Cas van der Horst
Analyst
- Name
- C. van der Horst MSc
- Telephone
- +31 71 527 4607
- c.van.der.horst@lacdr.leidenuniv.nl
Analyst
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Bouma, J., Broekhuis J.D., Horst C. van der, Kumar P., Ligresti A., Stelt M. van der & Heitman L.H. (2023), Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor, Biochemical Pharmacology 218: 115924.
- Li X., Chang H., Bouma J., Paus L.V. de, Mukhopadhyay P., Paloczi J., Mustafa M., Horst C. van der, Kumar S.S., Wu L., Yu Y., Berg R.J.B.H.N. van den, Janssen A.P.A., Lichtman A., Liu Z.J., Pacher P., Stelt M. van der, Heitman L.H. & Hua T. (2023), Structural basis of selective cannabinoid CB2 receptor activation, Nature Communications 14(1): 1447.
- Patberg M., Isaak A., Füsser F., Ortiz Zacarías N.V., Vinnenberg L., Schulte J., Michetti L., Grey L., Horst C. van der, Hundehege P., Koch O., Heitman L.H., Budde T. & Junker A. (2021), Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists, European Journal of Medicinal Chemistry 226: 113838.
- Ortiz Zacarías N.V., Chahal K.K., Šimková T., Horst C. van der, Zheng Y., Inoue A., Theunissen E., Mallee L., Es D. van der, Louvel J., IJzerman A.P., Handel T.M., Kufareva I. & Heitman L.H. (2021), Design and characterization of an intracellular covalent ligand for CC chemokine receptor 2, Journal of Medicinal Chemistry 64(5): 2608-2621.
- Ruano‑Ordás D., Burggraaff L., Liu R., Horst C. van der, Heitman L.H., Emmerich M.T.M., Mendez J.R., Yevseyeva I. & Westen G.J.P. van (2019), A multiple classifier system identifies novel cannabinoid CB2 receptor ligands, Journal of Cheminformatics 11: 66.