Pieter Reitsma
Professor Experimental Molecular Medicine
- Name
- Prof.dr. P.H. Reitsma
- Telephone
- +31 71 526 6985
- p.h.reitsma@lumc.nl
- ORCID iD
- 0000-0003-2207-1830
Professor Experimental Molecular Medicine
- Faculteit Geneeskunde
- Divisie 2
- Hematologie
- Hemostase
- Schreuder, M.; Reitsma, P.H. & Bos, M.H.A. (2020), Reversal Agents for the Direct Factor Xa Inhibitors: Biochemical Mechanisms of Current and Newly Emerging Therapies, Seminars in Thrombosis and Hemostasis 46(08): 986-998.
- Schreuder, M.; Poenou, G.; Strijbis, V.J.F.; Cheung, K.L.; Reitsma, P.H. & Bos, M.H.A. (2020), Evolutionary adaptations in pseudonaja textilis venom factor X induce zymogen activity and resistance to the intrinsic tenase complex, Thrombosis and Haemostasis 120(11): 1512-1523.
- Megy, K.; Downes, K.; Simeoni, I.; Bury, L.; Morales, J.; Mapeta, R.; Bellissimo, D.B.; Bray, P.F.; Goodeve, A.C.; Gresele, P.; Lambert, M.; Reitsma, P.; Ouwehand, W.H.; Freson, K. & Subcomm Genomics Thrombosis (2019), Curated disease-causing genes for bleeding, thrombotic, and platelet disorders: Communication from the SSC of the ISTH, Journal of Thrombosis and Haemostasis 17(8): 1253-1260.
- Heestermans, M.; Salloum-Asfar, S.; Streef, T.; Laghmani, E.; Salvatori, D.; Luken, B.M.; Zeerleder, S.S.; Spronk, H.M.H.; Korporaal, S.J.; Kirchhofer, D.; Wagenaar, G.T.M.; Versteeg, H.H.; Reitsma, P.H.; Renne, T. & Vlijmen, B.J.M. van (2019), Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils, Blood 133(19): 2090-2099.
- Schreuder, M.; Reitsma, P.H. & Bos, M.H.A. (2019), Blood coagulation factor Va's key interactive residues and regions for prothrombinase assembly and prothrombin binding, Journal of Thrombosis and Haemostasis 17(8): 1229-1239.
- Rietveld, I.M.; Lijfering, W.M.; Cessie, S. le; Bos, M.H.A.; Rosendaal, F.R.; Reitsma, P.H. & Cannegieter, S.C. (2019), High levels of coagulation factors and venous thrombosis risk: strongest association for factor VIII and von Willebrand factor, Journal of Thrombosis and Haemostasis 17(1): 99-109.
- Heestermans, M.; Jong, A. de; Tilburg, S. van; Reitsma, P.H.; Versteeg, H.H.; Spronk, H.M. & Vlijmen, B.J.M. van (2019), Use of "C9/11 Mismatch" Control Small Interfering RNA Reveals Sequence-Related Off-Target Effect on Coagulation of an Small Interfering RNA Targeting Mouse Coagulation Factor XII, Nucleic Acid Therapeutics: 1-6.
- Rietveld, I.M.; Bos, M.H.A.; Lijfering, W.M.; Li-Gao, R.F.; Rosendaal, F.R.; Reitsma, P.H. & Cannegieter, S.C. (2018), Factor V levels and risk of venous thrombosis: The MEGA case-control study, Research and Practice in Thrombosis and Haemostasis 2(2): 320-326.
- Spronk, H.M.H.; Padro, T.; Siland, J.E.; Prochaska, J.H.; Winters, J.; Wal, A.C. van der; Posthuma, J.J.; Lowe, G.; d'Alessandro, E.; Wenzel, P.; Coenen, D.M.; Reitsma, P.H.; Ruf, W.; Gorp, R.H. van; Koenen, R.R.; Vajen, T.; Alshaikh, N.A.; Wolberg, A.S.; Macrae, F.L.; Asquith, N.; Heemskerk, J.; Heinzmann, A.; Moorlag, M.; Mackman, N.; Meijden, P. van der; Meijers, J.C.M.; Heestermans, M.; Renne, T.; Dolleman, S.; Chayoua, W.; Ariens, R.A.S.; Baaten, C.C.; Nagy, M.; Kuliopulos, A.; Posma, J.J.; Harrison, P.; Vries, M.J.; Crijns, H.J.G.M.; Dudink, E.A.M.P.; Buller, H.R.; Henskens, Y.M.C.; Sjalander, A.; Zwaveling, S.; Erkuner, O.; Eikelboom, J.W.; Gulpen, A.; Peeters, F.E.C.M.; Douxfils, J.; Olie, R.H.; Baglin, T.; Leader, A.; Schotten, U.; Scaf, B.; Beusekom, H.M.M. van; Mosnier, L.O.; Vorm, L. van der; Declerck, P.; Visser, M.; Dippel, D.W.J.; Strijbis, V.J.; Pertiwi, K.; Cate-Hoek, A.J. ten & Cate, H. ten (2018), Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis, Thrombosis and Haemostasis 118(2): 229-250.
- Rietveld, I.M.; Schreuder, M.; Reitsma, P.H. & Bos, M.H.A. (2018), Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation, Thrombosis Research: Vascular Obstruction, Hemorrhage and Hemostasis 172: 104-109.
- Huisman, M.V.; Barco, S.; Cannegieter, S.C.; Gal, G. le; Konstantinides, S.V.; Reitsma, P.H.; Rodger, M.; Noordegraaf, A.V. & Klok, F.A. (2018), Pulmonary embolism, Nature Reviews Disease Primers 4.
- Heestermans, M.; Ouweneel, A.B.; Hassan, J.; Kloosterman, M.; Reitsma, P.H.; Gijbels, M.J.J.; Vlijmen, B.J.M. van & Eck, M. van (2018), Predilection of Low Protein C-induced Spontaneous Atherothrombosis for the Right Coronary Sinus in Apolipoprotein E deficient mice, Scientific Reports 8.
- Rein, N. van; Geus, K.S. de; Cannegieter, S.C.; Reitsma, P.H.; Meer, F.J.M. van der & Lijfering, W.M. (2018), Multi-dose drug dispensing as a tool to improve medication adherence: A study in patients using vitamin K antagonists, Pharmacoepidemiology and Drug Safety 27(1): 46-51.
- Cunha, M.L.R.; Meijers, J.C.M.; Rosendaal, F.R.; Vlieg, A.V.; Reitsma, P.H. & Middeldorp, S. (2017), Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism, PLoS ONE 12(11).
- Ouweneel, A.B.; Heestermans, M.; Verwilligen, R.A.F.; Gijbels, M.J.J.; Reitsma, P.H.; Eck, M. van & Vlijmen, B.J.M. van (2017), Silencing of Anticoagulant Protein C Evokes Low-Incident but Spontaneous Atherothrombosis in Apolipoprotein E-Deficient Mice-Brief Report, Arteriosclerosis, Thrombosis, and Vascular Biology 37(5): 782-+.
- Vossen, C.Y.; Vlieg, A.V.; Teruel-Montoya, R.; Salloum-Asfar, S.; Haan, H. de; Corral, J.; Reitsma, P.; Koeleman, B.P.C. & Martinez, C. (2017), Identification of coagulation gene 3 ' UTR variants that are potentially regulated by microRNAs, British Journal of Haematology 177(5): 782-790.
- Stegeman, B.H.; Vos, H.L.; Helmerhorst, F.M.; Rosendaal, F.R.; Reitsma, P.H. & Vlieg, A.V. (2017), Genetic variation in the first-pass metabolism of ethinylestradiol, sex hormone binding globulin levels and venous thrombosis risk, European Journal of Internal Medicine 42: 54-60.
- Verhoef, D.; Visscher, K.M.; Vosmeer, C.R.; Cheung, K.L.; Reitsma, P.H.; Geerke, D.P. & Bos, M.H.A. (2017), Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors, Nature Communications 8.
- Rein, N. van; Biedermann, J.S.; Meer, F.J.M. van der; Cannegieter, S.C.; Wiersma, N.; Vermaas, H.W.; Reitsma, P.H.; Kruip, M.J.H.A. & Lijfering, W.M. (2017), Major bleeding risks of different low-molecular-weight heparin agents: a cohort study in 12 934 patients treated for acute venous thrombosis, Journal of Thrombosis and Haemostasis 15(7): 1386-1391.
- Simeoni, I.; Stephens, J.C.; Hu, F.Y.; Deevi, S.V.V.; Megy, K.; Bariana, T.K.; Lentaigne, C.; Schulman, S.; Sivapalaratnam, S.; Vries, M.J.A.; Westbury, S.K.; Greene, D.; Papadia, S.; Alessi, M.C.; Attwood, A.P.; Ballmaier, M.; Baynam, G.; Bermejo, E.; Bertoli, M.; Bray, P.F.; Bury, L.; Cattaneo, M.; Collins, P.; Daugherty, L.C.; Favier, R.; French, D.L.; Furie, B.; Gattens, M.; Germeshausen, M.; Ghevaert, C.; Goodeve, A.C.; Guerrero, J.A.; Hampshire, D.J.; Hart, D.P.; Heemskerk, J.W.M.; Henskens, Y.M.C.; Hill, M.; Hogg, N.; Jolley, J.D.; Kahr, W.H.; Kelly, A.M.; Kerr, R.; Kostadima, M.; Kunishima, S.; Lambert, M.P.; Liesner, R.; Lopez, J.A.; Mapeta, R.P.; Mathias, M.; Millar, C.M.; Nathwani, A.; Neerman-Arbez, M.; Nurden, A.T.; Nurden, P.; Othman, M.; Peerlinck, K.; Perry, D.J.; Poudel, P.; Reitsma, P.; Rondina, M.T.; Smethurst, P.A.; Stevenson, W.; Szkotak, A.; Tuna, S.; Geet, C. van; Whitehorn, D.; Wilcox, D.A.; Zhang, B.; Revel-Vilk, S.; Gresele, P.; Bellissimo, D.B.; Penkett, C.J.; Laffan, M.A.; Mumford, A.D.; Rendon, A.; Gomez, K.; Freson, K.; Ouwehand, W.H. & Turro, E. (2016), A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders, Blood 127(23): 2791-2803.
- Heestermans, M.; Salloum-Asfar, S.; Salvatori, D.; Laghmani, E.; Luken, B.M.; Zeerleder, S.S.; Spronk, H.M.H.; Korporaal, S.J.; Wagenaar, G.T.M.; Reitsma, P.H. & Vlijmen, B.J.M. van (2016), Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice, Blood 127(21): 2630-2637.
- Heestermans, M.; Cunha, M.L.R.; Reitsma, P.H.; Zeerleder, S.S.; Middeldorp, S. & Vlijmen, B.J.M. van (2016), Circulating nucleosomes and elastase alpha 1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2, Thrombosis Research 142: 8-10.
- Tieken, C.; Verboom, M.C.; Ruf, W.; Gelderblom, H.; Bovee, J.V.M.G.; Reitsma, P.H.; Cleton-Jansen, A.M. & Versteeg, H.H. (2016), Tissue factor associates with survival and regulates tumour progression in osteosarcoma, Thrombosis and Haemostasis 115(5): 1025-1033.
- Tregouet, D.A.; Delluc, A.; Roche, A.; Derbois, C.; Olaso, R.; Germain, M.; Andrade, M. de; Tang, W.; Chasman, D.I.; Vlieg, A.V.; Reitsma, P.H.; Kabrhel, C.; Smith, N. & Morange, P.E. (2016), Is there still room for additional common susceptibility alleles for venous thromboembolism?, Journal of Thrombosis and Haemostasis 14(9): 1798-1802.
- Rein, N. van; Cannegieter, S.C.; Cessie, S. le; Rosendaal, F.R.; Reitsma, P.H.; Meer, F.J.M. van der & Lijfering, W.M. (2016), Statins and Risk of Bleeding: An Analysis to Evaluate Possible Bias Due to Prevalent Users and Healthy User Aspects, American Journal of Epidemiology 183(10): 930-936.
- Jong, W.M.C.; Cate, H. ten; Linnenbank, A.C.; Boer, O.J. de; Reitsma, P.H.; Winter, R.J. de & Zuurbier, C.J. (2016), Reduced acute myocardial ischemia-reperfusion injury in IL-6-deficient mice employing a closed-chest model, Inflammation Research 65(6): 489-499.
- Engert, A.; Balduini, C.; Brand, A.; Coiffier, B.; Cordonnier, C.; Dohner, H.; Wit, T.D. de; Eichinger, S.; Fibbe, W.; Green, T.; Haas, F. de; Iolascon, A.; Jaffredo, T.; Rodeghiero, F.; Salles, G.; Schuringa, J.J.; Andre, M.; Andre-Schmutz, I.; Bacigalupo, A.; Bochud, P.Y.; Boer, M. den; Bonini, C.; Camaschella, C.; Cant, A.; Cappellini, M.D.; Cazzola, M.; Celso, C. lo; Dimopoulos, M.; Douay, L.; Dzierzak, E.; Einsele, H.; Ferreri, A.; Franceschi, L. de; Gaulard, P.; Gottgens, B.; Greinacher, A.; Gresele, P.; Gribben, J.; Haan, G. de; Hansen, J.B.; Hochhaus, A.; Kadir, R.; Kaveri, S.; Kouskoff, V.; Kuhne, T.; Kyrle, P.; Ljungman, P.; Maschmeyer, G.; Mendez-Ferrer, S.; Milsom, M.; Mummery, C.; Ossenkoppele, G.; Pecci, A.; Peyvandi, F.; Philipsen, S.; Reitsma, P.; Ribera, J.M.; Risitano, A.; Rivella, S.; Ruf, W.; Schroeder, T.; Scully, M.; Socie, G.; Staal, F.; Stanworth, S.; Stauder, R.; Stilgenbauer, S.; Tamary, H.; Theilgaard-Monch, K.; Thein, S.L.; Tilly, H.; Trneny, M.; Vainchenker, W.; Vannucchi, A.M.; Viscoli, C.; Vrielink, H.; Zaaijer, H.; Zanella, A.; Zolla, L.; Zwaginga, J.J.; Martinez, P.A.; Akker, E. van den; Allard, S.; Anagnou, N.; Andolfo, I.; Andrau, J.C.; Angelucci, E.; Anstee, D.; Aurer, I.; Avet-Loiseau, H.; Aydinok, Y.; Bakchoul, T.; Balduini, A.; Barcellini, W.; Baruch, D.; Baruchel, A.; Bayry, J.; Bento, C.; Berg, A. van den; Bernardi, R.; Bianchi, P.; Bigas, A.; Biondi, A.; Bohonek, M.; Bonnet, D.; Borchmann, P.; Borregaard, N.; Braekkan, S.; Brink, M. van den; Brodin, E.; Bullinger, L.; Buske, C.; Butzeck, B.; Cammenga, J.; Campo, E.; Carbone, A.; Cervantes, F.; Cesaro, S.; Charbord, P.; Claas, F.; Cohen, H.; Conard, J.; Coppo, P.; Corrons, J.L.V.; Costa, L. da; Davi, F.; Delwel, R.; Dianzani, I.; Domanovic, D.; Donnelly, P.; Drnovsek, T.D.; Dreyling, M.; , M.Q. du; Dufour, C.; Durand, C.; Efremov, D.; Eleftheriou, A.; Elion, J.; Emonts, M.; Engelhardt, M.; Ezine, S.; Falkenburg, F.; Favier, R.; Federico, M.; Fenaux, P.; Fitzgibbon, J.; Flygare, J.; Foa, R.; Forrester, L.; Galacteros, F.; Garagiola, I.; Gardiner, C.; Garraud, O.; Geet, C. van; Geiger, H.; Geissler, J.; Germing, U.; Ghevaert, C.; Girelli, D.; Godeau, B.; Gokbuget, N.; Goldschmidt, H.; Goodeve, A.; Graf, T.; Graziadei, G.; Griesshammer, M.; Gruel, Y.; Guilhot, F.; Gunten, S. von; Gyssens, I.; Halter, J.; Harrison, C.; Harteveld, C.; Hellstrom-Lindberg, E.; Hermine, O.; Higgs, D.; Hillmen, P.; Hirsch, H.; Hoskin, P.; Huls, G.; Inati, A.; Johnson, P.; Kattamis, A.; Kiefel, V.; Kleanthous, M.; Klump, H.; Krause, D.; Hovinga, J.K.; Lacaud, G.; Lacroix-Desmazes, S.; Landman-Parker, J.; LeGouill, S.; Lenz, G.; Lilienfeld-Toal, M. von; Lindern, M. von; Lopez-Guillermo, A.; Lopriore, E.; Lozano, M.; MacIntyre, E.; Makris, M.; Makris, M.; Martens, J.; Mathas, S.; Matzdorff, A.; Medvinsky, A.; Menendez, P.; Migliaccio, A.R.; Miharada, K.; Mikulska, M.; Minard, V.; Montalban, C.; Montalembert, M. de; Montserrat, E.; Morange, P.E.; Mountford, J.; Muckenthaler, M.; Muller-Tidow, C.; Mumford, A.; Nadel, B.; Navarro, J.T.; Nemer, W. el; Noizat-Pirenne, F.; O'Mahony, B.; Oldenburg, J.; Olsson, M.; Oostendorp, R.; Palumbo, A.; Passamonti, F.; Patient, R.; Latour, R.P. de; Pflumio, F.; Pierelli, L.; Piga, A.; Pollard, D.; Raaijmakers, M.; Radford, J.; Rambach, R.; Rao, A.K.; Raslova, H.; Rebulla, P.; Rees, D.; Ribrag, V.; Rijneveld, A.; Rinalducci, S.; Robak, T.; Roberts, I.; Rodrigues, C.; Rosendaal, F.; Rosenwald, A.; Rule, S.; Russo, R.; Saglio, G.; Sanchez, M.; Scharf, R.E.; Schlenke, P.; Semple, J.; Sierra, J.; So-Osman, C.; Soria, J.M.; Stamatopoulos, K.; Stegmayr, B.; Stunnenberg, H.; Swinkels, D.; Barata, J.P.T.; Taghon, T.; Taher, A.; Terpos, E.; Thachil, J.; Tissot, J.D.; Touw, I.; Toye, A.; Trappe, R.; Traverse-Glehen, A.; Unal, S.; Vaulont, S.; Viprakasit, V.; Vitolo, U.; Wijk, R. van; Wojtowicz, A.; Zeerleder, S.; Zieger, B. & EHA Roadmap European Hematology Re (2016), The European Hematology Association Roadmap for European Hematology Research: a consensus document, Haematologica 101(2): 115-208.
- Groeneveld, D.J.; Bekkum, T. van; Cheung, K.L.; Dirven, R.J.; Castaman, G.; Reitsma, P.H.; Vlijmen, B. van & Eikenboom, J. (2015), No evidence for a direct effect of von Willebrand factor's ABH blood group antigens on von Willebrand factor clearance, Journal of Thrombosis and Haemostasis 13(4): 592-600.
- Groeneveld, D.J.; Bekkum, T.; Dirven, R.J.; Wang, J.W.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2015), Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease, Journal of Thrombosis and Haemostasis 13(10): 1854-1866.
- Stomp, W.; Reijnierse, M.; Kloppenburg, M.; Mutsert, R. de; Bovee, J.V.M.G.; Heijer, M. den; Bloem, J.L. & NEO Study Grp (2015), Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee, European Radiology 25(12): 3480-3487.
- Germain, M.; Chasman, D.I.; Haan, H. de; Tang, W.; Lindstrom, S.; Weng, L.C.; Andrade, M. de; Visser, M.C.H. de; Wiggins, K.L.; Suchon, P.; Saut, N.; Smadja, D.M.; Gal, G. le; Vlieg, A.V.; Narzo, A. di; Hao, K.; Nelson, C.P.; Rocanin-Arjo, A.; Folkersen, L.; Monajemi, R.; Rose, L.M.; Brody, J.A.; Slagboom, E.; Aissi, D.; Gagnon, F.; Deleuze, J.F.; Deloukas, P.; Tzourio, C.; Dartigues, J.F.; Berr, C.; Taylor, K.D.; Civelek, M.; Eriksson, P.; Psaty, B.M.; Houwing-Duitermaat, J.; Goodall, A.H.; Cambien, F.; Kraft, P.; Amouyel, P.; Samani, N.J.; Basu, S.; Ridker, P.M.; Rosendaal, F.R.; Kabrhel, C.; Folsom, A.R.; Heit, J.; Reitsma, P.H.; Tregouet, D.A.; Smith, N.L.; Morange, P.E. & Cardiogenics Consortium (2015), Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism, American Journal of Human Genetics 96(4): 532-542.
- Buitrago, L.; Rendon, A.; Liang, Y.P.; Simeoni, I.; Negri, A.; Filizola, M.; Ouwehand, W.H.; Coller, B.S. & ThromboGenomics Consortium (2015), alpha IIb beta 3 variants defined by next-generation sequencing: Predicting variants likely to cause Glanzmann thrombasthenia, Proceedings of the National Academy of Sciences 112(15): E1898-E1907.
- (2015), Pathogenesis of venous thromboembolism (and post-thrombotic syndrome).
- Salloum-Asfar, S.; Boelen, A.; Reitsma, P.H. & Vlijmen, B.J.M. van (2015), The Immediate and Late Effects of Thyroid Hormone (Triiodothyronine) on Murine Coagulation Gene Transcription, PLoS ONE 10(5).
- Kocaturk, B.; Tieken, C.; Vreeken, D.; Unlu, B.; Engels, C.C.; Kruijf, E.M. de; Kuppen, P.J.; Reitsma, P.H.; Bogdanov, V.Y. & Versteeg, H.H. (2015), Alternatively spliced tissue factor synergizes with the estrogen receptor pathway in promoting breast cancer progression, Journal of Thrombosis and Haemostasis 13(9): 1683-1693.
- Cleuren, A.C.A.; Blankevoort, V.T.; Diepen, J.A. van; Verhoef, D.; Voshol, P.J.; Reitsma, P.H. & Vlijmen, B.J.M. van (2015), Changes in Dietary Fat Content Rapidly Alters the Mouse Plasma Coagulation Profile without Affecting Relative Transcript Levels of Coagulation Factors, PLoS ONE 10(7).
- Rein, N. van; Cannegieter, S.C.; Rosendaal, F.R.; Reitsma, P.H. & Lijfering, W.M. (2014), Suspected survivor bias in case-control studies: stratify on survival time and use a negative control, Journal of Clinical Epidemiology 67(2): 232-235.
- Eshuis, W.J.; Eijck, C.H.J. van; Gerhards, M.F.; Coene, P.P.; Hingh, I.H.J.T. de; Karsten, T.M.; Bonsing, B.A.; Gerritsen, J.J.G.M.; Bosscha, K.; Bilgen, E.J.S.; Haverkamp, J.A.; Busch, O.R.C.; Gulik, T.M. van; Reitsma, J.B. & Gouma, D.J. (2014), Antecolic Versus Retrocolic Route of the Gastroenteric Anastomosis After Pancreatoduodenectomy A Randomized Controlled Trial, Annals of Surgery 259(1): 45-51.
- Wettinger, S.B.; Doggen, C.; Spek, A.; Felice, A.; Rosendaal, F.R. & Reitsma, P.H. (2014), A POLYMORPHISM IN THE GENE FOR PROTEIN TYROSINE PHOSPHATASE 1B IS ASSOCIATED WITH ALTERED LIPID PROFILE AND MYOCARDIAL INFARCTION, Atherosclerosis 235(2): E131-E131.
- Kleinegris, M.C.; Bos, M.H.A.; Roest, M.; Henskens, Y.; Cate-Hoek, A. ten; Deursen, C. van; Spronk, H.M.H.; Reitsma, P.H.; Groot, P.G. de; Cate, H. ten & Koek, G. (2014), Cirrhosis patients have a coagulopathy that is associated with decreased clot formation capacity, Journal of Thrombosis and Haemostasis 12(10): 1647-1657.
- Verhoef, D.; Yang, X.X.; Parthasarathy, S.; Reitsma, P.H.; Camire, R.M. & Bos, M.H.A. (2014), Functional implications of the unique disulfide bond in venom factor V from the Australian common brown snake Pseudonaja textilis, Toxin Reviews 33(1-2): 37-41.
- Vlieg, A.V.; Flinterman, L.E.; Bare, L.A.; Cannegieter, S.C.; Reitsma, P.H.; Arellano, A.R.; Tong, C.H.; Devlin, J.J. & Rosendaal, F.R. (2014), Genetic Variations Associated With Recurrent Venous Thrombosis, Circulation: Cardiovascular Genetics 7(6): 806-813.
- Wettinger, S.B.; Doggen, C.; Spek, A.; Felice, A.; Rosendaal, F.R. & Reitsma, P.H. (2014), MENDELIAN RANDOMIZATION IN INFLAMMATORY CONDITIONS - THE EXCEPTION RATHER THAN THE RULE?, Atherosclerosis 235(2): E221-E222.
- Rosendaal, F.R. & Reitsma, P.H. (2014), Meta-analysis, Journal of Thrombosis and Haemostasis 12(7): 1009-1009.
- Ocak, G.; Drechsler, C.; Vossen, C.Y.; Vos, H.L.; Rosendaal, F.R.; Reitsma, P.H.; Hoffmann, M.M.; Marz, W.; Ouwehand, W.H.; Krediet, R.T.; Boeschoten, E.W.; Dekker, F.W.; Wanner, C. & Verduijn, M. (2014), Single Nucleotide Variants in the Protein C Pathway and Mortality in Dialysis Patients, PLoS ONE 9(5).
- Groeneveld, D.J.; Wang, J.W.; Mourik, M.J.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2014), Storage and secretion of naturally occurring von Willebrand factor A domain variants, British Journal of Haematology 167(4): 529-540.
- Stuijver, D.J.F.; Elbers, L.P.B.; Zaane, B. van; Dekkers, O.M.; Spek, C.A.; Gerdes, V.E.A.; Reitsma, P.H. & Brandjes, D.P.M. (2014), The Effect of Levothyroxine on Expression of Inflammation-Related Genes in Healthy Subjects: A Controlled Randomized Crossover Study, Hormone and Metabolic Research 46(11): 789-793.
- Kocaturk, B.; Berg, Y.W. van den; Tiekena, C.; Mieog, J.S.D.; Kruijf, E.M. de; Engels, C.C.; Ent, M.A. van der; Kuppen, P.J.; Velde, C.J. van de; Ruf, W.; Reitsma, P.H.; Osanto, S.; Liefers, G.J.; Bogdanov, V.Y. & Versteeg, H.H. (2013), Alternatively spliced tissue factor promotes breast cancer growth in a beta 1 integrin-dependent manner, Proceedings of the National Academy of Sciences 110(28): 11517-11522.
- Wang, J.W.; Bouwens, E.A.M.; Pintao, M.C.; Voorberg, J.; Safdar, H.; Valentijn, K.M.; Boer, H.C. de; Mertens, K.; Reitsma, P.H. & Eikenboom, J. (2013), Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease, Blood 121(14): 2762-2772.
- Versteeg, H.H.; Heemskerk, J.W.M.; Levi, M. & Reitsma, P.H. (2013), NEW FUNDAMENTALS IN HEMOSTASIS, Physiological Reviews 93(1): 327-358.
- Safdar, H.; Cheung, K.L.; Salvatori, D.; Versteeg, H.H.; Laghmani, E.; Wagenaar, G.T.M.; Reitsma, P.H. & Vlijmen, B.J.M. van (2013), Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production, Blood 121(21): 4413-4416.
- Safdar, H.; Cleuren, A.C.A.; Cheung, K.L.; Gonzalez, F.J.; Vos, H.L.; Inoue, Y.; Reitsma, P.H. & Vlijmen, B.J.M. van (2013), Regulation of the F11, Klkb1, Cyp4v3 Gene Cluster in Livers of Metabolically Challenged Mice, PLoS ONE 8(9).
- Kocaturk, B.; Berg, Y.W. van den; Tieken, C.; Kuppen, P.J.K.; Ruf, W.; Reitsma, P.H.; Osanto, S.; Bogdanov, V.Y. & Versteeg, H.H. (2013), Alternatively spliced Tissue Factor fuels breast cancer growth by binding to a non-canonical site on beta1 integrins, Journal of Thrombosis and Haemostasis 11: 74-74.
- Kuijper, P.H.M.; Schellings, M.W.M.; Kerkhof, D. van de; Nicolaes, G.A.F.; Reitsma, P.; Halbertsma, F. & Dors, N. (2013), Two novel mutations in the prothrombin gene identified in a patient with compound heterozygous type 1/2 prothrombin deficiency, Haemophilia 19(5): E304-E306.
- Raps, M.; Helmerhorst, F.M.; Fleischer, K.; Dahm, A.E.A.; Rosendaal, F.R.; Rosing, J.; Reitsma, P.; Sandset, P.M. & Vliet, H.A.A.M. van (2013), The effect of different hormonal contraceptives on plasma levels of free protein S and free TFPI, Thrombosis and Haemostasis 109(4): 606-613.
- Pintao, M.C.; Ribeiro, D.D.; Bezemer, I.D.; Garcia, A.A.; Visser, M.C.H. de; Doggen, C.J.M.; Lijfering, W.M.; Reitsma, P.H. & Rosendaal, F.R. (2013), Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study, Blood 122(18): 3210-3219.
- Hengel, L.G. van den; Hellingman, A.A.; Nossent, A.Y.; Oeveren-Rietdijk, A.M. van; Vries, M.R. de; Spek, C.A.; Zonneveld, A.J. van; Reitsma, P.H.; Hamming, J.F.; Boer, H.C. de; Versteeg, H.H. & Quax, P.H.A. (2013), Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model, PLoS ONE 8(4).
- Hengel, L.G. van den; Osanto, S.; Reitsma, P.H. & Versteeg, H.H. (2013), Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide, Haematologica 98(1): 153-158.
- Hazewinkel, Y.; Reitsma, J.B.; Nagengast, F.M.; Vasen, H.F.; Os, T.A.M. van; Leerdam, M.E. van; Koornstra, J.J. & Dekker, E. (2013), Extracolonic cancer risk in patients with serrated polyposis syndrome and their first-degree relatives, Familial Cancer 12(4): 669-673.
- Rosendaal, F.R. & Reitsma, P.H. (2013), Is administering blood as useless as blood letting?, Journal of Thrombosis and Haemostasis 11(10): 1793-1793.
- Haarlem, M.P. van; Wise, M.W.; Gunst, A.W.; Heald, G.; McKean, J.P.; Hessels, J.W.T.; Bruyn, A.G. de; Nijboer, R.; Swinbank, J.; Fallows, R.; Brentjens, M.; Nelles, A.; Beck, R.; Falcke, H.; Fender, R.; Horandel, J.; Koopmans, L.V.E.; Mann, G.; Miley, G.; Rottgering, H.; Stappers, B.W.; Wijers, R.A.M.J.; Zaroubi, S.; Akker, M. van den; Alexov, A.; Anderson, J.; Anderson, K.; Ardenne, A. van; Arts, M.; Asgekar, A.; Avruch, I.M.; Batejat, F.; Bahren, L.; Bell, M.E.; Bell, M.R.; Bemmel, I. van; Bennema, P.; Bentum, M.J.; Bernardi, G.; Best, P.; Birzan, L.; Bonafede, A.; Boonstra, A.J.; Braun, R.; Bregman, J.; Breitling, F.; Brink, R.H. van de; Broderick, J.; Broekema, P.C.; Brouw, W.N.; Bruggen, M.; Butcher, H.R.; Cappellen, W. van; Ciardi, B.; Coenen, T.; Conway, J.; Coolen, A.; Corstanje, A.; Damstra, S.; Davies, O.; Deller, A.T.; Dettmar, R.J.; Diepen, G. van; Dijkstra, K.; Donker, P.; Doorduin, A.; Dromer, J.; Drost, M.; Duin, A. van; Eisloffel, J.; Enst, J. van; Ferrari, C.; Frieswijk, W.; Gankema, H.; Garrett, M.A.; Gasparin, F. de; Gerbers, M.; Geus, E. de; Griessmeier, J.M.; Grit, T.; Gruppen, P.; Hamaker, J.P.; Hassall, T.; Hoeft, M.; Holties, H.A.; Horneffer, A.; Horst, A. van der; Houwelingen, A. van; Huijgen, A.; Iacobelli, M.; Intema, H.; Jackson, N.; Jelic, V.; Jong, A. de; Kant, D.; Karastergiou, A.; Koers, A.; Kollen, H.; Kondratiev, V.I.; Kooistra, E.; Koopman, Y.; Koster, A.; Kuniyoshi, M.; Kramer, M.; Kuper, G.; Lambropoulos, P.; Law, C.; Leeuwen, J. van; Lemaitre, J.; Loose, M.; Maat, P.; Macario, G.; Markoff, S.; Masters, J.; McFadden, R.A.; McKay-Bukowski, D.; Meijering, H.; Meulman, H.; Mevius, M.; Millenaar, R.; Miller-Jones, J.C.A.; Mohan, R.N.; Mol, J.D.; Morawietz, J.; Morganti, R.; Mulcahy, D.D.; Mulder, E.; Munk, H.; Nieuwenhuis, L.; Nieuwpoort, R. van; Noordam, J.E.; Norden, M.; Noutsos, A.; Offringa, A.R.; Olofsson, H.; Omar, A.; Orru, E.; Overeem, R.; Paas, H.; Pandey-Pommier, M.; Pandey, V.N.; Pizzo, R.; Polatidis, A.; Rafferty, D.; Rawlings, S.; Reich, W.; Reijer, J.P. de; Reitsma, J.; Renting, G.A.; Riemers, P.; Rol, E.; Romein, J.W.; Roosjen, J.; Ruiter, M.; Scaife, A.; Schaaf, K. van der; Scheers, B.; Schellart, P.; Schoenmakers, A.; Schoonderbeek, G.; Serylak, M.; Shulevski, A.; Sluman, J.; Smirnov, O.; Sobey, C.; Spreeuw, H.; Steinmetz, M.; Sterks, C.G.M.; Stiepel, H.J.; Stuurwold, K.; Tagger, M.; Tang, Y.; Tasse, C.; Thomas, I.; Thoudam, S.; Toribio, M.C.; Tol, B. van der; Usov, O.; Veelen, M. van; Veen, A.J. van der; Veen, S. ter; Verbiest, J.P.W.; Vermeulen, R.; Vermaas, N.; Vocks, C.; Vogt, C.; Vos, M. de; Wal, E. van der; Weeren, R. van; Weggemans, H.; Weltevrede, P.; White, S.; Wijnholds, S.J.; Wilhelmsson, T.; Wucknitz, O.; Yatawatta, S.; Zarka, P.; Zensus, A. & Zwieten, J. van (2013), LOFAR: The LOw-Frequency ARray, Astronomy and Astrophysics 556.
- Bakker, B.; Reitsma, P.H.; Ooijen, H.J. van; Ham, R. van den; Rosendaal, F.R. & Lijfering, W.M. (2013), Optimal risk estimation for DVT requires measurement of coagulation protein concentrations, Journal of Thrombosis and Haemostasis 11: 215-215.
- Vencken, P.M.L.H.; Reitsma, W.; Kriege, M.; Mourits, M.J.E.; Bock, G.H. de; Hullu, J.A. de; Altena, A.M. van; Gaarenstroom, K.N.; Vasen, H.F.A.; Adank, M.A.; Schmidt, M.K.; Beurden, M. van; Zweemer, R.P.; Rijcken, F.; Slangen, B.F.M.; Burger, C.W. & Seynaeve, C. (2013), Outcome of BRCA1- compared with BRCA2-associated ovarian cancer: a nationwide study in the Netherlands, Annals of Oncology 24(8): 2036-2042.
- Rietveld, I.M.; Lijfering, W.M.; Bos, M.H.A.; Rosendaal, F.R.; Reitsma, P.H. & Cannegieter, S.C. (2013), Risk of venous thrombosis associated with coagulation factor VIII levels and the interrelation of other procoagulant and environmental risk factors, Journal of Thrombosis and Haemostasis 11: 843-843.
- Rein, N. van; Willem, L.M.; Cannegieter, S.C.; Rosendaal, F.R.; Reitsma, P.H. & Meer, J.M. van der (2013), Statin use and bleeding complications during treatment with vitamin K antagonists: a cohort study in 8188 patients with atrial fibrillation, Journal of Thrombosis and Haemostasis 11: 181-182.
- Hengel, L.G. van den; Berg, Y.W. van den; Reitsma, P.H.; Bos, M.H.A. & Versteeg, H.H. (2012), Evolutionary conservation of the tissue factor disulfide bonds and identification of a possible oxidoreductase binding motif.
- Reitsma, P.H.; Versteeg, H.H. & Middeldorp, S. (2012), Mechanistic View of Risk Factors for Venous Thromboembolism, Arteriosclerosis, Thrombosis, and Vascular Biology 32(3): 563-568.
- Safdar, H.; Cheung, K.L.; Vos, H.L.; Gonzalez, F.J.; Reitsma, P.H.; Inoue, Y. & Vlijmen, B.J.M. van (2012), Modulation of Mouse Coagulation Gene Transcription following Acute In Vivo Delivery of Synthetic Small Interfering RNAs Targeting HNF4 alpha and C/EBP alpha, PLoS ONE 7(6): -.
- Haan, H.G. de; Bezemer, I.D.; Doggen, C.J.; Cessie, S. le; Reitsma, P.H.; Arellano, A.R.; Tong, C.H.; Devlin, J.J.; Bare, L.A.; Rosendaal, F.R. & Vossen, C.Y. (2012), Multiple SNP testing improves risk prediction of first venous thrombosis, Blood 120(3): 656-663.
- Cleuren, A.C.A.; Oerle, R. van; Reitsma, P.H.; Spronk, H.M. & Vlijmen, B.J.M. van (2012), Long-term estrogen treatment of mice with a prothrombotic phenotype induces sustained increases in thrombin generation without affecting tissue fibrin deposition.
- Tieken, C.; Berg, Y.W. van den; Kruijf, E.M. de; Kuppen, P.J.K.; Reitsma, P.H.; Bogdanov, V.Y. & Versteeg, H.H. (2012), Interplay of tissue factor splice variants in thrombosis, Thrombosis Research 129: S169-S169.
- Wang, J.W.; Valentijn, J.A.; Valentijn, K.M.; Dragt, B.S.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2012), Formation of platelet-binding von Willebrand factor strings on non-endothelial cells.
- Wang, J.W.; Groeneveld, D.J.; Cosemans, G.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2012), Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation, Haematologica 97(6): 859-866.
- Kocaturk, B.; Tieken, C.; Reitsma, P.H.; Bogdanov, V.Y. & Versteeg, H.H. (2012), Alternatively spliced tissue factor triggers breast tumor growth, Thrombosis Research 129: S168-S169.
- Berg, Y.W. van den; Osanto, S.; Reitsma, P.H. & Versteeg, H.H. (2012), The relationship between tissue factor and cancer progression: insights from bench and bedside, Blood 119(4): 924-932.
- Wang, J.W.; Valentijn, K.M.; Boer, H.C. de; Dirven, R.J.; Zonneveld, A.J. van; Koster, A.J.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2011), Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease, Journal of Biological Chemistry 286(27): 24180-24188.
- Wang, J.W.; Bouwens, E.; Pintao, C.; Voorberg, J.; Valentijn, K.M.; Boer, H.C. de; Reitsma, P.H. & Eikenboom, J. (2011), Characterization of blood outgrowth endothelial cells derived from von Willebrand disease patients.
- Koenderman, J.S.; Bertina, R.M.; Reitsma, P.H. & Visser, M.C.H. de (2011), Over 50% of Dutch VTE families with protein C deficiency share a founder R272C mutation.
- Cleuren, A.C.A.; Sun, H.; Zhu, G.; Vlijmen, B.J.M. van; Reitsma, P.H.; Ginsburg, D. & Westrick, R.J. (2011), Early death of factor v leiden hemizygous mice: a fatal absence of wild type FV anticoagulant function.
- Goodeve, A.C.; Reitsma, P.H.; McVey, J.H. & Int Soc Thrombosis Haemostasis (2011), Nomenclature of genetic variants in hemostasis.
- Tanck, M.W.T.; Wichers, I.M.; Meijers, J.C.M.; Buller, H.R.; Reitsma, P.H. & Middeldorp, S. (2011), Quantitative trait locus for protein C in a family with thrombophilia, Thrombosis and Haemostasis 105(1): 199-201.
- Stegeman, B.H.; Vos, H.L.; Helmerhorst, F.M.; Vlieg, A.V.; Reitsma, P.H. & Rosendaal, F.R. (2011), SNPS in the SULT1E1 gene and the risk of oral contraceptive-associated venous thrombosis, Thrombosis Research 127: S124S124.
- Hengel, L.G. van den; Kocaturk, B.; Reitsma, P.H.; Ruf, W. & Versteeg, H.H. (2011), Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor, Blood 118(12): 3446-+.
- Kleinegris, M.C.F.; Kleinegris, M.C.F.; Loeffen, R.; Meer, F.J.M. van der; Reitsma, P.H.; Loubele, S.T.B.G.; Spronk, H.M.H. & Cate, H. ten (2011), Coagulation testing: influence of blood collection tube and pre-analytical storage temperature.
- Ribeiro, D.D.; Pintao, M.C.T.; Lijfering, W.M.; Reitsma, P.H. & Rosendaal, F.R. (2011), Free and Total Protein S Antigen Levels on the Risk of Venous Thrombosis: Results From the MEGA Study, Blood 118(21): 249-249.
- Pintao, C.; Winckers, K.; Brinkman, H.J.M.; Castoldi, E.; Hackeng, T.M. & Reitsma, P.H. (2011), Compound heterozygous protein s deficiency in a healthy woman.
- Berg, Y.W. van den & Reitsma, P.H. (2011), Not exclusively tissue factor: neutrophil extracellular traps provide another link between chemotherapy and thrombosis.
- Koenderman, J.S.; Bertina, R.M.; Reitsma, P.H. & Visser, M.C.H. de (2011), Factor IX-R338L (Factor IX Padua) screening in a Dutch population of sibpairs with early onset venous thromboembolism, Thrombosis Research 128(6): 603-603.
- Bare, L.A.; Arellano, A.R.; Tong, C.H.; Bezemer, I.; Lijfering, W.M.; Devlin, J.J.; Reitsma, P.H. & Rosendaal, F.R. (2011), Genetic variants of F11, statin use and venous thrombosis.
- Visser, M.C.H. de; Roshani, S.; Rutten, J.W.; Vlieg, A.V.; Vos, H.L.; Rosendaal, F.R. & Reitsma, P.H. (2011), Haplotypes of VKORC1, NQ01 and GGCX, their effect on activity levels of vitamin K-dependent coagulation factors, and the risk of venous thrombosis, Thrombosis and Haemostasis 106(3): 563-565.
- Pintao, M.C.; Roshani, S.; Visser, M.C.H. de; Tieken, C.; Tanck, M.W.T.; Wichers, I.M.; Meijers, J.C.M.; Rosendaal, F.R.; Middeldorp, S. & Reitsma, P.H. (2011), High levels of protein C are determined by PROCR haplotype 3.
- Wang, J.W.; Groeneveld, D.J.; Cosemans, G.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2011), Biogenesis of Weibel-Palade bodies in von Willebrand disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.
- Hengel, L.G. van den; Berg, Y.W. van den; Reitsma, P.H.; Bos, M.H.A. & Versteeg, H.H. (2011), Evolutionary Conservation of the Tissue Factor Disulfide Bonds and Identification of a Possible Oxidoreductase Binding Motif., Journal of Thrombosis and Haemostasis.
- Cleuren, A.C.A.; Postmus, I.; Vos, H.L.; Reitsma, P.H. & Vlijmen, B.J.M. van (2011), Progestins posses poor anti-estrogenic activity on murine hepatic coagulation gene transcription despite evident anti-estrogenic activity on uterine tissue, Thrombosis Research 128(2): 200-201.
- Safdar, H.; Cleuren, A.C.A.; Lei, C.K.; Reitsma, P.H. & Vlijmen, B.J.M. van (2011), Metabolic regulation of mouse liver F11 gene transcription and its relation to KLKB1 and CYP4V3 control.
- Schreijer, A.J.M.; Reitsma, P.H. & Cannegieter, S.C. (2010), High hematocrit as a risk factor for venous thrombosis. Cause or innocent bystander?, Haematologica 95(2): 182-184.
- Kruif, M.D. de; Limper, M.; Sierhuis, K.; Wagenaar, J.F.P.; Spek, C.A.; Garlanda, C.; Cotena, A.; Mantovani, A.; Cate, H. ten; Reitsma, P.H. & Gorp, E.C.M. van (2010), PTX3 predicts severe disease in febrile patients at the emergency department, Journal of Infection 60(2): 122-127.
- Cleuren, A.C.A.; Linden, I.K. van der; Visser, Y.P. de; Wagenaar, G.T.M.; Reitsma, P.H. & Vlijmen, B.J.M. van (2010), 17 alpha-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor alpha, Journal of Thrombosis and Haemostasis 8(8): 1838-1846.
- Cleuren, A.C.A.; Linden, I.K. van der; Visser, Y.P. de; Wagenaar, G.T.M.; Reitsma, P.H. & Vlijmen, B.J.M. van (2010), 17α-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor α., Journal of Thrombosis and Haemostasis 8(8): 1838-46.
- Safdar, H.; Inoue, Y.; Puijvelde, G.H. van; Reitsma, P.H. & Vlijmen, B.J.M. van (2010), The role of hepatocyte nuclear factor 4 alpha in regulating mouse hepatic anticoagulation and fibrinolysis gene transcript levels, Journal of Thrombosis and Haemostasis 8(12): 2839-2841.
- Schreijer, A.J.M.; Hoylaerts, M.F.; Meijers, J.C.M.; Lijnen, H.R.; Middeldorp, S.; Buller, H.R.; Reitsma, P.H.; Rosendaal, F.R. & Cannegieter, S.C. (2010), Explanations for coagulation activation after air travel, Journal of Thrombosis and Haemostasis 8(5): 971-978.
- Bezemer, I.D.; Bare, L.A.; Arellano, A.R.; Reitsma, P.H. & Rosendaal, F.R. (2010), Updated analysis of gene variants associated with deep vein thrombosis., Journal of the American Medical Association 303(5): 421-2.
- Kruif, M.D. de; Limper, M.; Gerritsen, H.; Spek, C.A.; Brandjes, D.P.M.; Cate, H. ten; Bossuyt, P.M.; Reitsma, P.H. & Gorp, E.C.M. van (2010), Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department, Critical Care Medicine 38(2): 457-463.
- Arellano, A.R.; Bezemer, I.D.; Tong, C.H.; Catanese, J.J.; Devlin, J.J.; Reitsma, P.H.; Bare, L.A. & Rosendaal, F.R. (2010), Gene variants associated with venous thrombosis: confirmation in the MEGA study, Journal of Thrombosis and Haemostasis 8(5): 1132-1134.
- Bezemer, I.D.; Bare, L.A.; Arellano, A.R.; Reitsma, P.H. & Rosendaal, F.R. (2010), Updated Analysis of Gene Variants Associated With Deep Vein Thrombosis, Journal of the American Medical Association 303(5): 421-422.
- van Stralen KJ, Stel VS, Reitsma JB, Dekker FW, Zoccali C & Jager KJ (2009), Diagnostic methods I: sensitivity, specificity, and other measures of accuracy, Kidney International 75(12): 1257-1263.
- Bezemer ID, Arellano AR, Tong CH, Rowland CM, Ireland HA, Bauer KA, Catanese J, Reitsma PH, Doggen CJM, Devlin JJ, Rosendaal FR & Bare LA (2009), F9 Malmo, factor IX and deep vein thrombosis, Haematologica 94(5): 693-699.
- Wichers IM, Tanck MWT, Meijers JCM, Lisman T, Reitsma PH, Rosendaal FR, Buller HR & Middeldorp S (2009), Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia, Thrombosis and Haemostasis 101(3): 465-470.
- Pomp ER, Doggen CJM, Vos HL, Reitsma PH & Rosendaal FR (2009), Polymorphisms in the protein C gene as risk factor for venous thrombosis, Thrombosis and Haemostasis 101(1): 62-67.
- Rosendaal FR & Reitsma PH (2009), Genetics of venous thrombosis, Journal of Thrombosis and Haemostasis 7: 301-304.
- Li Y, Bezemer ID, Rowland CM, Tong CH, Arellano AR, Catanese JJ, Devlin JJ, Reitsma PH, Bare LA & Rosendaal FR (2009), Genetic variants associated with deep vein thrombosis: the F11 locus, Journal of Thrombosis and Haemostasis 7(11): 1802-1808.
- van Minkelen R, Wettinger SB, de Visser MCH, Vos HL, Reitsma PH, Rosendaal FR, Bertina RM & Doggen CJM (2009), Haplotypes of the interleukin-1 receptor antagonist gene, interleukin-1 receptor antagonist mRNA levels and the risk of myocardial infarction, Atherosclerosis 203(1): 201-205.
- Pintao MC, Bezemer ID, Garcia AA, de Visser MCH, Doggen CJM, Reitsma PH & Rosendaal F (2009), Copy Number Variation of PROS1 and Protein S Deficiency Are Rare in a Population-Based Case-Control Study On Venous Thrombosis (MEGA study), Blood 114(22): 1229-1229.
- Monti M, Borensztajn KS, Pinotti M, Canella A, Branchini A, Marchetti G, Reitsma PH, Bernardi F & Spek CA (2009), Characterization of the intracellular signalling capacity of natural FXa mutants with reduced pro-coagulant activity, Thrombosis Research 123(6): 914-918.
- Niers TMH, Bruggemann LW, Klerk CPW, Muller FJM, Buckle T, Reitsma PH, Richel DJ, Spek CA, Van Tellingen O & Van Noorden CJF (2009), Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung, Clinical and Experimental Metastasis 26(3): 171-178.
- Pintao MC, Garcia AA, Borgel D, Alhenc-Gelas M, Spek CA, de Visser MCH, Gandrille S & Reitsma PH (2009), Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency, Human Genetics 126(3): 449-456.
- Niers TMH, Bruggemann LW, Van Sluis GL, Liu RD, Versteeg HH, Buller HR, Van Noorden CJF, Reitsma PH, Spek CA & Richel DJ (2009), Long-term thrombin inhibition promotes cancer cell extravasation in a mouse model of experimental metastasis, Journal of Thrombosis and Haemostasis 7(9): 1595-1597.
- Reitsma PH (2009), How to identify new genetic risk factors for VTE?, Thrombosis Research 123: S22S24.
- Pomp ER, Doggen CJ, Vos HL, Reitsma PH & Rosendaal FR (2009), Polymorphisms in the protein C gene as risk factor for venous thrombosis., Thrombosis and Haemostasis 101(1): 62-7.
