Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

In het schoolvak scheikunde is de concept-context benadering ingevoerd. Hans Vogelzang onderzocht of de Scrum-methodologie kan helpen bij het vormgeven van lessen met deze benadering.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotie

Stimuleren van Prestaties en Motivatie in de Eerste Jaren van het Voortgezet Onderwijs

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Centraal in dit proefschrift staan de perspectieven van docenten met betrekking tot zelfstandig leren.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

In deze studie wordt verslag gedaan van een onderzoek naar de ontwikkeling van de praktijkkennis bij elf docenten Nederlands. Zij ontwikkelden en implementeerden concept-contextrijk onderwijs met behulp van actieonderzoek.

Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

Teaching reading comprehension in secondary education

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

The World Teachers Programme is conducted in close cooperation with EP-Nuffic and partner schools.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

Lezing

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Lezing

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

Promotie

Promotie

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

PUMA aims at composing a geological map of the urban mine of Amsterdam for a selection of metals. Where are main deposits of copper, iron and aluminium located, when will they become available for secondary production, in what state and shape are they?

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotor: Prof.dr. B. van de Water

What is vegetation structure and composition in SFM primary forest, secondary logged over forest (logging FSC certified and logging non certified) in comparison to primary forest? What is avian guild diversity in SFM primary forest, secondary logged over forest (logging FSC certified and logging non…

Promotie

Promotie

Promotie

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

Op 9 juli openende het nieuwe Medical Delta Fieldlab Phenomix haar deuren. In het fieldlab werken wetenschappers, zorginstellingen en bedrijven samen praktische toepassingen van metabolomics-onderzoek: onderzoek naar stofwisselingsproducten. Medical Delta sprak met de Leidse hoogleraar Thomas Hankemeier.…

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.