496 zoekresultaten voor “point spread function” in de Publieke website
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Temperatuurstijging tast ecosysteem bergen aan
Hogere temperaturen leiden wereldwijd tot veranderingen in de vegetatie en de bodem van berggebieden. Een internationaal onderzoeksteam met de Leidse ecoloog Ellen Cieraad publiceerde op 25 januari in Nature over de verstoring van het ecosysteem.
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Studentencentrum PlexusKaiserstraat 25, Leiden
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WTP for qualified teachers
WTP option in abridged programme (verkort traject) for qualified teachers
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Diaspora drumming: theory and practice | English spoken
Kunst en vrije tijd, Kunst en vrije tijd
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General plant strategies and functions in wetlands: Global trait-based analyses
Promotie
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Exploring the potential of self-monitoring kidney function after transplantation
Promotie
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Divide in Urban Indian Youths’ Lives; Their Time-Use and Adaptive Functioning
Promotie
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Recovery of arm-hand function after stroke: developing neuromechanical biomarkers to optimize rehabilitation strategies
Promotie
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GDE transmembrane ecto-enzymes: novel signaling functions through GPI-anchor cleavage
Promotie
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
Promotie
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Style and Function of Female Images in Prints by Keisai Eisen (1790 – 1848)
Promotie
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Structure and function of the cerebral cortex in Huntington's disease
Promotie
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T cells in focus: formation and function of tissue-resident memory
Promotie
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Creating Capitals: The rationale, construction, and function of the imperial capitals of Assyria
Promotie
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Overcoming barriers to T cell activation, infiltration and function in tumors
Promotie
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Multiple-criteria landscapes with valleys and hills
Computer scientists from Leiden University and the University of Münster describe a new theoretical starting point for approaching difficult optimization problems. They can take into account several criteria simultaneously, instead of just one at a time.
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inflammatory bowel disease: characteristics and impact on daily functioning
Promotie
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The link between hearing loss, language, and social functioning in childhood
Promotie
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minds: Stimulating parent-child interaction to foster neurocognitive functioning in four- to eight-year-olds
Promotie
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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The stochastic geometry of non-Gaussian fields
Promotor: V. Vitelli, Co-promotor: J. Paulose
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Afdeling Environmental Biology (CML-EB)
De afdeling Environmental Biology (CML-EB) houdt zich bezig met vraagstukken rondom biodiversiteit en natuurlijke hulpbronnen op het platteland in westerse en niet-westerse gebieden.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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Magnetic Resonance Force Microscopy and the Spin Bath
There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.
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Agenda dynamics in the European Union : the interaction between the European Council and the European Commission in the policy domain of organized
The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Cavity quantum electrodynamics with quantum dots in microcavities
Promotor: Prof.dr. D. Bouwmeester
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Unconditionally secure cryptographic protocols from coding-theoretic primitives
This dissertation presents new cryptographic protocols, which can be divided into two families.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Strings and AdS/CFT at finite density
Promotores: J. Zaanen, A. Parnachev
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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Onderzoek
Het onderzoek van de sectie Cognitieve Psychologie is onder te verdelen in twee domeinen.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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On the 16-rank of class groups of quadratic number fields
Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers