Promotor: J. Zaanen

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

LCD-schermen gebruiken vloeibare kristallen die weliswaar een vloeistof vormen maar toch in hoge mate geordend zijn. Een nieuwe theorie brengt nu het samenspel in kaart tussen orde, temperatuur en symmetrie. Publicatie in Physical Review X.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Promotor: J. Zaanen, Co-Promotor: V. Juricic

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

De European Research Council heeft aan vier Leidse onderzoekers een ERC Consolidator Grant toegekend. Met deze beurs van maximaal twee miljoen euro kunnen zij hun wetenschappelijk onderzoek voortzetten en uitbreiden.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

Theoretisch natuurkundige Luca Giomi ontvangt een ERC Consolidator grant van 2 miljoen euro, waarmee hij vloeiende cellen gaat onderzoeken.

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Materialen zijn gasvorming, vloeibaar of vast, afhankelijk van de manier waarop hun moleculen reageren op temperatuur en druk. Maar wat als de bouwstenen zelf-draaiende deeltjes zijn in plaats van gewone moleculen? Theoretisch natuurkundigen hebben ontdekt wat de fase bepaalt van die kunstmatige materialen.…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Promotor: T.J. Aartsma, Co-promotor: R.N. Frese

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Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Promotor: Prof.dr. M.L. van Hecke

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

Promotor: M.A.G.J. Orrit

Promotor: G.P. van Wezel

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Promotor: A.P. IJzerman