Vidya Ganapathy
PhD candidate / guest
- Name
- Dr. S. Ganapathy
- Telephone
- +31 71 527 5270
- s.ganapathy@chem.leidenuniv.nl
PhD candidate / guest
- Faculty of Science
- Leiden Institute of Chemistry
- LIC/ES/Biophysical Organic Chemistry
- Grip W.J. de & Ganapathy S. (2022), Rhodopsins: an excitingly versatile protein species for research, development and creative engineering, Frontiers in Chemistry 10: 879609.
- Ganapathy S., Opdam L.V., Hontani Y., Frehan S., Chen Q., Hellingwerf K.J., Groot H.J.M. de, Kennis J.T.M. & Grip W.J. de (2020), Membrane matters: The impact of a nanodisc-bilayer or a detergent microenvironment on the properties of eubacterial rhodopsins: the impact of a nanodisc-bilayer or a detergent microenvironment on the properties of two eubacterial rhodopsins, Biochimica et Biophysica Acta (BBA) - Biomembranes 1862(2): 183113.
- Mei G.X., Mamaeva N., Ganapathy S., Wang P., Grip W.J. de & Rothschild K.J. (2020), Analog Retinal Redshifts Visible Absorption of QuasAr Transmembrane Voltage Sensors into Near-infrared, Photochemistry and Photobiology 96(1): 55-66.
- Chen Q., Arents J., Schuurmans J.M., Ganapathy S., Grip W.J. de, Cheregi O., Funk C., Branco Dos Santos F. & Hellingwerf K.J. (2019), Functional Expression of Gloeobacter Rhodopsin in PSI-Less Synechocystis sp. PCC6803, Frontiers in Bioengineering and Biotechnology 7: 67.
- Ganapathy S., Kratz S., Chen Q., Hellingwerf K.J., Groot H.J.M. de, Rothschild K.J. & Grip W.J. de (2019), Red-shifted and near-infrared active analog pigments based upon archaerhodopsin-3, Photochemistry and Photobiology 95(4): 959-968.
- Hontani Y., Ganapathy S., Frehan S., Kloz M., Grip W.J. de & Kennis J.T.M. (2019), Photoreaction Dynamics of Red-Shifting Retinal Analogues Reconstituted in Proteorhodopsin, Journal of Physical Chemistry B 123(19): 4242-4250.
- Chen Q., Arents J., Schuurmans J.M., Ganapathy S., Grip W.J. de, Cheregi O., Funk C., Dos Santos F.B. & Hellingwerf K.J. (2019), Combining retinal-based and chlorophyll-based (oxygenic) photosynthesis: Proteorhodopsin expression increases growth rate and fitness of a ∆PSI strain of Synechocystis sp. PCC6803, Metabolic Engineering 52: 68-76.
- Chen Q., Steen J.B. van der, Arents J.C., Hartog A.F., Ganapathy S., Grip W.J. de & Hellingwerf K.J. (2018), Deletion of sll1541 in Synechocystis sp. Strain PCC 6803 Allows Formation of a Far-Red-Shifted holo-Proteorhodopsin In Vivo, Applied and Environmental Microbiology 84(9): e02435.
- Hontani Y., Ganapathy S., Frehan S., Kloz M., Grip W.J. de & Kennis J.T.M. (2018), Strong pH-Dependent Near-Infrared Fluorescence in a Microbial Rhodopsin Reconstituted with a Red-Shifting Retinal Analogue, Journal of Physical Chemistry Letters 9: 6469-6474.
- Mei G., Mamaeva N., Ganapathy S., Wang P., Grip W.J. de & Rothschild K.J. (2018), Raman spectroscopy of a near infrared absorbing proteorhodopsin: Similarities to the bacteriorhodopsin O photointermediate, PLoS ONE 13(12): e0209506.
- Ganapathy S., Venselaar H., Chen Q., Groot H.J.M. de, Hellingwerf K.J. & Grip W.J. de (2017), Retinal-Based Proton Pumping in the Near Infrared, Journal of the American Chemical Society 139(6): 2338-2344.
- Chen Q., Arents J., Ganapathy S., Grip J.W. de & Hellingwerf K.J. (2017), Functional Expression of Gloeobacter Rhodopsin in Synechocystis sp. PCC6803, Photochemistry and Photobiology 93: 772–781.
- Buda F., Keijer T., Ganapathy S. & Grip W.J. de (2017), A Quantum-mechanical Study of the Binding Pocket of Proteorhodopsin: Absorption and Vibrational Spectra Modulated by Analogue Chromophores, Photochemistry and Photobiology 93(6): 1399-1406.
- Ganapathy S. (12 December 2017), Improvisations in phototrophy. Protein engineering and functional investigation of rhodopsin proton-pumps (Dissertatie. Institute of Chemistry (LIC), Science, Leiden University). Supervisor(s): Grip W.J. de & Groot H.J.M. de.
- Chen Q., Steen J.B. van der, Dekker H.L., Ganapathy S., Grip W.J. de & Hellingwerf K.J. (2016), Expression of holo-proteorhodopsin in Synechocystis sp PCC 6803, Metabolic Engineering 35: 83-94.
- Ganapathy S., Becheau O., Venselaar H., Frolich S., Steen J.B. van der, Chen Q., Radwan S., Lugtenburg J., Hellingwerf K.J., Groot H.J.M. de & Grip W.J. de (2015), Modulation of spectral properties and pump activity of proteorhodopsins by retinal analogues, Biochemical Journal 467(2): 333-343.
- Ganapathy S., Oostergetel G.T., Reus M., Tsukatani Y., Chew A.G.M., Buda F., Bryant D.A., Holzwarth A.R. & Groot H.J.M. de (2012), Structural variability in wild-type and bchQ bchR mutant chlorosomes of the green sulfur bacterium Chlorobaculum tepidum, Biochemistry 51(22): 4488-4498.
- Pandit A., Buda F., Gammeren A.J. van, Ganapathy S. & Groot H.J.M. de (2010), Selective chemical shift assignment of bacteriochlorophyll a in uniformly [C-13-N-15]-labeled light-harvesting 1 complexes by solid-state NMR in ultrahigh magnetic field, Journal of Physical Chemistry B 114(18): 6207-6215.
- Pandit A., Wawrzyniak P.K., Gammeren A.J. van, Buda F., Ganapathy S. & Groot H.J.M. de (2010), Nuclear magnetic resonance secondary shifts of a light-harvesting 2 complex reveal local backbone perturbations induced by its higher-order interactions, Biochemistry 49(3): 478-486.
- Ganapathy S., Sengupta S., Wawrzyniak P.K., Huber V., Buda F., Baumeister U., Wurthner F. & Groot H.J.M. de (2009), Zinc chlorins for artificial light-harvesting self-assemble into antiparallel stacks forming a microcrystalline solid-state material, Proceedings of the National Academy of Sciences 106(28): 11472-11477.
- Alia A., Ganapathy S. & Groot H.J.M. de (2009), Magic Angle Spinning (MAS) NMR: a new tool to study the spatial and electronic structure of photosynthetic complexes, Photosynthesis Research 102(2): 415-425.
- Ganapathy S., Oostergetel G.T., Wawrzyniak P.K., Reus M., Chew A.G.M., Buda F., Boekema E.J., Bryant D., Holzwarth A.R. & Groot H.J.M. de (2009), Alternating syn-anti bacteriochlorophylls form concentric helical nanotubes in chlorosomes, Proceedings of the National Academy of Sciences 106(21): 8525-8530.
- Ganapathy S., Reus M., Chew A.G.M., Bryant D.A., Holzwarth A.R. & Groot H.J.M. de (2008), Structural assessment of the bacteriochlorophyll d stacking in chlorosomes from a C. tepidum mutant with MAS NMR spectroscopy. In: Allen J.F., Gantt E., Golbeck J.H. & Osmond B. (Eds.), Photosynthesis: energy from the sun. Dordrecht: Springer. 247-251.
- Ganapathy S., Reus M., Chew A.G.M., Bryant D.A., Holzwarth A.R. & Groot H.J.M. de (2007), A comparative MAS NMR study of BChl d and BChl c producing mutants of C. tepidum. In: Allan J.F., Gantt E., Golbeck J.H. & Osmond B. (Eds.), Photosynthesis. Energy from the Sun. Dordrecht: Springer. 257-260.
- Ganapathy S., Reus M., Maqueo A.G., Bryant D., Holzwarth A.R. & Groot H.J.M. de (2007), Self-organization of BChl d in chlorosomes from 2D and 3D MAS NMR correlation spectroscopy, Photosynthesis Research 91(2-3): 165.
- Ganapathy S., Gammeren A.J. van, Hulsbergen F.B. & Groot H.J.M. de (2007), Probing secondary, tertiary, and quaternary structure along with protein-cofactor interactions for a helical transmembrane protein complex through 1H spin diffusion with MAS NMR spectroscopy, Journal of the American Chemical Society 129(6): 1504-1505.
- Ganapathy S., Boer I. de, Reus M., Chew A.G.M., Bryant D., Holzwarth A.R. & Groot H.J.M. de (2007), Validation of chlorosome structure models by NMR and shift analyses, Photosynthesis Research 91(2-3): 168.
No relevant ancillary activities