190 zoekresultaten voor “transcription regulation” in de Publieke website
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Functional analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice
Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis thaliana
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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Public and Private Regulation of Financial Markets
How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Investor protection : towards additional EU regulation of investment funds?
Dit proefschrift behandelt de vraag of er een level playing field is tussen Europese beleggers die beleggen in EU-beleggingsinstellingen en Europese beleggers die beleggen in Amerikaanse beleggingsinstellingen en, als dit niet het geval is, of de Europese wetgever aanvullende regelgeving zou moeten…
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Regulation of the arabidopsis AGC kinase PINOID by PDK1 and the microtubule cytoskeleton
Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.
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Bértoa & Van Biezen, The Regulation of Post-Communist Party Politics
In deze bundel wordt de regulering behandeld van politieke partijen in de post-communistische EU-landen, met name Bulgarije, Croatië, Tsjechië, Estland, Hongarije, Letland, Litouwen, Polen, Slowakije, Slovenië en Roemenië.
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Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking
Op 10 oktober 2019 verdedigde Laure d'Hondt haar proefschrift 'Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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PhD position to study regulation and transport of a novel anti-diabetic plant derived metabolite
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the
Op 12 september 2019 verdedigde Michiel Rhoen zijn proefschrift 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. Het promotieonderzoek is begeleid door promotoren prof.dr.mr.…
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotie
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Lustrumcongres Hazelhoff Centre: Public and Private Regulation of Financial Markets
Op 11 mei 2017 vond ter gelegenheid van zijn eerste lustrum het lustrumcongres van Hazelhoff Centre for Financial Law plaats met als thema ‘Public and Private Regulation of Financial Markets’.
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Professor Haentjens over 'Proportionality in European Banking Regulation'
Op 13 februari 2017 sprak professor Matthias Haentjens bij de Griekse centrale bank op het congres “Proportionality in European Banking Regulation”. Dit congres werd georganiseerd door de centrale bank van Griekenland in samenwerking met de Universiteit van Piraeus en het European Banking Institute…
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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Senior research analyst
Wiskunde en Natuurwetenschappen, Leids Instituut voor Onderzoek in de Natuurkunde (LION)
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Senior research analyst
Wiskunde en Natuurwetenschappen
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
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Winifred Gebhardt
Faculteit der Sociale Wetenschappen
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Upcoming Research Conference on Private law and market regulation in Leiden
Op vrijdag 2 december vindt in Leiden een internationale, multidisciplinaire conferentie plaats gecentreerd rond onderzoek over burgerlijk recht en marktregulering. De conferentie draagt de titel “Private law and market regulation – interaction, interference or inconsistency?” en wordt georganiseerd…
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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More JAZ in the orchestration of jasmonate-mediated plant defense
Prof.dr. J. Memelink
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European Union Regulation on Insolvency Proceedings: An Introductory Analysis (Vierde Editie)
Dit boek, geschreven door prof. mr. Bob Wessels (em.) en Ilya Kokorin LLM, , beschrijft en analyseert de Europese insolventieverordening (herschikt) ('EIR 2017’) die inwerking is getreden in juni 2017.
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Unravelling molecular mechanisms in transcription-coupled nucleotide excision repair
Promotie
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Master Track Public Administration: Economics and Governance
Courses in English.
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Regulation of arteriogenesis
Promotie
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Gene regulation in embryonic development
Promotie
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Ethiek Commissie Pedagogische Wetenschappen
De Commissie Ethiek heeft als hoofdtaak alle voorgenomen gedragswetenschappelijk onderzoek van het Instituut Pedagogische Wetenschappen, te toetsen op criteria van ethisch verantwoord wetenschappelijk handelen.
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Security by behavioural design
In 2021 heeft het NCSC de Universiteit Leiden gevraagd om een rapid review uit te voeren naar best practices en mogelijkheden voor vervolgonderzoek over de integratie van gedragswetenschappen in security by design methodologieën en projecten. Dit academische veld wordt security by behavioural design…
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Tolerance and Immune Regulation in Rheumatoid Arthritis
Promotie
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Metabolic regulation of differentiation and maturation
Promotie
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Fully funded Ph.D. position – novel chemical modalities
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR), LACDR PhD Portal
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Hebben banken mensenrechten?
Op dinsdag 1 oktober 2019 ontving het Hazelhoff Centre for Financial Law voor de negentiende Hazelhoff Guest Lecture Paul Sharma, managing director bij Alvarez & Marsal en co-head van praktijkgroep European Financial Industry Regulatory Advisory Services.
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Conferentie “Private law and market regulation – interaction, interference or inconsistency?”
Congres/symposium
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Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.