Roman Koning
- Name
- Dr. R.I. Koning
- Telephone
- +31 71 526 9111
- r.i.koning@lumc.nl
Postdoc / guest
- Science
- NECEN
- Faculteit Geneeskunde
- Divisie 4
- Cel en Chemische biologie
- Hoolwerff, M. van; Ruiz, A.R.; Bouma, M.; Suchiman, H.E.D.; Koning, R.I.; Jost, C.R.; Mulder, A.A.; Freund, C.; Guilak, F.; Ramos, Y.F.M. & Meulenbelt, I. (2021), High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II, Science Advances 7(45).
- Zhou X.Q., Mytiliniou M., Hilgendorf J., Zeng Y., Papadopoulou P., Shao Y., Dominguez Maximilian P., Zhang L., Hesselberth M.B.S., Bos E., Siegler M.A., Buda F., Brouwer A.M., Kros A., Koning R.I., Heinrich D. & Bonnet S. (2021), Intracellular dynamic assembly of deep‐red emitting supramolecular nanostructures based on the Pt…Pt metallophilic interaction, Advanced materials 33(37).
- Zhou, X.Q.; Mytiliniou, M.; Hilgendorf, J.; Zeng, Y.; Papadopoulou, P.; Shao, Y.; Dominguez, M.P.; Zhang, L.Y.; Hesselberth, M.B.S.; Bos, E.; Siegler, M.A.; Buda, F.; Brouwer, A.M.; Kros, A.; Koning, R.I.; Heinrich, D. & Bonnet, S. (2021), Intracellular dynamic assembly of deep-red emitting supramolecular nanostructures based on the Pt horizontal ellipsis Pt metallophilic interaction, Advanced Materials 33(37).
- Wolff, G.; Limpens, R.W.A.L.; Zevenhoven-Dobbe, J.C.; Laugks, U.; Zheng, S.; Jong, A.W.M. de; Koning, R.I.; Agard, D.A.; Grunewald, K.; Koster, A.J.; Snijder, E.J. & Barcena, M. (2020), A molecular pore spans the double membrane of the coronavirus replication organelle, Science 369(6509): 1395-+.
- Kuipers, M.E.; Nolte-'t Hoen, E.N.M.; Ham, A.J. van der; Ozir-Fazalalikhan, A.; Nguyen, D.L.; Korne, C.M. de; Koning, R.I.; Tomes, J.J.; Hoffmann, K.F.; Smits, H.H. & Hokke, C.H. (2020), DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells, Journal of Extracellular Vesicles.
- Liu, S.J.; Gonzalez-Prieto, R.; Zhang, M.D.; Geurink, P.P.; Kooij, R.; Iyengar, P.V.; Dinther, M. van; Bos, E.; Zhang, X.B.; Devedec, S.E. le; Water, B. van de; Koning, R.I.; Zhu, H.J.; Mesker, W.E.; Vertegaal, A.C.O.; Ovaa, H.; Zhang, L.; Martens, J.W.M. & Dijke, P. ten (2020), Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGF beta-Induced Breast Cancer Metastasis, Clinical Cancer Research 26(6): 1460-1473.
- Deursen, P.M.G. van; Koning, R.I.; Tudor, V.; Moradi, M.A.; Patterson, J.P.; Kros, A.; Sommerdijk, N.A.J.M.; Koster, A.J. & Schneider, G.F. (2020), Graphene Liquid Cells Assembled through Loop-Assisted Transfer Method and Located with Correlated Light-Electron Microscopy, Advanced Functional Materials.
- Kuipers, M.E.; Nolte-'t Hoen, E.N.M.; Ham, A.J. van der; Ozir-Fazalalikhan, A.; Nguyen, D.L.; Korne, C.M. de; Koning, R.I.; Tomes, J.J.; Hoffmann, K.F.; Smits, H.H. & Hokke, C.H. (2020), DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells, JOURNAL OF EXTRACELLULAR VESICLES 9(1).
- Sapmaz, A.; Berlin, I.; Bos, E.; Wijdeven, R.H.; Janssen, H.; Konietzny, R.; Akkermans, J.J.; Erson-Bensan, A.E.; Koning, R.I.; Kessler, B.M.; Neefjes, J. & Ovaa, H. (2019), USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7, Nature Communications 10.
