesion molecules (NCAM, L1), and deficits in learning and corticosterone regulation of apolipoprotein E knockout mice, European Journal of Neuroscience 14(9).'refereed' artikel in een tijdschrift
  • Grootendorst J, de Kloet ER, Vossen C, Dalm S & Oitzl MS (2001), Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57B1/6 mice, Behavioural Brain Research 125(1-2).'refereed' artikel in een tijdschrift
  • Van Acker SABE, Fluttert MFJ, Sibug RM & De Kloet ER (2001), Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress, European Journal of Pharmacology 430(1).'refereed' artikel in een tijdschrift
  • Oitzl MS, Reichardt HM, Joels M & de Kloet ER (2001), Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory, Proceedings of the National Academy of Sciences 98(22).'refereed' artikel in een tijdschrift
  • Vreugdenhil E, Engels B, Middelburg R, van Koningsbruggen S, Knol J, Veldhuisen B & de Kloet ER (2001), Multiple transcripts generated by the DCAMKL gene are expressed in the rat hippocampus, Molecular Brain Research 94(1-2).'refereed' artikel in een tijdschrift
  • Schaaf MJM, Workel JO, Lesscher HM, Vreugdenhil E, Oitzl MS & de Kloet ER (2001), Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats, Brain Research 915(2).'refereed' artikel in een tijdschrift
  • Datson NA, van der Perk J, de Kloet ER & Vreugdenhil E (2001), Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression, European Journal of Neuroscience 14(4).'refereed' artikel in een tijdschrift
  • Sibug RM, Oitzl MS, Workel JO & de Kloet ER (2001), Maternal deprivation increases 5-HT1A receptor expression in the CA1 and CA3 areas of senescent Brown Norway rats, Brain Research 912(1).'refereed' artikel in een tijdschrift
  • Mulder M, Blokland A, van den Berg DJ, Schulten H, Bakker AHF, Terwel D, Honig W, de Kloet ER, Havekes LM, Steinbusch HWM & de Lange ECM (2001), Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging, Laboratory Investigation 81(7).'refereed' artikel in een tijdschrift
  • Lucassen PJ, Vollmann-Honsdorf GK, Gleisberg M, Czeh B, De Kloet ER & Fuchs E (2001), Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew, European Journal of Neuroscience 14(1).'refereed' artikel in een tijdschrift
  • Workel JO, Oitzl MS, Fluttert M, Lesscher T, Karssen A & de Kloet ER (2001), Differential and age-dependent effects of maternal deprivation on the hypothalamic-pituitary-adrenal axis of brown Norway rats from youth to senescence, Journal of Neuroendocrinology 13(7).'refereed' artikel in een tijdschrift
  • Karssen AM, Meijer OC, van der Sandt ICJ, Lucassen PJ, de Lange ECM, de Boer AG & de Kloet ER (2001), Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain, Endocrinology 142(6).'refereed' artikel in een tijdschrift
  • van den Buuse M, van Acker SABE, Fluttert M & de Kloet ER (2001), Blood pressure, heart rate, and behavioral responses to psychological "novelty" stress in freely moving rats, Psychophysiology 38(3).'refereed' artikel in een tijdschrift
  • Lucassen PJ, Muller MB, Holsboer F, Bauer J, Holtrop A, Wouda J, Hoogendijk WJG, De Kloet ER & Swaab DF (2001), Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure, American Journal of Pathology 158(2).'non-refereed' artikel in een tijdschrift
  • Rijk R.H. de, Schaaf M.J.M., Turner G, Datson N.A., Vreugdenhil E., Cidlowski J., Kloet E.R. de, Emery P., Sternberg E.M. & Detera-Wadleigh S.D. (2001), A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor betaisoform mRNA is associated with rheumatoid arthritis, Journal of Rheumatology 28: 2383-2388.article in journal: refereed
  • Mulder M., Blokland A, Berg D.J. van den, Schulten H, Bakker A.H.F., Terwel D, Honig W., Kloet E.R. de, Havekes L.M., Steinbusch HWM & Lange E.C.M. de (2001), Apolipoprotein E protect against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging, Laboratory Investigation 81: 953-960.article in journal: refereed
