In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Promotie

Lezing

We consider the propagation of electrical signals through nerve fibres.

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

Data theory research on the analysis on the multidimensional data

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

This thesis is based on five papers on several topics.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Promotie

Lezing

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Promotie

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

Promotie

Lezing

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotor: Prof.dr. M. Danhof

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Promotor: A. Kros

The focus of the dissertation

Promotor: W. Jiskoot, Co-promotor: A. Hawe

Consequences for sediment stability and seston trapping

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Het Leiden Institute for Brain and Cognition (LIBC) is een Leids Universitair netwerk dat zich richt op wetenschappelijke valorisatie en outreach. Het LIBC maakt zich sterk voor het stimuleren van interdisciplinaire samenwerking op het gebied van hersenen en cognitie.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Promotie

Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).