Promotor: Prof.dr. G.A. van der Marel, Co-Promotor: J.D.C. Codée

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Studievoorlichting, Experience day

Promotor: Prof.dr.ir. E. Deprettere

Promotor: Prof.dr. J. den Hertog

This study tests whether behavioural problems at a young age are related to early reading and mathematics development.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Kom naar onze online en oncampus events om ons beter te leren kennen!

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

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Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

LIACS is a partner in the EU Erasmus+ Curriculum Development for the Asian education system. The knowledge available in the field of Data Science and Artificial Intelligence education will be shared and adapted for the Asian market.

Festival, Diploma-uitreiking

Het onderzoek dat in dit proefschrift wordt beschreven gaat over de ontwikkeling van praktijkkennis van ervaren natuurkunde- scheikunde -en biologiedocenten in de context van de invoering van het vak Algemene Natuurwetenschappen (ANW) in de Tweede Fase van het voortgezet onderwijs.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

Hoe kan de methode om de gecombineerde effecten van metaal-gebaseerde chemische stoffetn te bepalen worden verbeterd?

Lesgeven is een complex beroep. Docenten nemen veel beslissingen, bijvoorbeeld over wat ze onderwijzen, hoe ze dit gaan onderwijzen en hoe ze hun lessen kunnen aanpassen aan de behoeften van leerlingen. Dit vraagt een voortdurende ontwikkeling van nieuwe kennis en vaardigheden om expertise in alle facetten…

Met meer dan 20.000 Omaanse studenten die Britse programma's volgen in 2017/2018, is het aantal transnationale studenten vrij aanzienlijk in Oman. De transnationale leeromgeving is nieuw voor praktisch al het onderwijzend personeel en voor de studenten. Antonia Lamers onderzocht hoe een TNE-onderwijs-…

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?

Promotor: Prof.dr. B.R. Katzy

Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Promotor: Prof.dr. R.M.H. Merks

Miriam Cohen verdedigde haar proefschrift genaamd “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” op 28 juni 2017. Ze schreef haar proefschrift onder supervisie van prof.dr. L.J. van den Herik en prof. dr. C. Stahn.

Prof.dr. Gert Jan Kramer is bij de Faculteit Wiskunde en Natuurwetenschappen in deeltijd benoemd tot hoogleraar Sustainable Energy. Kramer is en blijft daarnaast manager Energy Futures bij Shell. Tot zijn aantreden in Leiden was Kramer hoogleraar bij de TU Eindhoven.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

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Koper

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Dit proefschrift beschrijft de ontwikkeling van een beoordelingsprocedure voor docenten, toegespitst op beginnende eerstegraads docenten Engels.

Promotor: Prof.dr. B. van de Water