Programme
Metabolomics as a tool to investigate natural products
| 10:00 – 11:00 | Introduction to metabolomics (Robert Verpoorte) |
| 11:00 – 12:30 | Application of metabolomics to medicinal plant research (Alvaro Viljoen) |
| 12:30 – 14:00 | Break |
| 14:00 – 15:30 | Metabolomics in human health and disease (Martin Giera) |
| 15:30 – 16:30 | Revisiting Traditional Chinese Medicine by Metabolomics (Mei Wang) |
How to extract and basic of data processing and multivariate data analysis
| 10:00 – 11:00 | Sample preparation (Hye Kyong Kim) |
| 11:00 – 12:30 | Basic chromatography theory for metabolomics (Erica G. Wilson) |
| 12:30 – 14:00 | Break |
| 14:00 – 15:00 | Basic of multivariate data analysis (Harald van Mil) |
| 15:00 – 16:00 | Chromatography and spectroscopy data processing for metabolomics (Jeroen Jansen) |
How to detect metabolites by chromatography and spectroscopy
| 10:00 – 11:30 | Gas Chromatography-based metabolomics: theory and applications (Joachim Kopka) |
| 11:30 – 13:00 | LC-MS Metabolomics: theory and applications (J. William Allwood) |
| 13:00 – 14:00 | Break |
| 14:00 – 15:00 | TLC application to medicinal plant metabolic fingerprinting (Tien Do) |
| 15:00 – 16:30 | NMR based metabolomics: theory and applications to food analysis (Jan Schripsema) |
Metabolomics applications in life sciences
| 10:00 – 11:00 | NMR-based profiling of intra – and extracellular metabolome (Sarantos Kostidis) |
| 11:00 – 12:30 | 11:00 – 12:30 Strategies for unambiguous identification of biomarkers (Jean-Luc Wolfender) |
| 12:30 – 14:00 | Break |
| 14:00 – 15:00 | 14:00 – 15:00 NMR-based profiling of intra – and extracellular metabolome (Sarantos Kostidis) |
| 15:00 – 16:30 | Metabolomics applications in agriculture and marine research (David Overy) |
Techniques in detail
| 10:00 – 11:00 | Ambient mass spectrometry applied in food safety, metabolomics, forensics and drug analysis (Teris van Beek) |
| 11:00 – 12:00 | Identification of Metabolites by MS spectrometry (Rob van der Heijden) |
| 12:00 – 14:00 | Break |
| 14:00 - 15:00 | Application of in-vivo NMR for plant physiology (François Mesnard) |
| 15:00-16:00 | Closing Remarks (Robert Verpoorte, Young Hae Choi) |
Easter holiday
LC-MS and NMR Measurements
| 11:00 – 12:00 | Sample Preparation and Extraction (pre-record Video) |
| 12:00 – 12:30 | Q & A for sample preparation and extraction |
| 14:00 – 15:00 | LC-MS and NMR measurements (pre-record Video) |
| 15:00 – 16:00 | Q & A for LC-MS and NMR measurements |
Data processing of LC-MS
| 11:00 – 12:00 | LC-MS data processing (Lina M. Bayona Maldonado) |
| 12:00 – 12:30 | Q & A for LC-MS data processing |
| 14:00 – 15:00 | NMR data processing based on Mnova NMR suite (Young Hae Choi) |
| 15:00 – 15:30 | Q & A for NMR data processing |
Identification by LC-MS and multivariate data analysis
| 11:00 – 12:00 | MetaboScape (Bruker) application to LC-MS metabolomics (Rob van der Heijden) |
| 12:00 – 12:30 | Q & A for the application of MetaboScape |
| 14:00 – 15:00 | Multivariate data analysis (PCA and PLS) based on SIMCA (Young Hae Choi) |
| 15:00 – 15:30 | Q & A for Multivariate data analysis |
Discussion
| 10:00 – 13:00 | Discussion the homework of multivariate data analysis (Young Hae Choi) |
Structural elucidation of amino acids I
| 10:00 – 12:00 | Structural elucidation of amino acids I-1 (Young Hae Choi) |
| 14:00 – 16:00 | Structural elucidation of amino acids I-2 (Young Hae Choi) |
Structural elucidation of amino acids II
| 10:00 – 12:00 | Structural elucidation of amino acids II-1 (Young Hae Choi) |
| 14:00 – 16:00 | Structural elucidation of amino acids II-2 (Young Hae Choi) |
Structural elucidation of amino acids III
| 10:00 – 12:00 | Structural elucidation of amino acids III-1 (Young Hae Choi) |
| 14:00 – 16:00 | Structural elucidation of amino acids III-2 (Young Hae Choi) |
15 April, 2021 (Thursday)
Structural elucidation of sugars-I
| 10:00 – 12:00 | Structural elucidation of sugars I-1 (Young Hae Choi) |
| 14:00 – 16:00 | Structural elucidation of sugars I-1 (Young Hae Choi) |
Structural elucidation of sugars-II
| 10:00 – 12:00 | Structural elucidation of sugars II-1 (Young Hae Choi) |
| 14:00 – 16:00 | Structural elucidation of sugars II-1 (Young Hae Choi) |