28 zoekresultaten voor “zebrafish” in de Publieke website
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
Promotie
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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underlying inflammation and infection control: insights from the zebrafish model
This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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Noortje DannenbergWiskunde en Natuurwetenschappen
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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Advancing Zebrafish Models in Proteomics
Promotie
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Two-photon multifocal microscopy for in vivo single-molecule and single-particle imaging
In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Promotie
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotie
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
Promotie
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New players in zebrafish caudal fin regeneration: differential requirement for protein-tyrosine phosphatases
Promotie
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Chemical approaches to control the in vivo behavior of nanomedicines
Lezing, Van Leeuwenhoek Lecture on BioScience
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Cell Observatory Mini-Symposium
Congres/symposium
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Plastic nanodeeltjes maken zebravislarven hyperactief
Nanoplastics beïnvloeden het gedrag van zebravislarven, blijkt uit onderzoek van Instituut Biologie Leiden (IBL) en het Centrum voor Milieuwetenschappen Leiden (CML). De onderzoekers zagen dat een bepaald type nanodeeltjes leidt tot stressreacties in de suikerhuishouding, met als gevolg hyperactiviteit…
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Marie Curie Trainingsnetwerk voor Instituut Biologie Leiden
Dr. Annemarie H. Meijer van het Instituut Biologie Leiden gaat een nieuw Marie Curie trainingsnetwerk coördineren dat 3,7 miljoen subsidie ontvangt van de Europese Commissie. Het vierjarige project begint in januari 2012 en heet: “FishForPharma: Training Network on Zebrafish Infection Models for Pharmaceutical…
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This Week’s Discoveries | 15 November 2016
Lezing
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Beat the Professor Pubquiz
Festival, Pubquiz
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This Week’s Discoveries | 13 March 2018
Lezing