Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

Promotor: J. Zaanen

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Promotie

Promotie

Promotor: M.A.G.J. Orrit

Promotor: Prof.dr. M.L. van Hecke

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Promotie

Promotie

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

Lezing

Promotie

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Promotor: Prof.dr. G.P. van Wezel

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).

Met de NMR faciliteit doen we onderzoek naar de synthese van paramagnetische moleculen om kennis te vergaren over de structuur en dynamiek van eiwitten. Deze kennis kan dienen als basis voor een medicijn dat zich hecht aan een eiwit of voor de ontwikkeling van vaccins. Medicijnontwikkeling is één van…

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

Promotor: G.P. van Wezel

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Hoogleraar Rechtssociologie Maartje van der Woude gaat op zoek naar innovatieve manieren om onderwerpen die doorgaans als ‘moeilijk bespreekbaar’ worden ervaren – zoals bijvoorbeeld racisme, etnisch profileren, uitsluiting, crimmigratie – bespreekbaar te maken met een breed publiek.

Het LION heeft er een nieuwe universitair docent bij: Alexandre Morin. Hij doet onderzoek naar Alexandre Morin is a new associate professor at LION, who will be researching actieve materie. In de onderstaande video (in het Engels) vertelt hij over zijn werk.

Het kabinet komt met een steunpakket om bedrijven en zelfstandigen door de coronacrisis heen te slepen. Het is volgens econoom Wimar Bolhuis een sterk signaal dat de overheid bereid is om de economische klap op te vangen. ‘Voorlopig is er voldoende budgettaire vuurkracht.’

LCD-schermen gebruiken vloeibare kristallen die weliswaar een vloeistof vormen maar toch in hoge mate geordend zijn. Een nieuwe theorie brengt nu het samenspel in kaart tussen orde, temperatuur en symmetrie. Publicatie in Physical Review X.

Op donderdag 15 februari 2018 ontving het Hazelhoff Centre for Financial Law Roel Janssen, financieel-economisch journalist en schrijver, voor de vijftiende Hazelhoff Guest Lecture.