212 zoekresultaten voor “transcriptional regulation” in de Publieke website
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Self-regulation models
... which builds on self-regulation and stress-regulation theories and considers the modification of cognitions as a mediator of therapeutic change.
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Public and Private Regulation of Financial Markets
How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?
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Regulation of signal transduction pathways by hypoxia in breast cancer subtypes
Promotie
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Unfolding the regulation of stress response pathways upon liver injury
Promotie
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From correlation to causation: data-driven exploration of transcriptional regulation using population genomics
Promotie
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Sex-specific post-transcriptional regulation of cardiovascular complications in diabetes
Promotie
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Investor protection : towards additional EU regulation of investment funds?
Dit proefschrift behandelt de vraag of er een level playing field is tussen Europese beleggers die beleggen in EU-beleggingsinstellingen en Europese beleggers die beleggen in Amerikaanse beleggingsinstellingen en, als dit niet het geval is, of de Europese wetgever aanvullende regelgeving zou moeten…
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Regulation of the arabidopsis AGC kinase PINOID by PDK1 and the microtubule cytoskeleton
Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.
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Bértoa & Van Biezen, The Regulation of Post-Communist Party Politics
In deze bundel wordt de regulering behandeld van politieke partijen in de post-communistische EU-landen, met name Bulgarije, Croatië, Tsjechië, Estland, Hongarije, Letland, Litouwen, Polen, Slowakije, Slovenië en Roemenië.
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Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking
Op 10 oktober 2019 verdedigde Laure d'Hondt haar proefschrift 'Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.
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Financial Market Regulation and Supervision in: The Law of the European Union
Matthias Haentjens, Jouke Tegelaar en Dorine Verheij schreven het hoofdstuk Financial Market Regulation and Supervision, dat recentelijk is gepubliceerd in het belangwekkende handboek The Law of the European Union (voorheen Kapteyn & VerLoren van Themaat).
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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PhD position to study regulation and transport of a novel anti-diabetic plant derived metabolite
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the
Op 12 september 2019 verdedigde Michiel Rhoen zijn proefschrift 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. Het promotieonderzoek is begeleid door promotoren prof.dr.mr.…
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Lustrumcongres Hazelhoff Centre: Public and Private Regulation of Financial Markets
Op 11 mei 2017 vond ter gelegenheid van zijn eerste lustrum het lustrumcongres van Hazelhoff Centre for Financial Law plaats met als thema ‘Public and Private Regulation of Financial Markets’.
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Professor Haentjens over 'Proportionality in European Banking Regulation'
Op 13 februari 2017 sprak professor Matthias Haentjens bij de Griekse centrale bank op het congres “Proportionality in European Banking Regulation”. Dit congres werd georganiseerd door de centrale bank van Griekenland in samenwerking met de Universiteit van Piraeus en het European Banking Institute…
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
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Winifred Gebhardt
Faculteit der Sociale Wetenschappen
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Conference on Private law and market regulation georganiseerd door de onderzoeksgroep Coherent Privaatrecht
Op vrijdag 2 december 2016 heeft een internationale onderzoeksconferentie plaatsgevonden in Leiden. Deze was georganiseerd door de onderzoeksgroep van Coherent Privaatrecht. De conferentie droeg de titel “Private law and market regulation – interaction, interference or inconsistency?”. Het centrale…
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Upcoming Research Conference on Private law and market regulation in Leiden
Op vrijdag 2 december vindt in Leiden een internationale, multidisciplinaire conferentie plaats gecentreerd rond onderzoek over burgerlijk recht en marktregulering. De conferentie draagt de titel “Private law and market regulation – interaction, interference or inconsistency?” en wordt georganiseerd…
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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European Union Regulation on Insolvency Proceedings: An Introductory Analysis (Vierde Editie)
Dit boek, geschreven door prof. mr. Bob Wessels (em.) en Ilya Kokorin LLM, , beschrijft en analyseert de Europese insolventieverordening (herschikt) ('EIR 2017’) die inwerking is getreden in juni 2017.
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Promotie
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Gene regulation in embryonic development
Promotie
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Exploring novel regulators and enzymes in salicylic acid-mediated plant defense
Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.
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Ethiek Commissie Pedagogische Wetenschappen
De Commissie Ethiek heeft als hoofdtaak alle voorgenomen gedragswetenschappelijk onderzoek van het Instituut Pedagogische Wetenschappen, te toetsen op criteria van ethisch verantwoord wetenschappelijk handelen.
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Action control
... which conceptualizes and investigates cognitive and affective processes with respect to their ultimate function: the control of voluntary action and self-regulation.
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Master Track Public Administration: Economics and Governance
Courses in English.
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Security by behavioural design
In 2021 heeft het NCSC de Universiteit Leiden gevraagd om een rapid review uit te voeren naar best practices en mogelijkheden voor vervolgonderzoek over de integratie van gedragswetenschappen in security by design methodologieën en projecten. Dit academische veld wordt security by behavioural design…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
- Lorentz workshop Risk Regulation and Society
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Regulation of Inflammation in Uveal Melanoma
Promotie
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Metabolic regulation of differentiation and maturation
Promotie
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Tolerance and Immune Regulation in Rheumatoid Arthritis
Promotie
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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Computational modeling of cellular dynamics in tumor cell migration
Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.
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Hebben banken mensenrechten?
Op dinsdag 1 oktober 2019 ontving het Hazelhoff Centre for Financial Law voor de negentiende Hazelhoff Guest Lecture Paul Sharma, managing director bij Alvarez & Marsal en co-head van praktijkgroep European Financial Industry Regulatory Advisory Services.
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Regulation of BMP and TGFβ Signaling Pathway in Cancer Progression
Promotie
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Regulation of TGF-β signaling and EMT in cancer progression
Promotie
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Cytokine-mediated regulation of immunity during persistent viral infection
Promotie