48 zoekresultaten voor “metabolite identification” in de Publieke website
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Ruben HueleWiskunde en Natuurwetenschappen
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The evolution of chemical diversity in plants : pyrrolizidine alkaloids and cytochrome P450s in Jacobaea
Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
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Early identification and resolution of rheumatoid arthritis
Promotie
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Promotie
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Image guided surgery: clinical validation of lesion identification technologies and exploration of nerve sparing approaches
Promotie
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Evaluation of the environmental impact of products (EIPRO)
Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Mining Sensor Data from Complex Systems
Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Knots in plasma
A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.
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Identification of neural and non-neural contributors to joint stiffness in upper motor neuron disease
Promotie
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Identification and characterisation of anti-citrullinated protein antibody (ACPA)-producing B cells in patients with rheumatoid arthritis (RA)
Promotie
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Empirical signatures of universality, hierarchy and clustering in culture
In this thesis,
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The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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intra-cardiac vortex flow from 4D Flow MRI: Quantification, automatic identification and association with energy loss
Promotie
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De Leidse Papyrologie+ groep
De Leidse Universiteit heeft een lange en waardevolle traditie in de Papyrologie.
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Development of life cycle assessment for residue-based bioenergy
Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?
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Marieke Slootman wint NSV Dissertatieprijs 2015
Antropoloog Marieke Slootman heeft voor haar proefschrift over de etnische identificatie onder Marokkaanse en Turkse Nederlanders de Dissertatieprijs 2015 van de Nederlandse Sociologische Vereniging (NSV) ontvangen.
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PhD candidate in natural and synthetic microbial biochemistry
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
- Teacher in the field of the social sciences and a communication officer
- Education coordinator
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Sensoren meten speelgedrag van kleuters op het schoolplein
Vrije speeltijd en fysiek spel zijn van groot belang voor de sociale ontwikkeling van jonge kinderen. Dat blijkt uit innovatief onderzoek van ontwikkelingspsychologen en informatici van de Universiteit Leiden.
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Recordaantal Leidse studenten krijgt Jong Talent Prijzen
Maar liefst twaalf studenten van de Universiteit Leiden hebben een Jong Talent Prijs ontvangen van de Koninklijke Hollandsche Maatschappij der Wetenschappen in Haarlem, een record. Tijdens de feestelijke ceremonie op 25 november kregen vijf masterstudenten een Jong Talent Afstudeerprijs voor hun scriptie…
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CCLS Webinar: Computational Omics Strategies for Natural Product Discovery
Lezing
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Zeven nieuwe Medical Delta-hoogleraren
Medical Delta benoemt zeven hoogleraren die een brug gaan slaan tussen de medische werelden van Leiden, Delft en Rotterdam.
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This Week’s Discoveries | 17 April 2018
Lezing
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Understanding disease suppressive soils
Promotie
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Top Lectures: Dolf Weijers
Lezing
- Clinical implications of immune cell infiltration in vulvar intraepithelial neoplasia
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Best Spaans proefschrift in Soil Science in 2015 voor CML onderzoeker Daniel Arenas Lago
De
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Joan van der Waals colloquium
Lezing
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Development of healthy food additives using data science
Lezing, This Week's Discoveries
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Afscheidssymposium Prof. dr. M. Danhof: "Four decades of Research in Pharmacokinetics, Pharmacodynamics and beyond...",
Congres/symposium
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Data Science meets Humanities
Lezing, Seminar
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Wel of geen PhD doen? Speeddate erover met alumni!
Loopbaan en solliciteren
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Wetenschaps- en onderwijsbeleid
De YAL laat zich horen over beleidskwesties.