  • Buusse M van den, Acker S.A.B.E. van, Fluttert M.F.J. & Kloet E.R. de (2001), Blood pressure, heart rate, and behavioural responses to psychological "novelty" stress in freely moving rats., Psychophysiology 38: 490-499.article in journal: refereed
  • Rijk R.H. de, Meijer O.C. & Kloet E.R. de (2001), Brain corticosteroid receptors: targets for treatment of depression. In: Thakore J. (Ed.) Physical Consequences of Depression.. 23-52.book chapter
  • Rijk R.H. de, Meijer O.C. & Kloet E.R. de (2001), Brain corticosteroid receptors: targets for treatment of depression.. In: Thakore J. (Ed.) Physical Consequences of Depression.. 23-52.book chapter
  • Lucassen P.J., Vollman-Honsdorf G.K., Gleisberg M., Czéh B., Kloet E.R. de & Fuchs E. (2001), Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew., European Journal of Neuroscience 14: 161-166.article in journal: refereed
  • Schaaf M.J.M., Workel J.O., Lesscher H., Vreugdenhil E., Oitzl M.S. & Kloet E.R. de (2001), Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats., Brain Research 915: 227-233.article in journal: refereed
  • Kloet E.R. de (2001), Corticosteroïden. In: Sitsen J.M.A., Breimer D.D., Cools A.R., Smits P., Smits J.F.M., Wimersma Greidanus Tj.B. van (Eds.) Farmacologie. Maarssen: Elsevier. 194-205.book chapter
  • Workel J.O., Oitzl M.S., Fluttert M.F.J., Lesscher H., Karssen A.M. & Kloet E.R. de (2001), Differential and age-dependent effects on the hypothalamic-pituitary-adrenal axis of Brown Norway rats from youth to senescence., Journal of Neuroendocrinology 13: 569-580.article in journal: refereed
  • Datson N.A., Perk-de Jong J., Kloet E.R. de & Vreugdenhil E. (2001), Expression profile of 30,000 genes in rat hippocampus using SAGE., Hippocampus 11: 430-444.article in journal: refereed
  • Vreugdenhil E., Kloet E.R. de, Schaaf M.J.M. & Datson N.A. (2001), Genetic dissection of corticosterone receptor function in the rat hippocampus, European Neuropsychopharmacology 11(6): 423-430.article in journal: refereed
  • Lucassen P.J., Muller M.B., Holsboer F., Bauer J., Holtrop A., Wouda J., Hoogendijk W.J., Kloet E.R. de & Swaab D.F. (2001), Hoppicampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure., American Journal of Pathology 158: 453-468.article in journal: refereed
  • Datson N.A., Perk J. van der, Kloet E.R. de & Vreugdenhil E. (2001), Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression., European Journal of Neuroscience 14: 675-689.article in journal: refereed
  • Visser J.T.J., Lentjes E.G.W.M., Haspels I, Graffelman W, Blauw B., Kloet E.R. de & Nagelkerken A.M. (2001), Increased sensitivity to glucocorticoids in peripheral blood mononuclear cells of Chronic Fatigue Syndrome patients without evidence for altered density of affinity of glucocorticoid receptors., J Invest Med 49: 195-204.article in journal: refereed
  • Visser Jelle, Lentjes E.G.W.M., Haspels I, Graffelman W, Blauw B., Kloet E.R. de & Nagelkerken L. (2001), Increased sensitivity to glucocorticoids in peripheral blood mononuclear cells of chronic fatigue syndrome patients, without evidence for altered density or affinity of glucocorticoid receptors, Journal of Investigative Medicine (49): 195-204.article in journal: refereed
  • Visser J., Lentjes E.G.W.M., Haspels I, Graffelman A.W., Blauw B., Kloet E.R. de & Nagelkerken L. (2001), Increased sensitivity to glucocorticoids in peripheral blood mononuclear cells of chronic fatigue syndrome patients, without evidence for altered density or affinity of glucocorticoid receptors, Journal of Investigative Medicine 49: 195-204.article in journal: refereed
  • Acker S.A.B.E. van, Fluttert M.F.J., Sibug R.M. & Kloet E.R. de (2001), Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses tp brief restraint stress., European Journal of Pharmacology 430: 87-91.article in journal: refereed
  • Visser J., Graffelman A.W., Blauw B., Haspels I, Lentjes E.G.W.M., Kloet E.R. de & Nagelkerken L. (2001), LPS-induced IL-10 production in whole blood cultures from chronic fatigue syndrome patients is increased but supersensitive to inhibition by dexamethasone, Journal of Neuroimmunology 119: 343-349.article in journal: refereed
