Dissertation
Emerging approaches to study cell-cell interactions
The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds.
- Author
- Poulcharidis, D.
- Date
- 03 June 2020
- Links
- Thesis in Leiden Repository
The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds. In the first part the rate of lipid exchange was studied, during both natural cell-cell contacts and prolonged enforced contacts. In the second part lipidated coiled-coil peptides were used to study the behaviour and potential fusogenic behaviour of these compounds on cell-wall-deficient bacteria.