Most fascinating of medical statistics for me is that it operates on the border of two sciences. On one hand the world of statistics, a big discipline with a strong mathematical nature with numerous scientific journals, and on the other hand the big world of clinical and epidemiological research. Applying statistical methods in medical research demands a lot of creativity and professional skill. Having been working in this field for more than 25 years I still enjoy it very much. The field of medical research is very dynamic, more and more data are collected per individual and with a more complicated structure, continually giving rise to new challenges for biostatisticians. One of my special interests is meta-analysis. The medical literature is growing enormously and meta-analytical methods to combine, summarize and integrate the results are increasingly necessary. I hope to be able to contribute for a long time to the development of statistical methods in this and other areas.