  • Visser J., Graffelman W, Blauw B., Haspels I, Lentjes E.G.W.M., Kloet E.R. de & Nagelkerken L. (2001), LPS-induced IL-10 production in whole blood cultures from chronic fatigue syndrome patients is increased but supersensitive to inhibition by dexamethasone, Journal of Neuroimmunology (119): 343-349.article in journal: refereed
  • Sibug R.M., Oitzl M.S., Workel J.O. & Kloet E.R. de (2001), Maternal deprivation increases 5-HT-1A receptor expression in the CA1 and CA3 areas of senescent Brown Norway rats., Brain Research 912: 95-98.article in journal: refereed
  • Karssen A.M., Meijer O.C., Sandt I.C.J. van der, Lucassen P.J., Lange E.C.M. de, Boer A.G. de & Kloet E.R. de (2001), Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain., Endocrinology 142: 2686-2694.article in journal: refereed
  • Vreugdenhil E., Engels B.M., Koningsbruggen S. van, Knol J., Veldhuisen B. & Kloet E.R. de (2001), Multiple transcripts generated by the DCAMKL gene are expressed in the rat hippocampus., Molecular Brain Research 94: 67-74.article in journal: refereed
  • Oitzl M.S., Reichardt H.M., Joëls M. & Kloet E.R. de (2001), Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory., 98: 12790-12795.article in journal: refereed
  • Grootendorst J., Kloet E.R. de, Vossen C., Dalm S. & Oitzl M.S. (2001), Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57B1/6 mice., Behavioural Brain Research 125: 249-259.article in journal: refereed
  • Grootendorst J., Kloet E.R. de, Dalm S. & Oitzl M.S. (2001), Reversal of cognitivve deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience., Neuroscience 108: 237-247.article in journal: refereed
  • Grootendorst J., Oitzl M.S., Dalm S., Enthoven L., Schachner M. & Kloet E.R. de (2001), Stress alleviates reduced expression of cell adhesion molecules (NCAM, L1) and deficits in learning and corticosterone regulation of apolipoprotein E knockout mice., European Journal of Neuroscience 14: 1505-1514.article in journal: refereed
  • Kloet E.R. de (2001), Stress in de Hersenen.. In: Natuurkundige Voordrachten.. 104-110.book chapter
  • Datson NA, van der Perk J, de Kloet ER & Vreugdenhil E (2001), Expression profile of 30,000 genes in rat hippocampus using SAGE, Hippocampus 11(4).'refereed' artikel in een tijdschrift
  • Grootendorst J, De Kloet ER, Dalm S & Oitzl MS (2001), Reversal of cognitive deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience, Neuroscience 108(2).'refereed' artikel in een tijdschrift
  • Karst H, Karten YJG, Reichardt HM, de Kloet ER, Schutz G & Joels M (2000), Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers, Nature Neuroscience 3(10).'refereed' artikel in een tijdschrift
  • Oitzl MS, Workel JO, Fluttert M, Frosch F & de Kloet ER (2000), Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats, European Journal of Neuroscience 12(10).'refereed' artikel in een tijdschrift
  • de Kloet ER (2000), Stress in the brain, European Journal of Pharmacology 405(1-3).'refereed' artikel in een tijdschrift
  • Sibug RM, Compaan JC, Meijer OC, Van der Gugten J, Olivier B & De Kloet ER (2000), Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus, European Journal of Pharmacology 404(1-2).'refereed' artikel in een tijdschrift
  • Meijer OC, Steenbergen PJ & De Kloet ER (2000), Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary.'refereed' artikel in een tijdschrift
  • Grootendorst J, Mulder M, Haasdijk E, de Kloet ER & Jaarsma D (2000), Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion.'refereed' artikel in een tijdschrift
  • de Kloet ER, van Acker SABE, Sibug RM, Oitzl MS, Meijer OC, Rahmouni K & de Jong W (2000), Brain mineralocorticoid receptors and centrally regulated functions.'refereed' artikel in een tijdschrift
  • Dalm S, Grootendorst J, de Kloet ER & Oitzl MS (2000), Quantification of swim patterns in the Morris water maze.'refereed' artikel in een tijdschrift
  • Schaaf MJM, Duurland R, de Kloet ER & Vreugdenhil E (2000), Circadian variation in BDNF mRNA expression in the rat hippocampus.'refereed' artikel in een tijdschrift
  • Visser J.T.J., Kloet E.R. de & Nagelkerken A.M. (2000), Altered glucocorticoid regulation of the immune response in the Chronic Fatigue Syndrome., Annals of the New York Academy of Sciences 917: 868-875.article in journal: refereed
  • Visser J.T.J., Kloet E.R. de & Nagelkerken A.M. (2000), Altered glucocorticoid regulation of the immune response in the Chronic Fatigue Syndrome., Annals of the New York Academy of Sciences 917: 868-875.article in journal: refereed
  • Visser J.T.J., Kloet E.R. de & Nagelkerken L. (2000), Altered glucocortiod regulation of the immune response in the chronic fatigue syndrome, Annals of the New York Academy of Sciences 917(868): 868-875.article in journal: refereed
  • Kloet E.R. de, Acker S.A.B.E. van, Sibug R.M., Oitzl M.S., Meijer O.C., Rahmouni K. & Jong W. de (2000), Brain mineralocorticoid receptors and centrally regulated functions, Kidney International 57: 1329-1336.article in journal: refereed
  • Karst H., Karten Y.J.G., Reichardt H.M., Kloet E.R. de, Schütz G. & Joëls M. (2000), Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers, Nature Neuroscience 3: 977-978.article in journal: refereed
  • Meijer O.C., Kloet E.R. de & McEwen B.S. (2000), Corticosteroid Receptors. In: Fink G. (Ed.) Encyclopedia of Stress..book chapter
  • Schaaf M.J.M., Kloet E.R. de & Vreugdenhil E. (2000), Corticosterone effects on BDNF expression in the hippocampus (Review), Stress 3: 201-208.article in journal: refereed
  • Meijer O.C., Steenbergen P.J. & Kloet E.R. de (2000), Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary, Endocrinology 141: 2192-2199.article in journal: refereed
  • Sibug R.M., Compaan J.C., Meijer O.C., Gugten J. van der, Olivier B. & Kloet E.R. de (2000), Effects on flesinoxan on corticosteroid receptor expression in the rat hippocampus, European Journal of Pharmacology 404: 111-119.article in journal: refereed
  • Kloet E.R. de (2000), Fron Glucose to Glucocorticoids (Lecture). Beerse.other
  • Oitzl M.S., Workel J.O., Fluttert M.F.J., Frösch F. & Kloet E.R. de (2000), Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats, European Journal of Neuroscience 12: 3770-3780.article in journal: refereed
  • Kloet E.R. de (2000), Neuropendocriene aspecten van stress: een preklinische visie (Lecture). Groningen.other
  • Grootendorst J., Mulder M.T., Haasdijk E., Kloet E.R. de & Jaarsma D. (2000), Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion, Brain Research 868: 165-175.article in journal: refereed
  • Dalm S., Grootendorst J., Kloet E.R. de & Oitzl M.S. (2000), Quantification of swim patterns in the Morris water maze, Behavior Research Methods Instruments and Computers 32: 134-139.article in journal: refereed
  • Kloet E.R. de (2000), Stress and serotonin: implications for development of novel anti-depressants (Lecture). Leiderdorp.other
  • Kloet E.R. de (2000), Stress, apolipoprotein E and Alzheimer's Disease (Lecture). Buenos Aires.other
  • Levine S., Dent G. & Kloet E.R. de (2000), Stress-Hyporesponsive Period. In: Fink G. (Ed.) Encyclopedia of Stress..book chapter
  • Kloet E.R. de (2000), Stress in the Brain, European Journal of Pharmacology 405: 1329-1336.article in journal: refereed
  • Kloet E.R. de (2000), Stress in the Brain (Lecture). Hamburg.other
  • Karssen A.M. & Kloet E.R. de (2000), Synthetic Glucocorticoids. In: Fink G. (Ed.) Encyclopedia of Stress..book chapter
  • Haller J., Millar S., Schraaf J. van de, Kloet E.R. de & Kruk M.R. (2000), The active phase-related increase in corticosterone and aggression are linked, Journal of Neuroendocrinology 12: 431-436.article in journal: refereed
  • Cabrera R., Korte S.M., Lentjes E.G.W.M., Romijn F., Schönbaum E, Nicola A.F. de & Kloet E.R. de (2000), The amount of free corticosterone is increased during lipopolysaccharide--induced fever, Life Sciences 66: 553-562.article in journal: refereed
  • Cabrera R., Korte S.M., Lentjes E.G.W.M., Romijn F.P.H.T.M., Schonbaum E., Nicola A.F. de & Kloet E.R. de (2000), The amount of free corticosterone is increased during lipopolysaccharide-induced fever., Life Sciences 66: 553-562.article in journal: refereed
  • Kloet E.R. de, Meijer O.C., Vreugdenhil E. & Joëls M. (2000), The Yin and Yang of Nuclear Receptors: Symposium on Nuclear Receptors in Brain, Endocrinol Metabol II: 245-248.article in journal: refereed
  • Visser JTJ, De Kloet ER & Nagelkerken L (2000), Altered glucocorticoid regulation of the immune response in the chronic fatigue syndrome, Annals of the New York Academy of Sciences 917.'refereed' artikel in een tijdschrift
  • Cabrera R, Korte SM, Lentjes EGWM, Romijn F, Schonbaum E, De Nicola A & De Kloet ER (2000), The amount of free corticosterone is increased during lipopolysaccharide-induced fever.'refereed' artikel in een tijdschrift
  • Schaaf M.J., Sibug R.M., Duurland R., Fluttert M.F., Oitzl M.S., Kloet E.R. de & Vreugdenhil E. (1999), Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training, Stress 3(2): 173-183.article in journal: refereed
  • Vreugdenhil E., Datson N., Engels B., Jong J. de, Koningsbruggen S. van, Schaaf M.J.M. & Kloet E.R. de (1999), Kainate-elicited seizures induce mRNA encoding a CaMK-related peptide: a putative modulator of kinase activity in rat hippocampus, Journal of neurobiology 39(1): 41-50.article in journal: refereed
  • Oitzl M.S., Fluttert M.F.J. & Kloet E.R. de (1998), Acute blockade of hippocampal glucocorticoid receptors facilitates spatial learning in rats, Brain Research Bulletin 797: 159-162.article in journal: refereed
  • Oitzl M.S., Fluttert M.F.J. & Kloet E.R. de (1998), Acute blockade of hippocampal glucocorticoid receptors facilitates spatial learning in rats, Brain Research Bulletin 797: 159-162.article in journal: refereed
  • Meijer O.C., Kortekaas R., Oitzl M.S. & Kloet E.R. de (1998), Acute rise in corticosterone facilitates 5-HT1A receptor-mediated behavioural responses, European Journal of Pharmacology 351: 7-14.article in journal: refereed
  • Meijer O.C., Kortekaas R., Oitzl M.S. & Kloet E.R. de (1998), Acute rise in corticosterone facilitates 5-HT1A receptor-mediated behavioural responses, European Journal of Pharmacology 351: 7-14.article in journal: refereed
  • Kloet E.R. de (1998), Adrenal steroids and cognitive functions and mental well being in the elderly (Lecture). Berlin, Germany.other
  • Kloet E.R. de (1998), Adrenal steroids and cognitive functions and mental well being in the elderly (Lecture). Berlin, Germany.other
  • Kloet E.R. de (1998), Brain corticosteroid receptor balance and homeostatic control: implications for disease (Lecture). Munich, Germany.other
  • Kloet E.R. de (1998), Brain corticosteroid receptor balance and homeostatic control: implications for disease (Lecture). Munich, Germany.other
  • Kloet E.R. de (1998), Brain corticosteroid receptor balance in health and disease (Lecture). Mendoza, Argentina.other
  • Kloet E.R. de, Vreugdenhil E., Oitzl M.S. & Joëls M. (1998), Brain corticosteroid receptor balance in health and disease, Endocrine Reviews 19: 269-301.article in journal: refereed
  • Kloet E.R. de (1998), Brain corticosteroid receptors and depression (Lecture). Glasgow, UK.other
  • Kloet E.R. de (1998), Brain corticosteroid receptors and neural stress circuitry (Lecture). Melbourne, Australia.other
  • Visser J., Blauw B., Hinloopen B., Brommer E.J.P., Kloet E.R. de, Kluft C. & Nagelkerken L. (1998), CD4 T lymphocytes from patients with chronic fatigue syndrome have decreased interferon-... production and increased sensitivity to dexamethasone, The Journal of Infectious Diseases 177: 451-454.article in journal: refereed
  • Oitzl M.S., Fluttert M.F.J., Sutanto W. & Kloet E.R. de (1998), Continuous blockade of brain glucocorticoid receptors facilitated spatial learning and memory in rats, European Journal of Neuroscience 10: 3759-3766.article in journal: refereed
  • Kloet E.R. de (1998), Corticosteroid dysregulation and depression: cause or effect? (Lecture). Trier, Germany.other
  • Vreugdenhil E. & Kloet E.R. de (1998), Corticosteroid hormones and neuronal vulnerability: towards identification of candidate vulnerability genes. In: Leeuwen F.W. van, Salehi A., Giger R.J., Holtmaat A.J.G.D., Verhaagen J. (Eds.) Progress in Brain Research.: Elsevier science BV. 9-22.book chapter
  • Kloet E.R. de, Meijer O.C. & Haarst A.D. van (1998), Corticosteroid hormones and the organization of the stress response system. In: Levy A., Grauer E., Ben-Nathan D., Kloet E.R. (Eds.) New Frontiers in Stress Research; Modulation of Brain Function. Amsterdam: Harwood Academic Publishers. 1-19.book chapter
  • Kloet E.R. de (1998), Corticosteroid modulation of cognitive function (Lecture). Volkswagen Stiftung, Berlin, Germany.other
  • Kloet E.R. de (1998), Corticosteroid receptor imbalance and stress-related disorders: cause or effect? (Lecture). Buenos Aires, Argentina.other
  • Meijer O.C. & Kloet E.R. de (1998), Corticosterone and serotonergic neurotransmission in the hippocampus: functional implications of the central corticosteroid receptor diversity., Critical Reviews in Neurobiology 12: 1-20.article in journal: refereed
  • Visser J., Boxtel-Dezaire A. van, Methorst D., Bunt T., Kloet E.R. de & Nagelkerken L. (1998), Differential regulation of Interleukin-10 (IL-10) and IL-12 by glucocorticoids in vitro, Blood (ASH Annual Meeting Abstracts) - print 91: 4255-4264.article in journal: refereed
  • Schaaf M.J.M., Jong J. de, Kloet E.R. de & Vreugdenhil E. (1998), Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone, Brain Research Bulletin 813: 112-120.article in journal: refereed
  • Oers H.J.J. van, Kloet E.R. de & Levine S. (1998), Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress, Brain Research Bulletin 111: 245-253.article in journal: refereed
  • Sibug R.M., Compaan J.C., Meijer O.C., Gugten J. van der, Olivier B. & Kloet E.R. de (1998), Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels, European Journal of Pharmacology 353: 207-214.article in journal: refereed
  • Kloet E.R. de (1998), Functional implications of brain cortocosteroid receptor diversity (Lecture). Univ. of Umea, Sweden.other
  • Griep E.N., Boersma J.W., Lentjes E.G.W.M., Prins P.A., Korst J.K. van der & Kloet E.R. de (1998), Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain, Journal of Rheumatology 25: 1374-1381.article in journal: refereed
  • Griep E.N., Boersma J.W., Lentjes E.G.W.M., Prins A.P.A., Korst J.K. van der & Kloet E.R. de (1998), Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain., Journal of Rheumatology 25: 1374-1381.article in journal: refereed
  • Gómez F., Kloet E.R. de & Armario A. (1998), Glucocorticoid negative feedback on the HPA axis in five inbred rat strains, American Journal of Physiology 274: R420-R427.article in journal: refereed
  • Kloet E.R. de (1998), Glucocorticoids, stress and aging: effect of early life eperience (Lecture). Utrecht, NL.other
  • Grillo C.A., Saravia F., Ferrini M., Piroli G., Roig P., García S.I., Kloet E.R. de & Nicola A.F. de (1998), Increased expression of Magnocellular vasopressin mRNA ub rats with deoxycorticosterone-acetate induced salt appetite, Neuroendocrinology 68: 105-115.article in journal: refereed
  • Rostène W., Nicot A., Scarcriaux V., Kloet E.R. de, Laprat D.P. & Brod A. (1998), Interaction between glucocorticoids and neurotensin in normal and stress responses. In: Levy A., Grauer E., Ben-Nathan D., Kloet E.R. de (Eds.) New Frontiers in Stress Research: Modulation of Brain Function.. Amsterdam: Harwood Academic Publishers. 83-94.book chapter
  • Oers H.J.J. van, Kloet E.R. de, Whelan T. & Levine S. (1998), Maternal deprivation effect on the infant's neural stress markers is reversed by tactile stimulation and feeding but not by suppressing corticosterone, Journal of Neuroscience 18: 10171-10179.article in journal: refereed
  • Kloet E.R. de (1998), Modulation of brain corticosteroid receptor function (Lecture). Sevilla, Spain.other
  • Kloet E.R. de (1998), Neuroendocrinology of stress: focus on feedback (Lecture). London, UK.other
  • Kloet E.R. de (1998), Neuroendocrinology of stress: implications for neuropharmaceutical intervention (Lecture). Melbourne, Australia.other
  • Rostène W., Nicot A., Scarcériaux V., Kloet E.R. de, Pélaprat D. & Bérod A. (1998), New Frontiers in Stress Research; Modulation of Brain Function. In: Levy A., Grauer E., Ben-Nathan D., Kloet E.R. de (Eds.) Interaction between glucocorticoids and neurotensin in normal and stress responses. Amsterdam, NL: Harwood Academic Publishers. 83-94.book chapter
  • Meijer O.C., Lange E.C.M. de, Boer A.G. de, Workel J.O., Breimer D.D. & Kloet E.R. de (1998), Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice, Endocrinology 139: 1789-1793.article in journal: refereed
  • Mulder M., Ravid R., Swaab D.F., Kloet E.R. de, Haasdijk E.D., Julk J., Boom J. van der & Havekes A.M. (1998), Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4, Alzheimer Disease and Associated Disorders 12: 198-203.article in journal: refereed
  • Nicola A.F. de, Ferrini M., Gonzalez S.L., Gonzalez Deniselle M.C., Grillo C.A., Piroli G., Saravia F. & Kloet E.R. de (1998), Regulation of gene expression by corticoid hormones in the brain and spinal cord, Journal of Steroid Biochemistry and Molecular Biology 65: 253-272.article in journal: refereed
  • Betancur C., Cabrera R., Kloet E.R. de & Rostène W. (1998), Role of endogenous neurotensin in the behavorial and neuroendocrine effects of cocaine, Neuropsychopharmacology 19: 322-332.article in journal: refereed
  • Kloet E.R. de (1998), Steroiden bij stress en veroudering (Lecture). Utrecht, NL.other
  • Oers H.J.J. van, Kloet E.R. de & Levine S. (1998), The ontogeny of glucocorticoid negative feedback: influence of maternal deprivation, Endocrinology 129: 2838-2846.article in journal: refereed
  • Krugers H.J., Mulder M., Korf J., Havekes A.M., Kloet E.R. de & Joels M. (1997), Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice., Neuroreport 8: 2505-2510.article in journal: refereed
  • Krugers H.J., Mulder M., Korf J., Havekes A.M., Kloet E.R. de & Joels M. (1997), Altered synaptic plasticity in ippocampal CA1 area of apoliprotein E deficient mice., Neuroreport 8: 2505-2510.article in journal: refereed
  • Oitzl M.S., Haarst A.D. van & Kloet E.R. de (1997), Behavioral and neuroendocrine responses controlled by the concerted action of central mineralocorticoid (MRs) and glucocorticoid receptors (GRs)., Psychoneuroendocrinology 22: S87-S93.article in journal: refereed
  • Joels M., Karten Y.J.G., Hesen W. & Kloet E.R. de (1997), Corticosteroid effects on electrical properties of brain cells: temporal aspects and role of antoglucocorticoids., Psychoneuroendocrinology 22: S81-S86.article in journal: refereed
  • Schaaf M.J.M., Hoetelmans R.W.M., Kloet E.R. de & Vreugdenhil E. (1997), Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus., Journal of Neuroscience Research 48: 334-341.article in journal: refereed
  • Kloet E.R. de (1997), Early experience, genotype and vulnerability to depressive illness.. In: De pathogenese van stoornissen in de affectregulatie; een psychobiologische integratie.. Leiden (Boerhaave cursus).book chapter
  • Karst H., Bosma A., Hendriksen E., Kamphuis W., Kloet E.R. de & Joels M. (1997), Effect of adrenalectomy in kindled rats., Neuroendocrinology 66: 348-359.article in journal: refereed
  • Meijer O.C., Oosten R.V. van & Kloet E.R. de (1997), Elevated basal trough levels of corticosterone suppress hippocampal 5-hydroxytryptamine-1A receptor expression in adrenally intact rats: implication for the pathogenesis of depression., Neuroscience 80: 419-426.article in journal: refereed
  • Nicot A., Rowe W.B., Kloet E.R. de, Betancur C., Jessop D.S., Lightman S.L., Quirion R., Rostene W. & Bérod A. (1997), Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus., Journal of Neuroendocrinology 9: 263-269.article in journal: refereed
