Universiteit Leiden

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TRIXY Center of Expertise

About us

The multidisciplinary team of researchers, clinicians and medical practitioners within TRIXY ensures that important knowledge is gathered about vulnerabilities in individuals with an extra X or Y chromosome, in the field of physical, neurocognitive, emotional and social development, and risk for learning problems and behavioral problems. We need this knowledge to recognize early signs of developmental risks, provide psychoeducation, and to be able to provide the best support for children during their development, and to identify and develop interventions that are in line with the needs of children with X and Y chromosome trisomies.

Hanna Swaab (PhD) is professor in the field of Clinical Child and Adolescent Studies at Leiden university. She is also the director of LUBEC (outpatient clinic of Leiden University), and director of the TRIXY Center of Expertise. As a clinical neuropsychologist and psychotherapist, she has been active in science and care for children and adults with X and Y chromosome variations for 25 years.

Sophie van Rijn (PhD) ) is associate professor at the department of Clinical Child and Adolescent Studies at Leiden University and Chief Scientific Officer (CSO) of TRIXY. She has been active in scientific research of X and Y chromosome variations since 2001. She is head of the TRIXY Research lab, where neurocognitive, emotional, social and behavioral functioning is systematically investigated in individuals with an extra X of Y chromosome. Her goal is to increase and share scientific knowledge.

Claudia K├Ânig (MSc) ) is Chief Clinical Officer (CCO) of the TRIXY outpatient clinic of Leiden University (LUBEC). As a clinical psychologist and neuropsychologist, she is an expert in diagnosis and treatment for individuals with an extra X or Y, involving parents and teachers.  Her aims are to identify individual profiles of strengths and weaknesses in neurocognitive and behavioral skills, and to translate this to individual treatment plans.

Sabine Hannema (PhD) is pediatrician and endocrinologist at Leiden University Medical Center, and involved in the TRIXY Center of Expertise. She is specialized in medical care for children with X and Y chromosome variations. She is part of the multidisciplinairy team, which also involves child physiotherapist and occupational therapists. For questions regarding fertility treatment, there is a collaboration with the urologists-andrologists of the Erasmus Medical Center in Rotterdam.

Kimberly Kuiper (MSc) is junior researcher and clinical fellow at the TRIXY Center of Expertise. Her research is focused on developmental risks in children with an extra X or Y chromosome, aged 1 to 6 years. Kimberly is part of the clinical team and is involved in providing and improving diagnosis and treatment of neurobehavioral problems in children with X and Y chromosome trisomies.  She also works on translating scientific knowledge to clinical practice, providing psychoeducation, websites, brochures and books for parents and teachers.

Nienke Bouw (MSc) is a junior researcher at the TRIXY Center of Expertise at Leiden University. Her research is focused on developmental risks in children with an extra X or Y chromosome, aged 1 to 6 years. She teaches in the training program of the Clinical Child and Adolescent Studies at Leiden University, where she transfers up-to-date scientific knowledge about developmental risks in children with X and Y chromosome trisomies to future professionals in the clinical field.

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