1,645 zoekresultaten voor “transgenic animal model” in de Publieke website
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Surf Innovation Challenge Awards voor Shabaz Sultan en Simon Portegies Zwart
Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…
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Assistant, associate or full professor in Imaging and Artificial Intelligence (1fte)
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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Gibbs-non-Gibbs transitions and vector-valued integration
Promotor: W. T. F. den Hollander, F. H. J. Redig
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Understandig Sponsorship Involvement Outcomes in Partnership Models
Promotie
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The Metals Programme
Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.
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The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law
Op 23 juni 2019 verdedigde Zygimantas Juska zijn proefschrift 'The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law'. Het promotieonderzoek is begeleid door promotor prof. dr. T.R Ottervanger.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
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Motivatie ontrafeld: waarom blijven armoede, onrecht, discriminatie en zelfs genocide de mensheid teisteren?
Naar motivatie wordt al 100 jaar onderzoek verricht. En dat is niet verwonderlijk, want motivatie ligt aan de basis van ons bestaan. Waarom doen we de dingen die we doen? Waarom willen we iets, of stellen we juist uit? Maar ook in grote dingen: waarom worden we verliefd, kopen we een huis, starten we…
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Zebrafish as vertebrate model of Gaucher disease
Promotie
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Vondel en Vergilius: model voor een carrière
Lezing
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Abstract Behavioral Specification: unifying modeling and programming
Promotie
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Unraveling Temporal Processes using Probabilistic Graphical Models
Promotie
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On metrics and models for multiplex networks
Promotie
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Programmanormen
Het project programmanormen bevat richtlijnen voor de inrichting van het onderwijs van de Faculteit der Geesteswetenschappen
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‘Investeerdersrisico belemmert de energietransitie’
Met de huidige marktregels is het behoorlijk risicovol om in groene energie te investeren, en dat staat de strijd tegen klimaatverandering in de weg. Dat schrijft milieuwetenschapper Oscar Kraan in zijn proefschrift. Promotie op 25 april.
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Data Driven Modeling & Optimization of Industrial Processes
Promotie
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Research scientific programmer, Automated machine learning for spatio-temporal Earth Observation datasets
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Workshop: Metalearning and model management for data science
Lezing
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Meest diverse koraalriffen niet altijd best beschermd
Over de hele wereld staan koraalriffen onder druk. Zarinah Waheed onderzocht de riffen in Maleisië en komt tot de conclusie dat de bescherming van koraalriffen beter kan. Promotie op 22 november.
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotie
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Me, My Fiends, and I
A neuro-ecological perspective on adolescent prosocial development
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Probing Gravity at Cosmic Scales
The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.
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Aspects of cosmic acceleration
The focus of the dissertation
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.
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Quantum dot microcavity control of photon statistics
During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Sizing up protoplanetary disks
This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.
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The puzzle of protoplanetary disk masses
My work focuses on a class of astronomical objects called protoplanetary disks.
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Lasers, lenses and light curves: adaptive optics microscopy and peculiar transiting exoplanets
Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen
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CarbonCap
In the CarbonCap project, consumption oriented technological options and policy measures are identified as an addition to the present EU and world climate policy.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Topological phases and phase transitions in magnets and ice
The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.