- Dzialo, E.; Rudnik, M.; Koning, R.I.; Czepiel, M.; Tkacz, K.; Baj-Krzyworzeka, M.; Distler, O.; Siedlar, M.; Kania, G. & Blyszczuk, P. (2019), WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts, International Journal of Molecular Sciences 20(6).
- Koning, R.I.; Koster, A.J. & Sharp, T.H. (2018), Advances in cryo-electron tomography for biology and medicine, Annals of Anatomy 217: 82-96.
- Cornelissen, R.; Boggild, A.; Eachambadi, R.T.; Koning, R.I.; Kremer, A.; Hidalgo-Martinez, S.; Zetsche, E.M.; Damgaard, L.R.; Bonne, R.; Drijkoningen, J.; Geelhoed, J.S.; Boesen, T.; Boschker, H.T.S.; Valcke, R.; Nielsen, L.P.; D'Haen, J.; Manca, J.V. & Meysman, F.J.R. (2018), The Cell Envelope Structure of Cable Bacteria, Frontiers in Microbiology 9.
- Schie, K.A. van; Kruithof, S.; Ooijevaar-de Heer, P.; Derksen, N.I.L.; Bovenkamp, F.S. van de; Saris, A.; Vidarsson, G.; Bentlage, A.E.H.; Jiskoot, W.; Romeijn, S.; Koning, R.I.; Bos, E.; Stork, E.M.; Koeleman, C.A.M.; Wuhrer, M.; Wolbink, G. & Rispens, T. (2018), Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies, Annals of the Rheumatic Diseases 77(10): 1471-1479.
- Howes, S.C.; Koning, R.I. & Koster, A.J. (2018), Correlative microscopy for structural microbiology, Current Opinion in Microbiology 43: 132-138.
- Kryshtafovych Andriy, Albrecht Reinhard, Basle Arnaud, Bule Pedro, Caputo Alessandro T., Carvalho Ana Luisa, Chao Kinlin L., Diskin Ron, Fidelis Krzysztof, Fontes Carlos M. G. A., Fredslund Folmer, Gilbert Harry J., Goulding Celia W., Hartmann Marcus D., Hayes Christopher S., Herzberg Osnat, Hill Johan C., Joachimiak Andrzej, Kohring Gert-Wieland, Koning Roman I., Lo Leggio Leila, Mangiagalli Marco, Michalska Karolina, Moult John, Najmudin Shabir, Nardini Marco, Nardone Valentina, Ndeh Didier, Pintacuda Guido, Postel Sandra, van Raaij Mark J., Roversi Pietro, Shimon Amir, Singh Abhimanyu K., Sundberg Eric J., Tars Kaspars, Zitzmann Nicole & Schwede Torsten (2018), Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016), Proteins 86: 27-50.
- Ugurlar, D.; Howes, S.C.; Kreuk, B.J. de; Koning, R.I.; Jong, R.N. de; Beurskens, F.J.; Schuurman, J.; Koster, A.J.; Sharp, T.H.; Parren, P.W.H.I. & Gros, P. (2018), Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement, Science 359(6377): 794-797.
- Breij, A. de; Riool, M.; Cordfunke, R.A.; Malanovic, N.; Boer, L. de; Koning, R.I.; Ravensbergen, E.; Franken, M.; Heijde, T. van der; Boekema, B.K.; Kwakman, P.H.S.; Kamp, N.; Ghalbzouri, A. el; Lohner, K.; Zaat, S.A.J.; Drijfhout, J.W. & Nibbering, P.H. (2018), The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms, Science Translational Medicine 10(423).
- Lenchenkov, N.S.; Glasbergen, G.; Kruijsdijk, C. van; Vulovic, M.; Bos, E.; Koning, R.I. & Cassiola, F. (2017), Characterisation of the size and swelling kinetics of copolymer nano-spheres extracted from an emulsion, Colloids and Surfaces A: Physicochemical and Engineering Aspects 535: 265-273.
- , G.S. du; Hathout, R.M.; Nasr, M.; Nejadnik, M.R.; Tu, J.; Koning, R.I.; Koster, A.J.; Slutter, B.; Kros, A.; Jiskoot, W.; Bouwstra, J.A. & Monkare, J. (2017), Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles, Journal of Controlled Release 266: 109-118.
- Basu, K.; Lajoie, D.; Aumentado-Armstrong, T.; Chen, J.; Koning, R.I.; Bossy, B.; Bostina, M.; Sik, A.; Bossy-Wetzel, E. & Rouiller, I. (2017), Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy, PLoS ONE 12(6).
- Shishovs, M.; Rumnieks, J.; Diebolder, C.; Jaudzems, K.; Andreas, L.B.; Stanek, J.; Kazaks, A.; Kotelovica, S.; Akopjana, I.; Pintacuda, G.; Koning, R.I. & Tars, K. (2016), Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages, Journal of Molecular Biology 428(21): 4267-4279.
- Koning, R.I.; Gomez-Blanco, J.; Akopjana, I.; Vargas, J.; Kazaks, A.; Tars, K.; Carazo, J.M. & Koster, A.J. (2016), Asymmetric cryo-EM reconstruction of phage MS2 reveals genome structure in situ, Nature Communications 7.
- Yague, P.; Willemse, J.; Koning, R.I.; Rioseras, B.; Lopez-Garcia, M.T.; Gonzalez-Quinonez, N.; Lopez-Iglesias, C.; Shliaha, P.V.; Rogowska-Wrzesinska, A.; Koster, A.J.; Jensen, O.N.; Wezel, G.P. van & Manteca, A. (2016), Subcompartmentalization by cross-membranes during early growth of Streptomyces hyphae, Nature Communications 7.
- Shakeel, S.; Westerhuis, B.M.; Domanska, A.; Koning, R.I.; Matadeen, R.; Koster, A.J.; Bakker, A.Q.; Beaumont, T.; Wolthers, K.C. & Butcher, S.J. (2016), Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis, Nature Communications 7.
- Celler K., Koning R.I., Willemse J., Koster A.J. & Wezel G.P. van (2016), Cross-membranes orchestrate compartmentalization and morphogenesis in Streptomyces, NATURE COMMUNICATIONS 7: 11836.
- Celler, K.; Koning, R.I.; Willemse, J.; Koster, A.J. & Wezel, G.P. van (2016), Cross-membranes orchestrate compartmentalization and morphogenesis in Streptomyces, Nature Communications 7.
- Reijer, P.M. den; Haisma, E.M.; Lemmens-den Toom, N.A.; Willemse, J.; Koning, R.A.; Demmers, J.A.A.; Dekkers, D.H.W.; Rijkers, E.; Ghalbzouri, A. el; Nibbering, P.H. & Wamel, W. van (2016), Detection of Alpha-Toxin and Other Virulence Factors in Biofilms of Staphylococcus aureus on Polystyrene and a Human Epidermal Model, PLoS ONE 11(1).
- Askes, S.H.C.; Mora, N.L.; Harkes, R.; Koning, R.I.; Koster, B.; Schmidt, T.; Kros, A. & Bonnet, S. (2015), Imaging the lipid bilayer of giant unilamellar vesicles using red-to-blue light upconversion, Chemical Communications 51(44): 9137-9140.
- Diebolder, C.A.; Halff, E.F.; Koster, A.J.; Huizinga, E.G. & Koning, R.I. (2015), Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation, Structure 23(12): 2349-2357.
- Diebolder, C.A.; Faas, F.G.A.; Koster, A.J. & Koning, R.I. (2015), Conical Fourier shell correlation applied to electron tomograms, Journal of Structural Biology 190(2): 215-223.
- Askes S.H.C., López Mora N., Harkes R., Koning R.I., Koster B., Schmidt T., Kros A. & Bonnet S.A. (2015), Imaging the lipid bilayer of giant unilamellar vesicles using red-to-blue light upconversion, Chemical Communications 51(44): 9137-9140.
- Beurskens, F.J.; Diebolder, C.A.; Jong, R. de; Voorhorst, M.; Verploegen, S.; Strumane, K.; Lindorfer, M.A.; Taylor, R.P.; Koning, R.I.; Saphire, E.O.; Burton, D.; Schuurman, J.; Gros, P. & Parren, P.W.H.I. (2014), Enhanced IgG hexamerization mediates efficient C1q docking and more rapid and substantial complement-dependent cytotoxicity; preclinical proof of concept, Molecular Immunology 61(2): 257-257.
- Koning, R.I.; Faas, F.G.; Boonekamp, M.; Visser, B. de; Janse, J.; Wiegant, J.C.; Breij, A. de; Willemse, J.; Nibbering, P.H.; Tanke, H.J. & Koster, A.J. (2014), MAVIS: An integrated system for live microscopy and vitrification.
- Diebolder, C.A.; Beurskens, F.J.; Jong, R.N. de; Koning, R.I.; Strumane, K.; Lindorfer, M.A.; Voorhorst, M.; Ugurlar, D.; Rosati, S.; Heck, A.J.R.; Winkel, J.G.J. van de; Wilson, I.A.; Koster, A.J.; Taylor, R.P.; Saphire, E.O.; Burton, D.R.; Schuurman, J.; Gros, P. & Parren, P.W.H.I. (2014), Complement Is Activated by IgG Hexamers Assembled at the Cell Surface, Science 343(6176): 1260-1263.
- Koning R.I., Faas F.G., Boonekamp M., Visser B. de, Janse J., Wiegant J.C.A.G., Breij A. de, Willemse J., Nibbering P.H., Tanke H.J. & Koster A.J. (2014), MAVIS: An integrated system for live microscopy and vitrification, Ultramicroscopy 143: 67-76.
- Koning, R.I.; Kutchoukov, V.G.; Hagen, C.W. & Koster, A.J. (2013), Nanofabrication of a gold fiducial array on specimen support for electron tomography., Ultramicroscopy 135: 99-104.
- Koning RI & Koster AJ (2013), Cellular nanoimaging by cryo electron tomography., Methods in Molecular Biology 950: 227-51.
- Janssens, M.; Mulder, A.A.; Smeden, J. van; Pilgram, G.S.K.; Wolterbeek, R.; Lavrijsen, A.P.M.; Koning, R.I.; Koster, A.J. & Bouwstra, J.A. (2013), Electron diffraction study of lipids in non-lesional stratum corneum of atopic eczema patients, BBA - Biomembranes 1828(8): 1814-1821.
- Koning, R.I.; Breij, A. de; Oostergetel, G.T.; Nibbering, P.H.; Koster, A.J. & Dijkshoorn, L. (2013), Cryo-electron tomography analysis of membrane vesicles from Acinetobacter baumannii ATCC19606(T), Research in Microbiology 164(5): 397-405.
- Celler, K.; Koning, R.I.; Koster, A.J. & Wezel, G.P. van (2013), Multidimensional View of the Bacterial Cytoskeleton, Journal of Bacteriology 195(8): 1627-1636.
- Faas, F.G.A.; Barcena, M.; Agronskaia, A.V.; Gerritsen, H.C.; Moscicka, K.B.; Diebolder, C.A.; Driel, L.F. van; Limpens, R.W.A.L.; Bos, E.; Ravelli, R.B.G.; Koning, R.I. & Koster, A.J. (2013), Localization of fluorescently labeled structures in frozen-hydrated samples using integrated light electron microscopy, Journal of Structural Biology 181(3): 283-290.
- Diebolder, C.A.; Koster, A.J. & Koning, R.I. (2012), Pushing the resolution limits in cryo electron tomography of biological structures, Journal of Microscopy 248(1): 1-5.
- Liu Z., Galli F., Waterreus W.J., Meulenbroek E.M., Koning R.I., Lamers G.E.M., Olsthoorn R.R.C.L., Pannu N.S., Oosterkamp T.H., Koster A.J., Dame R.T. & Abrahams J.P. (2012), Single-Walled Carbon Nanotubes as Scaffolds to Concentrate DNA for the Study of DNA-Protein Interactions, CHEMPHYSCHEM 13(6): 1569-1575.
- Liu, Z.F.; Galli, F.; Waterreus, W.J.; Meulenbroek, E.; Koning, R.I.; Lamers, G.E.M.; Olsthoorn, R.C.L.; Pannu, N.; Oosterkamp, T.H.; Koster, A.J.; Dame, R.T. & Abrahams, J.P. (2012), Single-walled carbon nanotubes as scaffolds to concentrate DNA for the study of DNA-protein interactions., ChemPhysChem 13(6): 1569-75.
- Wolinski, H.; Kolb, D.; Hermann, S.; Koning, R.I. & Kohlwein, S.D. (2011), A role for seipin in lipid droplet dynamics and inheritance in yeast, Journal of Cell Science 124(22): 3894-3904.
- Diebolder, C.A.; Koning, R.I.; Stutterheim, W.M.; Koster, A.J. & Gros, P. (2011), Cryo electron tomographic visualization of antigen bound antibodies and fitting of atomic models, Molecular Immunology 48(14): 1709-1709.
- Koning, R.I.; Cassimeris, L. & Tran, P. (2010), Cryo-Electron Tomography of Cellular Microtubules, MICROTUBULES: IN VIVO 97: 455-473.
- Koning RI & Koster AJ (2009), Cryo-electron tomography in biology and medicine, Annals of Anatomy 191(5): 427-445.
- Sepkhanova I, Drescher M, Meeuwenoord NJ, Limpens RWAL, Koning RI, Filippov DV & Huber M (2009), Monitoring Alzheimer Amyloid Peptide Aggregation by EPR, Applied Magnetic Resonance 36(2-4): 209-222.
- Graveland-Bikker JF, Koning RI, Koerten HK, Geels RBJ, Heeren RMA & de Kruif CG (2009), Structural characterization of alpha-lactalbumin nanotubes, Soft Matter 5(10): 2020-2026.
- van Driel LF, Valentijn JA, Valentijn KM, Koning RI & Koster AJ (2009), Tools for correlative cryo-fluorescence microscopy and cryo-electron tomography applied to whole mitochondria in human endothelial cells, European Journal of Cell Biology 88(11): 669-684.
- Versluis F, Tomatsu I, Kehr S, Fregonese C, Tepper AWJW, Stuart MCA, Ravoo BJ, Koning RI & Kros A (2009), Shape and Release Control of a Peptide Decorated Vesicle through pH Sensitive Orthogonal Supramolecular Interactions, Journal of the American Chemical Society 131(37): 13186+.
- Janssen BJC, Gomes L, Koning RI, Svergun DI, Koster AJ, Fritzinger DC, Vogel CW & Gros P (2009), Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex.
- Jiang LH, Schaffitzel C, Bingel-Erlenmeyer R, Ban N, Korber P, Koning RI, de Geus DC, Plaisier JR & Abrahams JP (2009), Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15, Journal of Molecular Biology 386(5): 1357-1367.
- Koning RI, Zovko S, Barcena M, Oostergetel GT, Koerten HK, Galjart N, Koster AJ & Mommaas AM (2008), Cryo electron tomography of vitrified fibroblasts: Microtubule plus ends in situ, Journal of Structural Biology 161(3).
- Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams JP, Koerten HK, Koning RI & Ban N (2007), Structure of the E-coli signal recognition particle bound to a translating ribosome (vol 444, pg 503, 2006), Nature 448(7157): 1076-1076.
- Vries, F.A.T. de; Zonneveld, J.B.M.; Groot, A.J. de; Koning, R.I.; Zeeland, A.A. van & Pastink, A. (2007), Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures, Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 615(1-2).
- Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams JP, Koerten HK, Koning RI & Ban N (2006), Structure of the E-coli signal recognition particle bound to a translating ribosome, Nature 444(7118).
- van den Worm SHE, Koning RI, Warmenhoven HJ, Koerten HK & van Duin J (2006), Cryo electron microscopy reconstructions of the Leviviridae unveil the densest icosahedral RNA packing possible, Journal of Molecular Biology 363(4).
- Plaisier JR, Koning RI, Koerten HK, van Heel M & Abrahams JP (2004), TYSON: Robust searching, sorting, and selecting of single particles in electron micrographs, Journal of Structural Biology 145(1-2).
- Plaisier JR, Koning RI, Koerten HK, van Roon AM, Thomassen EAJ, Kuil ME, Hendrix J, Broennimann C, Pannu NS & Abrahams JP (2003), Area detectors in structural biology, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 509(1-3).
No relevant ancillary activities