529 zoekresultaten voor “single cell transcriptomics” in de Publieke website
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Structural characterization of the cell envelope of Actinobacteria under changing environments
Promotie
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Airway epithelial cell cultures for studying obstructive lung disease: Effects of IL‐13 and cigarette smoke
Promotie
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Overcoming barriers to T cell activation, infiltration and function in tumors
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Red blood cell transfusions in hemato-oncological patients: don't iron out the consequences
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
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Immune modulation by schistosomes:mechanisms of regulatory B cell induction and inhibition of allergic asthma
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis
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Clinical and Immunological Outcome after Paediatric Stem Cell Transplantation for Inborn Errors of Immunity
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hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Promotie
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Biology of cytokine-induced hematopoietic stem and progenitor cell mobilization
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Optimization of suntinib treatment in metastatic renal cell carcinoma: pharmacogenetic evidence and challenges
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
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Regulation of cell cycle progression by small ubiquitin-like modifiers
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Towards Functional Analysis of Cerebrovascular Cell Types Derived from Human Induced Pluripotent Stem Cells
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Fluorescent in vivo models for hematopoietic stem cell and lymphoid lineage analysis
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Assistant, associate or full professor in Imaging and Artificial Intelligence (1fte)
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Suppressing a Sea of Starlight: Enabling technology for the direct imaging of exoplanets
Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik
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Engagement of citizens and public professionals in the co-production of public services
The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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Cathodic corrosion
Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.
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Photocatalytic redox reactions at the surface of liposomes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Interaction of oxygen and carbon monoxide with Pt(111) at intermediate pressure and temperature: revisiting the fruit fly of surface science
Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink
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Services on Environmental Statistics and Accounts
What is the best way to combine the environmental and economic data and how can we create an operational system to do so, thereby supporting the delivery of data to the Data centres on Products and Resources?
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Systematic, phylogenetic and pollination studies of Specklinia (Orchidaceae)
Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Pharmacogenomics in Drug Development: Implementation and Application of PKPD Model Based Approaches
Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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a beat: studying cardiac rhythm with human pluripotent stem cell-derived cardiomyocytes
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T cell immunity against MHC-I low tumors in mouse models
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
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Immune regulation by CD4+CD49b+ T cells & B cell responses in arthritis
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In vitro and in vivo models for studying endothelial cell development and hereditary hemorrhagic telangiectasia
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Clinical determinants of red cell alloimmunízation: implications for preventative antigen matching strategies
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
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Targeting Chondrosarcoma and Osteosarcoma Cell metabolism -The IGF pathway and beyond
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
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Mast cell mediated immune modulation in experimental Rheumatoid Arthritis and atherosclerosis
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Insights from modeling metabolism and amoeboid cell motility in the immune system
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1,8 miljoen voor onderzoek naar hoe een stamcel een kraakbeencel wordt
Wetenschappers van het LUMC en de Universiteit Twente krijgen 1,8 miljoen euro ENW-Groot-subsidie van NWO om uit te zoeken hoe stamcellen uitgroeien tot specifieke weefsels, zoals kraakbeen. Deze kennis is noodzakelijk om regeneratieve geneeskunde met stamcellen voor artrose werkelijkheid te maken.
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Adsorption and Catalysis on Pt and Pd Monolayer-modified Pt Single Crystal Electrodes
Promotie