Fate and toxicity of copper nanoparticles was related to the water chemistry of the environment and pristine size.

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.

Promotie

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

“Een partnerschap gebaseerd op water”, zo vatte Gerhard van den Top de relatie tussen Nederland en de Filipijnen samen in de 4e Louwes lezing. Hij benadrukte de cruciale rol van internationale en interculturele samenwerking in het managen van de complexe uitdagingen veroorzaakt door klimaatverandering.…

In this work, we attempt to answer the question:

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Promotor: E.F. Smets, Co-promotor: T.R. van Andel

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Promotores: H.A. Udo De Haes, P.M. Brakefield

Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.

Lezing

Wij hebben maar één maan, maar wist je dat sommige planeten er heel veel hebben? Jupiter bijvoorbeeld heeft er meer dan negentig! Kun je je voorstellen hoe de hemel eruit ziet voor een alien die op Jupiter woont? Een van die manen is Europa, die waarschijnlijk een oceaan van vloeibaar water heeft onder…

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Promotie

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

The global agri-food system plays a critical role in food security and environmental issues.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

A substance flow analysis, covering about 99 % of the flows of chlorinated substances in the Netherlands.

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotores: J. Kok, M. Chaudron (Chalmers University)

Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Op termijn zullen alle gebouwen een duurzame manier verwarmd en gekoeld worden, waardoor gas niet meer nodig is.

ICLON

Promotie

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Het dorp waar ik opgegroeid ben lag midden tussen de weilanden allemaal netjes begrensd door sloten. Op 10 minuten fietsafstand van mijn huidige woonplek is dit kenmerkende landschap eveneens te vinden.

In this thesis we present several methods to automate tomographic reconstruction algorithms and several novel tomographic reconstruction algorithms with the focus on being easily applicable and efficient to use.

In this thesis, we show that we can use Shimura’s CM theory to explicitly compute the Hilbert class field of any primitive quartic CM field.

In this thesis, several aspects of software debugging from automated crash reproduction to bug report analysis and use of contracts have been studied.

Promotie

Promotie

Promotie

Io is één van manen van Jupiter, de grootste planeet in het zonnestelsel. Jupiter heeft wel negentig manen. Vier daarvan zijn veel groter dan de andere, en van die vier staat Io het dichtst bij Jupiter. Van de andere manen staan er maar vier nog dichter bij Jupiter.

Lezing, NGL-lezing

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.