  • Haarst A.D. van, Oitzl M.S. & Kloet E.R. de (1997), Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus., Neurochemical Research 22: 1323-1328.article in journal: refereed
  • Zant J.L., Mooij A., Griep E.N., Boersma J.W. & Kloet E.R. de (1997), Fibromyalgia in relation to the process of early attachment., Nederlands Tijdschrift voor Pijn en Pijnbestrijding 17: 25-27.article in journal
  • Kloet E.R. de, Vreugdenhil E., Oitzl M.S. & Joëls M. (1997), Glucocorticoid feedback resistance., Trends in Endocrinology and Metabolism 8: 26-33.article in journal: refereed
  • Rijk R.H. de, Sternberg E.M. & Kloet E.R. de (1997), Glucocorticoid receptor function in health and disease., Current opinion in Endocrinology and Diabetes 4: 185-193.article in journal: refereed
  • Lentjes E.G.W.M., Griep E.N., Boersma J.W., Romijn F.P.H.T.M. & Kloet E.R. de (1997), Glucocorticoid receptors, fibromyalgia and low back pain., Psychoneuroendocrinology 22: 604-614.article in journal: refereed
  • Lentjes E.G.W.M., Griep E.N., Boersma J.W., Romijn F.P.H.T.M. & Kloet E.R. de (1997), Glucocoticoid receptors, fibromyalgia and low back pain., Psychoneuroendocrinology 22: 603-614.article in journal: refereed
  • Bhatnagar M., Cintra A., Chadi G., Lindberg J., Oitzl M.S., Kloet E.R. de, Möller A., Agnati L.F. & Fuxe K. (1997), Neurochemical changes in the hippocampus of the Brown Norway rat during aging., Neurobiology of Aging 18: 319-327.article in journal: refereed
  • Oers H.J.J. van, Kloet E.R. de & Levine S. (1997), Persistent, but paradoxical, effects on HPA regulation of infants maternally deprived at different ages., Stress 1: 249-261.article in journal: refereed
  • Meijer O.C., Cole T.J., Schmid W., Schütz G., Joels M. & Kloet E.R. de (1997), Regulation of hippocampal 5-HT-1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor., Molecular Brain Research 46: 290-296.article in journal: refereed
  • Oitzl M.S., Mulder M., Lucassen P.J., Havekes A.M., Grootendorst J. & Kloet E.R. de (1997), Severe learning deficits in apolipoprotein E-knockout mice in a water maze task., Brain Research Bulletin 752: 189-196.article in journal: refereed
  • Oitzl M.S., Mulder M.T., Lucassen P.J., Havekes L.M., Grootendorst J. & Kloet E.R. de (1997), Severe learning deficits in apolipoprotein E-knockout mice in a water maze task., Brain Research 752: 189-196.article in journal: refereed
  • Oitzl M.S., Mulder M., Lucassen P.J., Havekes A.M., Grootendorst J. & Kloet E.R. de (1997), Severe learning deficts in apolipoprotein E-knockout mice in a water maze task., Brain Research Bulletin 752: 189-196.article in journal: refereed
  • Ferrini M.G., Grillo C.A., Piroli G., Kloet E.R. de & Nicola A.F. de (1997), Sex difference in glucocorticoid regulation of vasopressin mRNA in the paraventricular hypothalamic nucleus., Cellular and Molecular Neurobiology 17: 671-686.article in journal: refereed
  • Oitzl M.S., Kloet E.R. de, Joels M., Schmid W. & Cole T.J. (1997), Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption., European Journal of Neuroscience 9: 2284-2296.article in journal: refereed
  • Szuran T.F., Haarst A.D. van, Kloet E.R. de & Pliska V. (1997), Steroid receptors in the rat hippocampus: A note to the methodology of their binding assay., Journal of Receptor & Signal Transduction Research 17: 337-354.article in journal: refereed
  • Workel J.O., Oitzl M.S., Ledeboer A. & Kloet E.R. de (1997), The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24 h maternal deprivation at day 3., Developmental Brain Research 103: 199-203.article in journal: refereed
  • Kloet E.R. de (1997), Toekomstperspectieven in de behandeling van de ziekte van Alzheimer., Folia Pharmaceutica 9: 21-31.article in journal
  • Kloet E.R. de (1997), Why dexamethasone poorly penetrates in brain., Stress 2: 13-20.article in journal: refereed

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