Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

Promotores: H.W. Lenstra, A. Lucchini

This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.

Promotor: Prof.dr. P. Stevenhagen, Co-Promotor: J.H. Evertse

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae

If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.

Jens Iverson, universitair docent Internationaal recht en onderzoeker in het Jus Post Bellum project, heeft op 21 september 2017 zijn proefschrift verdedigd.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Assuming everywhere good reduction we generalize the class number formula of Taelman to Drinfeld modules over arbitrary coefficient rings.

How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?

Het onderzoek in dit proefschrift kijkt naar de rol van het locus ceuruleus - noradrenalinesysteem in verscheidene aspecten van menselijke cognitie, en de modulatie van de staat van het brein.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

In dit onderzoek wordt hersenontwikkeling voor het eerst direct gelinkt aan sekseverschillen en schoolprestatie. De resultaten ontkrachten de mythe dat jongens achterlopen in hersenontwikkeling.

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Het terugdringen van agressie is in de afgelopen jaren in toenemende mate een maatschappelijke prioriteit geworden. Agressie in de vroege kindertijd vergroot de kans op latere agressieproblemen en antisociaal gedrag.

Promotie

Op 7 november 2018 verdedigde Catherine Harwood haar proefschrift 'Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International Legal Order'. Het promotieonderzoek is begeleid door promotoren prof. dr. L.J. Van den…

In Nederland komt gehoorverlies voor bij 1 tot 2 op de 1000 kinderen. In ongeveer een kwart van de gevallen is de oorzaak niet bekend. De mate van gehoorverlies kent een grote variatie. In dit proefschrift worden kinderen besproken met een gehoorverlies variërend van matig (40 dB, te vergelijken met…

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Lezing, Studium Generale

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra

In this thesis three different topics in number theory are studied.

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Promotor: Prof.dr. E. Deprettere

Promotor: Prof.dr. A.W. van der Vaart

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.

Promotor: A.P. IJzerman