146 zoekresultaten voor “mass spectrometry” in de Publieke website
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Mass spectrometry based protein profiling
Promotie
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Mass spectrometry based protein profiling
Promotie
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Clinical Glycomics of Antibodies by Mass Spectrometry
Promotie
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Data analysis for mass spectrometry imaging: methods and applications
Promotie
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Biomarker Discovery in High Grade Sarcomas by Mass Spectrometry Imaging
Promotie
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Lab-on-a-tissue: Optimization of On-Tissue Chemistry for Improved Mass Spectrometry Imaging
Promotie
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Statistical Methods for Mass Spectrometry-based Clinical Proteomics
Promotie
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Monitoring and detection of nanomaterials in biological media.
How do nanoparticles bioaccumulate and biodistribute in organisms?
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra
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Paolo de MasAfrika-Studiecentrum
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Unveiling protostellar disk formation around low-mass stars
Promotor: Prof.dr. E.F. van Dishoeck
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Vier Rubicons naar Leiden
De tweede toekenningsronde van de Rubiconsubsidies heeft vier gehonoreerde onderzoeksprojecten opgeleverd voor de Universiteit Leiden. Drie jonge Leidse wetenschappers mogen onderzoek doen aan prestigieuze onderzoeksinstellingen in het buitenland en één onderzoeker komt naar Leiden toe.
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The puzzle of protoplanetary disk masses
My work focuses on a class of astronomical objects called protoplanetary disks.
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5th LCDS meeting: Electron Microscopy and Data Science
Congres/symposium
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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The connection between mass and light in galaxy clusters
Promotor: Koen Kuijken Co-promotor: Henk Hoekstra
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Some Assembly Required: The Structural Evolution and Mass Assembly of Galaxies at z
This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.
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simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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The Great Collapse
Promotor: Prof.dr. S.F. Portegies Zwart
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The astrochemical factory: A solid base for interstellar reactions
In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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The Masses and the Muses, transformatie van Teylers Museum
Aan het einde van de achttiende en het begin van de negentiende eeuw was Teylers Museum het belangrijkste onderzoeksinstituut van ons land voor kunsten en wetenschappen. In de twintigste eeuw werd zelfs ‘s werelds meest toonaangevende fysicus, de Leidse hoogleraar Hendrik Antoon Lorentz aangetrokken.…
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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low- and high-mass protostars. Surveying hot molecular gas with Herschel
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg
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High-throughput mass spectrometric N-glycomics
Promotie
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The puzzle of protoplanetary disk masses
Promotie
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Novel mass spectrometric applications in clinical microbiology
Promotie
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StepTalk: Mass Starvation: The History and Future of Famine
Debat, StepTalks
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The Connection Between Mass and Light in Galaxy Clusters
Promotie
- Lezing 'Pervasive Punishment: Making sense of 'mass supervision’
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Some Assembly Required: The Structural Evolution and Mass Assembly of Galaxies at z
Promotie
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structural study of light-harvesting complexes : an investigation with MAS-NMR
Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.
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FGGA Research Seminar: Mass Media as a Source of Public Responsiveness
Lezing, Seminar
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Modeling interstellar bubbles: near and far
Promotor: Prof. dr. A.G.G.M. Tielens
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simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
Promotie
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Mucosal Immunology revisited through Mass Cytometry: From Biology to Bioinformatics and Back
Promotie
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The interplay between stars, gas and dust in faint star-forming galaxies
When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.
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Unveiling dark structures with accurate weak lensing
Improvements of weak gravitational lensing shape measurements are presented and some used for data analysis.
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst