Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Mosselen in mosselbedden vormen een patroon dat lijkt op de organisatie van moleculen en atomen in materialen als brons, staal of rubber. Dit gedrag kan dan ook worden beschreven met hetzelfde wiskundige model.

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Promotor: Prof.dr. K.J. Batenburg

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

We consider the propagation of electrical signals through nerve fibres.

Promotor: Prof.dr. J.N. Kok

Galaxies form and live inside dark matter haloes. As a consequence, they are exposed to the tidal fields generated by the surrounding matter distribution: this imprints a preferential direction to the galaxy shapes, which leads to a coherent alignment on physically close galaxies, called intrinsic a…

Promotor: A.W. van der Vaart

Promotor: J. Schaye

Promotor: Prof.dr. M. Danhof

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Promotor: W. T. F. den Hollander, F. H. J. Redig

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Promotor: Prof.dr. S.F. Portegies Zwart

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

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Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Naar motivatie wordt al 100 jaar onderzoek verricht. En dat is niet verwonderlijk, want motivatie ligt aan de basis van ons bestaan. Waarom doen we de dingen die we doen? Waarom willen we iets, of stellen we juist uit? Maar ook in grote dingen: waarom worden we verliefd, kopen we een huis, starten we…

Promotor: Prof.dr. J.W.M. Frenken

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Op 23 juni 2019 verdedigde Zygimantas Juska zijn proefschrift 'The Role of Collective Redress Actions to Achieve Full Compensation for Violations of European Union Competition Law'. Het promotieonderzoek is begeleid door promotor prof. dr. T.R Ottervanger.

Met de huidige marktregels is het behoorlijk risicovol om in groene energie te investeren, en dat staat de strijd tegen klimaatverandering in de weg. Dat schrijft milieuwetenschapper Oscar Kraan in zijn proefschrift. Promotie op 25 april.

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Het project programmanormen bevat richtlijnen voor de inrichting van het onderwijs van de Faculteit der Geesteswetenschappen

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

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