Jannik Rousel
Postdoc
- Name
- Dr. J. Rousel
- Telephone
- 071 5272727
- j.rousel@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0003-0986-3753
Jannik Rousel (M.Sc.) is a Postdoc at the Division of Drug Delivery Technology
Project: Systems dermatology of inflammatory diseases
Postdoc
- Faculty of Science
- LACDR
- Divisie Biotherapeutics
- Rousel J., Bergmans M.E., Bruijnincx L.J., Lin S., Kolk T.N. der, Bohoslavsky R., Yavuz Y., Klarenbeek N.B., Bouwstra J.A., Rissmann R. & Doorn M.B.A. van (2025), Mild psoriasis as a suitable model for proof-of-mechanism in a phase 1B setting: results from a double-blind placebo-controlled trial with guselkumab, British Journal of Clinical Pharmacology 91(12): 3378-3388.
- Rousel J., Bergmans M.E., Meulen L.W.J. van der, Pagan L., Bruin D.T. de, Kam M.L. de, Klarenbeek N.B., Bouwstra J.A., Seyger M.M.B., Reek J.M.P.A. van den, Niemeyer-van der Kolk T., Rissmann R., Doorn M.B.A. van & NGID consortium (2024), Guselkumab induction therapy demonstrates long-lasting efficacy in patients with mild psoriasis, results from a randomized, placebo-controlled exploratory clinical trial, Journal of The American Academy of Dermatology 90(2): 395-397.
- Rousel J., Mergen C., Schoones J.W., Niemeyer-van der Kolk T., Doorn M.B.A. van, Bouwstra J.A., Smeden J. van & Rissmann R. (2024), Similar alterations of the stratum corneum ceramide profile in atopic dermatitis, psoriasis, and ichthyosis: results from a systematic review and meta-analysis, Journal of Investigative Dermatology 144(10): 2311-2314.
- Rousel J., Mergen C., Bergmans M.E., Bruijnincx L.J., Kam M.L. de, Klarenbeek N.B., Niemeyer-van der Kolk T., Doorn M.B.A. van, Bouwstra J.A. & Rissmann R. (2024), Guselkumab treatment normalizes the stratum corneum ceramide profile and alleviates barrier dysfunction in psoriasis: results of a randomized controlled trial, Journal of Lipid Research 65(8): 100591.
- Rousel J., Mergen C., Bergmans ME., Klarenbeek N.B., Kolk T.N. der, Doorn M.B.A. van, Bouwstra J.A. & Rissmann R. (2024), Lesional Psoriasis is associated with alterations in the Stratum Corneum Ceramide profile and Concomitant decreases in Barrier Function, Experimental Dermatology 33(10): e15185.
- Rousel J. (24 October 2024), Non-invasive biomarkers for inflammatory skin diseases: towards systems dermatology (Dissertatie. Leiden Academic Centre for Drug Research (LACDR), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Rissmann R. & Bouwstra J.A., Doorn M.B.A. van.
- Nadaban A., Rousel J., El Yachioui D., Gooris G.S., Beddoes C.M., Dalgliesh R.M., Malfois M., Rissmann R. & Bouwstra J.A. (2023), Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models, Journal of Lipid Research 64(8): 100400.
- Rousel J., Nadaban A., Saghari M., Pagan L., Zhuparris A., Theelen B., Gambrah T., Wall H.E.C. van der, Vreeken R.J., Feiss G.L., Niemeyer-van der Kolk T., Burggraaf J. Doorn M.B.A. van, Bouwstra J.A. & Rissmann R. (2023), Lesional skin of seborrheic dermatitis patients is characterized by skin barrier dysfunction and correlating alterations in the stratum corneum ceramide composition, Experimental Dermatology 33(1): 14952.
- Rousel J., Saghari M., Pagan L., Nadaban A., Gambrah T., Theelen B., Kam M.L. de, Haakman J., Wall H.E.C. van der, Feiss G.L., Niemeyer-van der Kolk T., Burggraaf J., Bouwstra J.A., Rissmann R. & Doorn M.B.A. van (2023), Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial, International Journal of Molecular Sciences 24(18): 14315.
- Helder R.W.J., Rousel J., Boiten W.A., Gooris G.S., Nadaban A., Ghalbzouri A. el & Bouwstra J.A. (2023), The effect of PPAR isoform (de)activation on the lipid composition in full-thickness skin models, Experimental Dermatology 32(4): 469-478.
- Helder R.W.J., Rousel J., Boiten W.A., Gooris G.S., Nadaban A., El Ghalbzouri A. & Bouwstra J.A. (2021), Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting stearoyl-CoA desaturase-1, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1866(4): 158885.
- Grabarek A.D., Bozic U., Rousel J., Menzen T., Kranz W., Wuchner K., Jiskoot W. & Hawe A. (2020), What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress, Journal of Pharmaceutical Sciences 109(1): 871-880.