- van Minkelen R, Wettinger SB, de Visser MC, Vos HL, Reitsma PH, Rosendaal FR, Bertina RM & Doggen CJ (2009), Haplotypes of the interleukin-1 receptor antagonist gene, interleukin-1 receptor antagonist mRNA levels and the risk of myocardial infarction.
- Rosendaal FR & Reitsma PH (2009), Genetics of venous thrombosis., Journal of Thrombosis and Haemostasis 7 Suppl 1: 301-4.
- Pintao MC, Roshani S, de Visser MCH, Tieken C, Tanck MWT, Buller HR, Wichers IM, Meijers JCM, Middeldorp S & Reitsma PH (2009), High Levels of Protein C Are Determinated by PROCR H3 in a Dutch Family, Blood 114(22): 841-842.
- Reitsma PH (2009), How to identify new genetic risk factors for VTE?, Thrombosis Research 123 Suppl 4: S22-4.
- Reitsma PH (2009), Genetic Risk Factors of Thrombosis, Blood 114(22): 1584-1584.
- Bezemer ID, Arellano AR, Tong CH, Rowland CM, Ireland HA, Bauer KA, Catanese J, Reitsma PH, Doggen CJ, Devlin JJ, Rosendaal FR & Bare LA (2009), F9 Malmö, factor IX and deep vein thrombosis.
- van den Berg YW, van den Hengel LG, Myers HR, Ayachi O, Jordanova E, Ruf W, Spek CA, Reitsma PH, Bogdanov VY & Versteeg HH (2009), Alternatively spliced tissue factor induces angiogenesis through integrin ligation, Proceedings of the National Academy of Sciences 106(46): 19497-19502.
- Wichers IM, Garcia AA, Tanck MWT, Middeldorp S & Reitsma PH (2009), No linkage for venous thrombosis at a candidate region on chromosome 18 in Dutch thrombophilic families, Journal of Thrombosis and Haemostasis 7(7): 1239-1240.
- ten Kate MK, Platteel M, Mulder R, Terpstra P, Nicolaes GAF, Reitsma PH, van der Steege G & van der Meer J (2008), PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations, Human Mutation 29(7).
- Bezemer ID, Bare LA, Doggen CJM, Arellano AR, Tong C, Rowland CM, Catanese J, Young BA, Reitsma PH, Devlin JJ & Rosendaal FR (2008), Gene variants associated with deep vein thrombosis, Journal of the American Medical Association 299(11).
- Bruggemann LW, Versteeg HH, Reitsma PH & Spek CA (2008), High factor VIIa levels do not promote tumor metastasis, Thrombosis and Haemostasis 99(4).
- Versteeg HH, Borensztajn KS, Kerver ME, Ruf W, Reitsma PH, Spek CA & Peppelenbosch MP (2008), TF : FVIIa-specific activation of CREB upregulates proapoptotic proteins via protease-activated receptor-2, Journal of Thrombosis and Haemostasis 6(9).
- Garcia AA & Reitsma PH (2008), Vkorc1 and the vitamin K cycle, Vitamins and Hormones 78.
- Reitsma PH & Rosendaal FR (2007), Past and future of genetic research in thrombosis, Journal of Thrombosis and Haemostasis 5.
- Tanck MWT, Wichers IM, Meijers JCM, Buller HR, Reitsma PH & Middeldorp S (2007), Evidence for QTLs influencing the endogenous thrombin potential (ETP) and protein C concentrations in a Dutch family with unexplained thrombophilia, Blood 110(11).
- Reitsma PH (2007), No praise for folly: genomics will never be useful in arterial thrombosis, Journal of Thrombosis and Haemostasis 5(3).
- Reitsma PH (2007), VKORC1 gene variation and venous thrombosis: 'another one bites the dust'?, Journal of Thrombosis and Haemostasis 5(10).
- Garcia AA, Van der Heijden JF, Meijers JCM, Rosendaal FR & Reitsma PH (2006), The relationship between ABO blood group and the risk of bleeding during vitamin K antagonist treatment, Journal of Thrombosis and Haemostasis 4(6).
- Bruggemann LW, Drijfhout JW, Reitsma PH & Spek CA (2006), Alternatively spliced tissue factor in mice: induction by Streptococcus pneumoniae, Journal of Thrombosis and Haemostasis 4(4).
- Boekholdt SM, Souverein OW, Tanck MWT, Hovingh GK, Kuivenhoven JA, Peters RIG, Jansen H, Schiffers PMH, van der Wall EE, Doevendans PA, Reitsma PH, Zwinderman AH, Kastelein JJP & Jukema JW (2006), Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels.
- Tjernberg P, Van Der Heijden JF, Eikenboom JCJ & Reitsma PH (2005), Evaluation of the von Willebrand factor Y1584C polymorphism as a potential risk factor for bleeding in patients receiving anticoagulant treatment with vitamin K antagonists, Journal of Thrombosis and Haemostasis 3(4).
- Reitsma PH, van der Heijden JF, Groot AP, Rosendaal FR & Buller HR (2005), A C1173T dimorphism in the VKORC1 gene determines coumarin Sensitivity and bleeding risk, PLoS Medicine 2(10).
- Wettinger SB, Doggen CJM, Spek CA, Rosendaal FR & Reitsma PH (2005), High throughput mRNA profiling highlights associations between myocardial infarction and aberrant expression of inflammatory molecules in blood cells, Blood 105(5).
- Rosendaal FR, Reitsma PH, Mollica L, Lane DA, Margaglione M, Merlini P & Ardissino D (2004), Genetic studies in complex disease, Journal of Thrombosis and Haemostasis 2(2).
- Hovinga JAK, Franco RF, Zago MA, Ten Cate H, Westendorp RGJ & Reitsma PH (2004), A functional single nucleotide polymorphism in the thrombin-activatable fibrinolysis inhibitor (TAFI) gene associates with outcome of meningococcal disease, Journal of Thrombosis and Haemostasis 2(1).
- Van Der Heijden JF, Rekke B, Hutten BA, Van Der Meer JM, Remkes MGH, Vermeulen M, Buller HR & Reitsma PH (2004), Non-fatal major bleeding during treatment with vitamin K antagonists: influence of soluble thrombomodulin and mutations in the propeptide of coagulation factor IX, Journal of Thrombosis and Haemostasis 2(7).
- Boekholdt SM, Peters RJG, de Maat MPM, Zwinderman AH, van der Wall EE, Reitsma PH, Jukema JW & Kastelein JJP (2004), Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events, American Heart Journal 147(1).
- Reitsma PH & Rosendaal FR (2004), Activation of innate immunity in patients with venous thrombosis: the Leiden Thrombophilia Study, Journal of Thrombosis and Haemostasis 2(4).
- Boekholdt SM, Agema WRP, Peters RJG, Zwinderman AH, van der Wall EE, Reitsma PH, Kastelein JJP & Jukema JW (2003), Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events, Circulation 107(19).
- Reiner AP, Rosendaal FR, Reitsma PH, Lemaitre RN, Pearce RM, Friedlander Y, Raghunathan TE, Psaty BM & Siscovick DS (2002), Factor V Leiden, prothrombin G20210A, and risk of sudden coronary death in apparently healthy persons, American Journal of Cardiology 90(1).
- van Aken BE, Reitsma PH & Rosendaal FR (2002), Interleukin 8 and venous thrombosis: evidence for a role of inflammation in thrombosis, British Journal of Haematology 116(1).
- Editor-in-chief Journal of Thrombosis and haemostasis