240 zoekresultaten voor “lipid organization” in de Publieke website
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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A Model Membrane Approach to Elucidate the Molecular Organization in the Skin Barrier
Promotor: J. A. Bouwstra
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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Superstructures of lipids and graphene
This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Sylvestre BonnetWiskunde en Natuurwetenschappen
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions
Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn
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Anjali PanditWiskunde en Natuurwetenschappen
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Michiel VeldhuisWiskunde en Natuurwetenschappen
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Met grafeen door het lichaam reizen
Het is onderzoekers voor het eerst gelukt grafeen op een stabiele laag vetten, ofwel lipiden, te plaatsen. Omringd door een beschermende laag van lipiden zou grafeen in het lichaam als een veelzijdige sensor kunnen dienen. De resultaten zijn de eerste stap naar zo’n omhulsel en zijn op 28 september…
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Een vette oplossing voor eczeem
Farmacoloog Walter Boiten ontwikkelde een nieuwe methode om de hoeveelheid vetten in iemands huid te kunnen bepalen. Met de methode testte hij de effecten van een nieuwe crème die hij ontwikkelde voor eczeempatiënten. De eerste resultaten zijn veelbelovend. Boiten promoveert op 15 januari.
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Lipid mediated colloidal interactions
Promotie
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International Labour Organization: tumult op de wereldwijde arbeidsmarkt
Al sinds 1919 strijdt de International Labour Organization (ILO) voor de rechten van werkenden wereldwijd. De Universiteit Leiden is op 7 februari gastvrouw van het symposium waarmee de ILO haar 100-jarig bestaan viert. De Leidse emeritus hoogleraar Internationaal Arbeidsrecht Paul van der Heijden was…
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Superstructures of lipids and graphene
Promotie
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Lipids as therapeutic targets for barrier repair in skin diseases
Promotie
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Managing Diversity in Organizations
Lezing, Studium Generale
- Managing Diversity in Organizations
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Genetic and methodological aspects of statin-induced lipid response
Promotie
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The interplay between lipids and the immune system in atherosclerosis
Promotie
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Greased lighting: implications of circadian lipid metabolism for cardiometabolic health
Promotie
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Leadership and inclusiveness in public organizations
Promotie
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Klimaatverandering stelt Afrikaanse grazers voor moeilijke keuze
Leeuwen beperken hun prooidieren, zoals zebra’s en gnoes, in hun mogelijkheden zich aan te passen aan een opwarmende aarde. Dat ontdekte Leidse onderzoeker Michiel Veldhuis van het Centrum voor Milieuwetenschappen in Leiden samen met internationale collega’s. Het onderzoek is op 1 juni in Nature Ecology…
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On the geometry of demixing: a study of lipid phase separation on curved surfaces
Promotie
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pluripotent stem cells: adipocyte size, insulin signaling and hepatic lipids
Promotie
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Aleydis Nissen wint European Public Law Organization-prijs voor beste thesis
De postdoc krijgt de onderscheiding voor haar proefschrift over de rol van Europese Unie-lidstaten bij het voorkomen van mensenrechtenschendingen door bedrijven.
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Lunch Research Seminar: Youth Party Organizations in Argentina
Lezing
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Promotie
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Call for Papers: Behavioural Approaches in International Law
A series of workshops at Leiden University and the University of Hamburg will act as a forum in which international legal scholars whose research adopts a behavioural approach can present their works-in-progress and gain feedback from a broad range of peers, including scholars in economics and cognitive…
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Networking and performance in public organizations: A study of primary schools in the Netherlands
Promotie
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The Wisdom of Virgil: The Aeneid, Its Commentaries, and the Organization of Knowledge in Early Modern Scholarship
Promotie
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Growth-induced self-organization in bacterial colonies
Promotie
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Physics implications of shape on biological function
Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame
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Emerging approaches to study cell-cell interactions
The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds.
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Photocatalytic redox reactions at the surface of liposomes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Natural Products Lab
Wij richten ons op natuurlijke producten van onderzoek, de traditionele geneeskunde, etnobotanie en fytochemie.
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Governance of Innovation Project Management: Necessary and Neglected
Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries