Universiteit Leiden

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Lecture

LED3 Lecture: Rewriting Protein Modifications

Date
Thursday 26 February 2026
Time
Location
Gorlaeus Building
Einsteinweg 55
2333 CC Leiden
Room
CM.1.26

About Christina Woo

Christina M. Woo is a Morris Kahn Associate Professor of Chemistry and Chemical Biology at Harvard University whose research combines chemical biology, organic synthesis, and mass spectrometry to understand how small molecules and protein modifications regulate cellular processes and inform drug discovery; she earned her B.A. in chemistry from Wellesley College and her Ph.D. from Yale, followed by postdoctoral work with Carolyn Bertozzi before joining Harvard’s faculty in 2016, and her innovative work has been recognized with awards such as the Sloan Research Fellowship, Camille-Dreyfus Teacher-Scholar Award, and David Y. Gin Young Investigator Award. Woo’s lab has made significant discoveries about how the E3 ligase adaptor cereblon (CRBN) recognizes endogenous C-terminal cyclic imide protein modifications as natural degradation signals, a finding that deepens our understanding of CRBN-based targeted protein degradation mechanisms and has broad implications for designing new therapeutic degraders and illuminating cellular quality control pathways.

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