70 zoekresultaten voor “stability” in de Publieke website
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LIBC SYLVIUS Lecture: Balancing Brain Plasticity/Stability
Lezing
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
- PhD position 2 (Leiden University) – Spatial patterns and multi-stability (1.0 FTE)
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Michiel VeldhuisWiskunde en Natuurwetenschappen
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Noisy Patterns: Bridging the gap between stochastics and dynamics
In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…
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Insights into the mechanism of electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Electrocatalytic CO2 reduction toward liquid fuels : on heterogeneous electrocatalysts and heterogenized molecular catalysts
With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.
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Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Challenges for the Security and Stability of Cyberspace and their Impact upon Global Stability
Lezing
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Effects of heavy fields on inflationary cosmology
Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Resource allocation in networks via coalitional games
Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone
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On the random-matrix theory of Majorana fermions in topological superconductors
The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.
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Understanding functional dynamics and conformational stability of β-glycosidases
Promotie
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Deciphering the complex paramagnetic NMR spectra of small laccase
Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.
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Design, synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Aspects of cosmic acceleration
The focus of the dissertation
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Biophysical feedbacks between seagrasses and hydrodynamics in relation to grazing, water quality and spatial heterogeneity
Consequences for sediment stability and seston trapping
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotores: Prof.dr. G.A. van der Marel, M. van Heel
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Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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Blowup in the complex Ginzburg-Landau equation
Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer
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Leiden Institute for Brain and Cognition
Het Leiden Institute for Brain and Cognition (LIBC) is een Leids Universitair netwerk dat zich richt op wetenschappelijke valorisatie en outreach. Het LIBC maakt zich sterk voor het stimuleren van interdisciplinaire samenwerking op het gebied van hersenen en cognitie.
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Roadblocks & bypasses: Protection of genome stability by translesion DNA synthesis in C. elegans
Promotie
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Culturele Antropologie en Ontwikkelings-sociologie
Wij bestuderen de dagelijkse praktijk van individuen, groepen en gemeenschappen - zowel in Nederland als wereldwijd - om ze te plaatsen binnen de complexe processen van sociale en globale ontwikkeling. In Leiden zijn we gespecialiseerd in de gevolgen van globalisering op het gebied van milieu, sociale…
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Designing Ships using Constrained Multi-Objective Efficient Global Optimization
A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.
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SiTaSol
What are the life-cycle environmental impacts and risks to human health and ecosystems of a III-V/Si PV system? How can these be expected to change when the system is deployed at industrial scale? What are the most favourable recycling scenarios?
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water quality and spatial heterogeneity: consequences for sediment stability and seston trapping
Promotie
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Anthropogenic effects on links between macro-invertebrate diversity and ecosystem functioning
How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?
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Klimaatverandering stelt Afrikaanse grazers voor moeilijke keuze
Leeuwen beperken hun prooidieren, zoals zebra’s en gnoes, in hun mogelijkheden zich aan te passen aan een opwarmende aarde. Dat ontdekte Leidse onderzoeker Michiel Veldhuis van het Centrum voor Milieuwetenschappen in Leiden samen met internationale collega’s. Het onderzoek is op 1 juni in Nature Ecology…
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Gastcollege Jeroen Dijsselbloem
Op woensdag 21 maart gaf Jeroen Dijsselbloem, voormalig minister van Financiën en voormalig voorzitter van de Eurogroep en van de Raad van Bestuur van de ESM (European Stability Mechanism), een gastcollege aan de Faculteit Governance and Global Affairs.
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Full Professor in Artificial Intelligence and Data Theory
Geneeskunde/LUMC, Wiskunde en Natuurwetenschappen
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PhD in physical chemistry: operando spectroscopy on IrOx and RuOx electrocatalysts
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Regulering schaduwbankwezen vanuit Chinees perspectief
Op 24 mei 2017 ontving het Hazelhoff Centre for Financial Law Shen Wei, decaan en hoogleraar aan Shandong University School of Law in China, voor de veertiende Hazelhoff Guest Lecture.
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PhD candidate in iPSCs pluripotency, differentiation potential and safety assessments
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Het 'The Hague Program for Cyber Norms' verwelkomt gastonderzoeker Caitríona Heinl
Wij zijn zeer verheugd Caitriona Heinl te verwelkomen als gastonderzoeker voor het The Hague Program for Cyber Norms bij het Institute of Security and Global Affairs van de Universiteit Leiden, van 22 januari tot 16 februari 2018.
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Frederique Visser wint Fruinprijs 2020
Er worden veel goede afstudeerscripties geschreven door de studenten die hun Leidse geschiedenisopleiding ermee afronden. Alleen de allerbeste scripties worden voorgedragen voor de Fruinprijs: de jaarlijkse prijs voor de beste onderzoeksmaster-, master- of Europaeumscriptie van de Opleiding Geschied…
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Materiaal gebouwd van tandwielen
Een speciaal ontworpen systeem van tandwielen is flexibel aan één kant en stijf aan de andere. Dit zijn robuuste eigenschappen van de structuur, die zelfs geldig blijven bij fabricagefouten. Dit opkomende onderzoeksveld kan leiden tot nieuwe manieren om tandwielsystemen te ontwerpen, zoals satelliettrackers…