2,042 zoekresultaten voor “microbiota-darm-brein as” in de Publieke website
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Laura SteenbergenFaculteit der Sociale Wetenschappen
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Jesse van AsFaculteit der Sociale Wetenschappen
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Suzanne Assen
Wiskunde en Natuurwetenschappen
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Graphene as biological sensor
Wangyang Fu
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Francesco Ragazzi, Students as suspects?
Beleid dat erop is gericht radicalisering tegen te gaan, ondermijnt het vertrouwen en de sociale cohesie binnen onze samenleving.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Synthesis of cyclic peptides as bioconjugation platforms
Cyclic peptides are investigated as a platform to induce different orientations between various ligands.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Career College: Working as a Data Scientist
Loopbaan en solliciteren
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Iminosugars as glucosylceramide processing enzymes inhibitors: design, synthesis and evaluation
This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Let Them Roar: Small States as Cyber Norm Entrepreneurs
Sinds de United Nations Group of Governmental Experts on the Developments in the Field of Information and Telecommunications in the Context of International Security (UN GGE) elf aanbevelingen heeft gedaan over verantwoordelijk staatsgedrag omtrent cyberspace is er een discussie gaande over internationale…
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One million spins as study tools and study objects
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The Rome Statute as Evidence of Customary International Law
Op 9 april 2019 verdedigde Yudan Tan haar proefschrift 'The Rome Statute as Evidence of Customary International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. W.A. Schabas.
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Galactic substructures as tracers of dark matter and stellar evolution
One of the most important puzzles in modern astrophysics is the nature of dark matter.
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Supramolecular peptide amphiphile nanoparticles as a novel allergy vaccine platform
Bet v1, the major allergen in birch pollen, is one of the main causes of allergies such as asthma and rhino-conjunctivitis. It is the main cause of birch pollen allergy in humans.
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Legitimation as political practice: everyday authority in Tanzania and beyond
Lezing
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Oxidants and antioxidants as targets for cardiovascular disease prevention
Promotie
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Supramolecular peptide amphiphile nanoparticles as a novel allergy vaccine
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Cyclophellitol and its derivatives: synthesis and application as beta-glycosidase inhibitors
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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The learning portfolio as a tool for stimulating reflection by student teachers
Het onderwerp van deze studie is het portfolio dat wordt gebruikt bij een lerarenopleiding als instrument om bij docenten in opleiding reflectie op hun ontwikkeling als docent te stimuleren.
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development of an assessment procedure for beginning teachers of English as a foreign language
Dit proefschrift beschrijft de ontwikkeling van een beoordelingsprocedure voor docenten, toegespitst op beginnende eerstegraads docenten Engels.
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Child Marriage as a Choice: Rethinking agency in international human rights
Op 18 maart 2020 verdedigde Hoko Horii haar proefschrift 'Child Marriage as a Choice: Rethinking agency in international human rights'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. G.A. van Klinken (UvA).
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Otjes & Louwerse, ‘Parliamentary questions as strategic party tools‘ (West European Politics)
Waarom dienen kamerleden schriftelijke vragen in? Hoe kiezen zij hun onderwerpen en de te bevragen minister? De politicologen Simon Otjes (Universiteit Groningen) en Tom Louwerse (Universiteit Leiden) onderzochten de praktijk in de Tweede Kamer en constateerden dat kamervragen deel uitmaken van de ‘voortdurende…
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Lodge & Boin, COVID-19 as the ultimate leadership challenge: making critical decisions without enough data
De coronacrisis is de ultieme test voor bestuurders. Hoe houden nationale politieke leiders zich staande in hectische, dynamische tijden? Martin Lodge (London School of Economics and Political Science) en (Arjen Boin (Instituut Politieke Wetenschap Universiteit Leiden) bekijken de ervaringen opgedaan…
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Vollaard, ‘The 2017 Dutch parliamentary elections: A fragmented picture as Rutte and Wilders draw their battle lines’
De Tweede Kamerverkiezingen die staan gepland voor maart 2017 zullen resulteren in een versnipperd parlement en een lastige kabinetsformatie, aldus de politicoloog Hans Vollaard (Universiteit Leiden) in een bijdrage aan het EUROPP-blog.
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Peer education as an opportunity for practicing respect for sexual and gender diversity
Het centrale doel van dit proefschrift is inzicht verschaffen in hoe de implementatie van een peer educator-interventie van invloed kan zijn op de houding van leerlingen tegenover LHBT-leeftijdgenoten en op de relatie tussen deze houdingen en reflectie over burgerschap.
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What's mine is yours and what yours is mine: Teacher communities as a means to increase adoption of Open Educational Resources in curricula?
Er zijn wereldwijd vele open (leer)materialen beschikbaar, maar deze worden nog niet of zeer beperkt gebruikt in het onderwijs.
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Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context
Op 12 september 2019 verdedigde Michiel Rhoen zijn proefschrift 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. Het promotieonderzoek is begeleid door promotoren prof.dr.mr.…
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Annemieke van Drenth
Faculteit der Sociale Wetenschappen
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European Union as a Global Security Actor: Common Security and Defense Policy and its Challenges in the 2011 Libya Crisis and 2014 Ukraine Conflict
Promotie
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Courts as an Arena for Societal Change
Op 8 en 9 juli 2022 was de Leidse rechtenfaculteit gastvrouw van het tweede congres van de onderzoeksgroep Conflictoplossende Instituties (COI).
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Dirk Visser over restauratie stationshond Mannes in Assen
Stationshond Mannes houdt de gemoederen in Assen flink bezig. De kunstenaar is het niet eens met het uiterlijk van zijn houten kunstwerk nadat de gemeente het heeft laten restaureren en zegt imagoschade te lijden. Assen moet de hond in ere herstellen, anders stapt de kunstenaar naar de rechter.
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Petra BarneveldFaculteit der Sociale Wetenschappen