Here you can find our most recent research publications

 

Foks AC, van Puijvelde GHM, Wolbert J, Kröner MJ, Frodermann V, van der Heijden T, van Santbrink PJ, Boon L, Bot I, Kuiper J. CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice. Cardiovascular Research. 2016;111:252-61.

 

Benne N, van Duijn J, Kuiper J, Jiskoot W, Slütter B. Orchestrating immune responses: How size, shape and rigidity affect the immunogenicity of particulate vaccines. J Control Release. 2016;234:124-34.

 

van der Geest R, Ouweneel AB, van der Sluis RJ, Groen AK, Van Eck M, Hoekstra M. Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice. Toxicol Appl Pharmacol. 2016;306:1-7.

 

van der Velden D, Lagraauw HM, Wezel A, Launay P, Kuiper J, Huizinga T, Toes REM, Stoop J, Bot I. Mast cell depletion in the pre-clinical phase of collagen induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile. Arthritis Research & Therapy. 2016;18:138.

 

Louwe MC, Lammers B, Frias MA, Foks AC, de Leeuw LR, Hildebrand RB, Kuiper J, Smit JW, Van Berkel TJ, James RW, Geerling JJ, Rensen PC, Van Eck M. Abca1 deficiency protects the heart against myocardial infarction-induced injury. Atherosclerosis. 2016;251:159-63.

 

de Vries MR, Wezel A, Maassen JM, Kip P, Peters EA, Karper JC, Kuiper J, Bot I, Quax PHA. Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response. Scientific Reports. 2016;6:24248.

 

Ouweneel AB, Van Eck M. Lipoproteins as modulators of atherothrombosis: From endothelial function to primary and secondary coagulation. Vascul Pharmacol. 2016;82:1-10.

 

Frodermann V, van Duijn J, van Puijvelde GHM, van Santbrink PJ, Lagraauw HM, de Vries MR, Quax PHA, Bot I, Foks AC, de Jager SCA, Kuiper J. Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages. Journal of Internal Medicine. 2016;279:592-605.

 

Frodermann V, van Duijn J, van Pel M, van Santbrink PJ, Bot I, Kuiper J, de Jager SCA. Mesenchymal Stem Cells reduce atherosclerosis development. Scientific Reports. 2015;5:15559.

 

Lagraauw HM, Kuiper J, Bot I. Acute and chronic psychological stress as risk factors for cardiovascular disease: Insights gained from epidemiological, clinical and experimental studies. Brain, Behavior, and Immunity. 2015;50:18-30.

 

Shi GP, Bot I, Kovanen PT. Mast cells in human and experimental cardiometabolic diseases. Nat Rev Cardiol. 2015;12:643-658.

 

Wezel A, Welten SMJ, Razawy W, Lagraauw HM, de Vries MR, Kuiper J, Quax PHA, Nossent AY, Bot I. Inhibition of 14q32 microRNA miR-494 reduces atherosclerotic lesion development and increases plaque stability. Annals of Surgery. 2015;262:841-848.