Universiteit Leiden

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Research project

Efficient and flexible platform to isolate and study bacteriophages

We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.

Duration
2020  -   2021
Contact
Ariane Briegel
Funding
NWO Open Competition Domain Science - XS NWO Open Competition Domain Science - XS

Description

Viruses that only infect specific bacteria (bacteriophages) are promising agents to combat antibiotic-resistant bacterial infections. Bacteriophages have been utilized successfully to save lives in the past. However, the isolation, identification and characterization of suitable bacteriophages is a time-consuming process and requires up to several months to compile the appropriate bacteriophage mixtures. In the scope of this project, we propose to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples. The platform will be cost-efficient, using a minimal amount of sample and equipment to be broadly accessible to many laboratories.

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