51 zoekresultaten voor “invasive lobular carcinoma ilc ” in de Publieke website
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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evolution in an invasive plant species: evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive Jacobaea
Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling
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Managing invasive Aspergillosis: impact on health and personalized prevention or treatment strategies
Promotie
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PI3K signaling and adherens junctions in invasive lobular breast cancer
Promotie
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Emily StrangeWiskunde en Natuurwetenschappen
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
Promotie
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Wil TamisWiskunde en Natuurwetenschappen
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Vulvar squamous cell carcinoma
Promotie
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Pharmacogenetics of sunitinib in metastatic renal cell carcinoma
Promotie
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Understanding archaeological landscapes through non-invasive approaches
Lezing, Faculty Lecture
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Clinical evidence in minimally invasive gynaecology: sense and non sense
Promotie
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Minimally invasive diagnostics and immunotherapy of lung cancer
Promotie
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Advancements in minimally invasive image-guided liver therapies
Promotie
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Implementing New Surgical Instruments in Minimally Invasive Surgery
Promotie
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Welcome to the stone age. Minimally invasive treatments for urolithiasis
Promotie
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Ductal carcinoma in situ of the breast: cancer precursor or not?
Promotie
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Basic and clinical features of cutaneous squamous cell carcinoma in organ transplant recipients
Promotie
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Optimization of suntinib treatment in metastatic renal cell carcinoma: pharmacogenetic evidence and challenges
Promotie
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From molecules to monitoring: Integrating genetic tools into freshwater quality assessments
Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.
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Recent innovations in minimally invasive anterior and posterior lamellar keratoplasty
Promotie
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Evidence based evaluation of new techniques in minimally invasive surgery
Promotie
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Differentiated Thyroid Carcinoma. Studies on diagnosis, treatment- related side effects and well-being
Promotie
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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Automated planning approaches for non-invasive cardiac valve replacement procedures from CT angiography
Promotie
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Tachycardia in Repaired Tetralogy of Fallot: Risk Stratification and Invasive Treatment
Promotie
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Piepkleine, pijnvrije vaccinaties: micronaalden en nanodeeltjes
Als het aan promovendus Guangsheng Du ligt, hoeven patiënten niet meer bang te zijn voor dokters met grote naalden. De onderzoeker van het Leiden Academic Centre for Drug Research onderzocht het gebruik van micronaaldjes en nanodeeltjes als nieuw systeem voor vaccinatie. ‘Ik wil een methode ontwikkelen…
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Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
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Beyond random and forbidden interactions : how optimizing energy gain results in morphological matching among subalpine Asteraceae and their
Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Connecting dots between natural and artificial Photosynthesis
Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Competition on bird feeeders between introduced Ring-necked parakeets and native bird species in the Netherlands
Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?
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Media en interactie
Media & interactie is waar kunstmatige intelligentie en machine learning samenkomen met filosofie, cognitieve wetenschap en de creatieve kunsten. Voorbeelden van onderzoeksvragen in dit domein zijn: ‘Kan een algoritme naar menselijke maatstaven creatief zijn?', 'Kunnen creatieve processen, zoals het…
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Comparative ecology and genetics of sympatric wild cats in relation to human wildlife conflict in Bardia National Park, Nepal
What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…
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Veel aandacht voor uitzetten Japanse bladvlo in Nederland
Op 22 oktober mocht voor het eerst in de Nederlandse geschiedenis een uitheemse diersoort worden uitgezet in de natuur om een invasieve plantensoort te bestrijden. Suzanne Lommen, entomoloog bij het Instituut Biologie Leiden, coördineert de Nederlandse veldproeven. Nationale en internationale media…
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Arts-onderzoeker Janneke Stalenhoef ontvangt International Investigator Award
Arts-onderzoeker Infectieziekten Janneke Stalenhoef heeft tijdens de IDWeek 2015 in San Diego een International Investigator Award ontvangen voor haar onderzoek. De IDWeek is de jaarlijkse bijeenkomst van the Infectious Diseases Society of America (IDSA).
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Artikelprijs voor psycholoog Andreas Burger
Tijdens de jaarlijkse bijeenkomst van de onderzoeksschool voor Experimentele Psychopathologie heeft Andreas Burger (Klinische psychologie) de prijs gewonnen voor het beste artikel van 2017.
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Bezoek de Leidse voorronde van FameLab
Welke twee Leidse bètawetenschappers presenteren hun onderzoek het aanstekelijkst in drie minuten? Misschien wel degenen met de meeste supporters. Op 14 februari vindt de Leidse voorronde van FameLab plaats. Meld je nu aan als publiek!
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LCN2 Seminar: Critical Brain Dynamics
Lezing
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Leids Universitair Medisch Centrum
In het Leids Universitair Medisch Centrum (LUMC) streven we naar de verbetering van de gezondheidszorg en de gezondheid van mensen.
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This Week’s Discoveries | 22 March 2016
Lezing
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NGL lezing: Single molecules and single gold nanoparticles in the spotlight
Lezing