Doris Heinrich Lab (Biophysics of Cellular Dynamics)
Cell spread and cell migration in 3D gels
For decades, biologists have been using 2D cell culture to
study biological mechanisms, but growing evidence shows
that cellular signaling and function in 2D differs greatly from
what is seen in the 3D environment of multicellular
organisms. Therefore, we use 3D gels (both artificial and natural) to cellular
morphology and motility.