142 zoekresultaten voor “tumor quantification” in de Publieke website
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Computational optimisation of optical projection tomography for 3D image analysis
Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.
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Quantification of ecosystem services within river catchments
How can ecosystem services within river catchments be quantified in spatial and temporal explicit way?
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Risk Quantification and Modification in Older Patients with Colorectal Cancer
Promotie
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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The quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Stereotactic Radiotherapy of Intracranial Tumors
Promotie
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Fazel Abdolahpur MonikhWiskunde en Natuurwetenschappen
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inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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The quantification of growth hormone secretion
Promotie
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Tumor Biology & Immunology
Oratie
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Cellular tumor biology
Oratie
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Reconstructive Techniques in Musculoskeletal Tumor Surgery
Promotie
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Tumor biological characteristics of vestibular Schwannomas
Promotie
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Ocular responses to foreign corneal and tumor tissue
Promotie
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Ewa Snaar-Jagalska benoemd tot hoogleraar Cellulaire tumorbiologie
Met ingang van 1 april is Ewa Snaar-Jagalska benoemd tot hoogleraar Cellulaire tumorbiologie aan het Instituut voor Biologie, onderdeel van de Universiteit Leiden.
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Unraveling Vascular Tumors: Combining Molecular and Computational Biology
Promotie
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intra-cardiac vortex flow from 4D Flow MRI: Quantification, automatic identification and association with energy loss
Promotie
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Computed tomography coronary angiography: From quantification of coronary atherosclerosis to risk stratification of patients
Promotie
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The role of the tumor suppressor Lkb1 in energy homeostasis
Promotie
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Immune cell complexity in the tumor microenvironment of breast cancer
Promotie
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Novel Regulators of Prostate Cancer Stem Cells and Tumor Aggressiveness
Promotie
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T cell immunity against MHC-I low tumors in mouse models
Promotie
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inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Promotie
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Diagnostic and prognostic markers in tumor stage mycosis fungoides and Sézary syndrome
Promotie
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Exploring and Modulating the Tumor Immune Microenvironment Towards improving patient outcomes of immunotherapy in lung cancer
Promotie
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mutations in endometrial cancer – Insights into the biology of POLE-mutant tumors
Promotie
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stromal interactions in the pro-metastatic tumor microenvironment - Endoglin & TGF-β as (un)usual suspects
Promotie
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health-related quality of life in patients with brain tumors; Impact of tumor- and treatment-related factors
Promotie
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Genetic manipulation and genetic-based dissection of tumor-specific immunity
Promotie
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Applications of the tumor-stroma ratio; towards clinical implementation
Promotie
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using clinical available and innovative tumor-specific contrast agents
Promotie
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Onderzoeksproject 'QUAD'
Onderzoeksproject 'QUAD'
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water
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prognostic value of the tumor-stroma ratio in patients with breast cancer
Promotie
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Kankercellen onder de loep
Waarin verschilt een tumorcel van een gezonde cel? Die vraag proberen onderzoekers zo precies mogelijk te beantwoorden. Sommige verschillen kunnen dienen als aangrijpingspunt voor nieuwe therapieën.
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Patterns in natural systems
Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris
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Innovatie in behandeling en zorg
De behandeling en zorg rondom kanker wordt steeds geavanceerder. Zo kunnen chirurgen veel preciezer gaan opereren en komen er therapeutische vaccins om het eigen immuunsysteem van de patiënt aan te sporen de kanker te bestrijden. Ook wordt er gewerkt aan betere vroegdiagnostiek en is er veel meer oog…
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
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Medicijnen op maat
Er komen steeds meer medicijnen die op specifieke kenmerken van een tumor gericht zijn. De toepassing van chemotherapie wordt nog steeds verbeterd.
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Vacature: Postdoc voor het project ‘QUAD’
Voor het onderzoeksproject ‘Quantification, Administrative Capacity, and Democracy (QUAD)’ zoeken wij een postdoc onderzoeker.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.